Results 91 to 100 of about 151,766 (312)

Characterization of milk fatty acids based on genetic and herd parameters

open access: yes, 2012
The objective of this study was to characterize the fatty acids (FA) in milk based on genetic and herd parameters to investigate the origin of the different FA in milk.
Bovenhuis, H.   +4 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Estimation of the Genetic Parameters for Test-Day Milk, in Teleorman Black Head Sheep

open access: yesScientific Papers Animal Science and Biotechnologies, 2023
The objective of this study was to determine the genetic parameters represented by heritability for test-day milk yield and the genetic correlation between test-days milk yield and the breeding value for Teleorman Black Head sheep. The genetic parameters
Rodica Stefania Pelmus   +6 more
doaj  

The differentiated milk recording when milking into the milk line

open access: yesАграрная наука Евро-Северо-Востока, 2019
The article is devoted to theoretical and experimental substantiation of technical capability of the differentiated recording of milk when milking into the milk line.
A. A. Rylov   +2 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Characteristics of milk production traits of Balkan goats raised under “low-input” production systems

open access: yesMljekarstvo, 2010
In order to analyse dairy production traits (milk yield in full lactation, milk fat content, daily milk yield and length of lactation) of Balkan goats raised under “low-input” production systems, data on 440 lactation records from 118 does raised on 9 ...
Vladan Bogdanović
doaj  

Detection on OAR7 of QTL affecting fat and protein yields in dairy sheep

open access: yesItalian Journal of Animal Science, 2010
The objective of this paper was identifying QTL that affect fat and protein yields in dairy sheep independently of milk yield. Data were collected in an experimental flock of 887 ewes organized in a daughter design. QTL detection focused on OAR7 where 13
Antonello Carta   +5 more
doaj   +1 more source

Investigations on Milk Flow and Milk Yield from Teats with Milk Flow Disorders

open access: yesJournal of Dairy Science, 2002
The objective of this study was to investigate peak milk flow, average milk flow, and milk yield in teats with milk flow disorders. A total of 100 hard milking teats were studied in 97 cows. Teats with milk flow disorders were examined endoscopically.
Julia, Ouerengässer   +4 more
openaire   +2 more sources

Genetic relationships between calving interval and body condition score conditional on milk yield

open access: yes, 2002
Body condition score (BCS) is a useful tool in assessing the energy status of dairy cattle. Previous research has shown that it is heritable and genetically correlated to reproductive performance.
Coffey, M.P.   +3 more
core  

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