Results 211 to 220 of about 1,965,698 (303)

Material‐Encoded Synchronization of Immunogenic Cell Death With Adenosine A2A Receptor Blockade Reprograms the Tumor Microenvironment

open access: yesAdvanced Science, EarlyView.
A bismuth–copper diselenide–based nanoplatform (BSCS@PHY) coordinates immunogenic cell death with local A2A receptor blockade in 4T1 tumors. Thermally triggered shell melting exposes catalytic surfaces for glutathione depletion and chemodynamic ROS generation, while co‐delivering an A2AR antagonist and yeast‐wall adjuvant to enhance dendritic‐cell ...
Xiangting Yi   +12 more
wiley   +1 more source

Association study of the <i>CSN2</i> gene with milk yield in the Sapera goat. [PDF]

open access: yesJ Adv Vet Anim Res
Asmarasari SA   +14 more
europepmc   +1 more source

Matrix Stiffness Induces Endothelial Network Senescence

open access: yesAdvanced Science, EarlyView.
Using a 3D human in vitro model that decouples mechanical stress from inflammatory or biochemical signals, matrix stiffening induces a senescence phenotype in endothelial networks. This mechano‐induced senescence activates Notch signaling, and pharmacologic Notch inhibition attenuates this stiffness‐induced senescence.
Jiyeon Song   +6 more
wiley   +1 more source

Differential responses to soybean meal and canola meal based diet protein levels in mid-lactation dairy cows with different milk yield and parity. [PDF]

open access: yesVet Anim Sci
Yang ZQ   +12 more
europepmc   +1 more source

ZER1 Restrains Pressure Overload‐Induced Cardiac Remodeling by Targeting DVL2 for Gly/N‐Degron‐Dependent Degradation

open access: yesAdvanced Science, EarlyView.
Pressure overload suppresses cardiomyocyte ZER1, weakening CRL2Zer1‐mediated DVL2 degradation and allowing DVL2 accumulation. Elevated DVL2 activates CaMKII‐HDAC4‐MEF2C signaling, drives fetal gene reactivation, and promotes pathological remodeling.
Mingchao Jiang   +27 more
wiley   +1 more source

Effect of Milking Throughout Pregnancy on Milk Yield in the Succeeding Lactation

open access: yesJournal of Dairy Science, 1966
A, Smith, J V, Wheelock, F H, Dodd
openaire   +2 more sources

Integrative Omics Analysis Reveals the Regulation of Hypoxia Tolerance in Large Yellow Croaker (Larimichthys crocea) via the Lipoic Acid Synthase (lias) Gene

open access: yesAdvanced Science, EarlyView.
Lipoic acid synthase (lias) can regulate α‐KG levels through lipoylation, thereby negatively regulating HIF‐1α protein levels via PHD under hypoixa. The Hap2 allele of lias exhibits lower expression levels than Hap1, leading to the accumulation of more HIF‐1α protein and thereby enhancing hypoxia tolerance. ABSTRACT Hypoxia stress seriously affects the
Jie Ding   +7 more
wiley   +1 more source

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