Results 131 to 140 of about 5,065,958 (389)

A Gaia-Enceladus Analog in the EAGLE Simulation: Insights into the Early Evolution of the Milky Way [PDF]

, 2019
We identify a simulated Milky Way analog in the EAGLE suite of cosmological hydrodynamical simulations. This galaxy not only shares similar global properties as the Milky Way, but was specifically selected because its merger history resembles that currently known for the Milky Way.
arxiv   +1 more source

The Circular Velocity Curve of the Milky Way from 5 to 25 kpc [PDF]

Astrophysical Journal, 2018
We measure the circular velocity curve vc(R) of the Milky Way with the highest precision to date across Galactocentric distances of 5 ≤ R ≤ 25 kpc. Our analysis draws on the six-dimensional phase-space coordinates of ≳23,000 luminous red giant stars, for
A. Eilers, D. Hogg, H. Rix, M. Ness
semanticscholar   +1 more source

Dysfunctional tetraspanin 7 (TSP‐7) in Caenorhabditis elegans promotes; increases in average life‐ & health‐span, stress‐induced survival and motility

FEBS Open Bio, EarlyView.
The C. elegans tetraspanin‐7 (tsp‐7) is a homologue of human CD63, which is a negative regulator of autophagy. The C. elegans strain, tm5761, has a dysfunctional (knockout) tsp‐7 gene. When compared to the wild‐type strain, the tm5761 strain shows increased: life‐ and health‐span; thermotolerance, and stress‐induced locomotion.
Brogan Jones, Laurence Seabra, Francesco Michelangeli   +2 more
wiley   +1 more source

An Inward-moving and Asymmetric Velocity Wave Detected in LAMOST-Gaia

The Astrophysical Journal Letters
The phase space, as coded by kinematic parameters and chemical abundances, is crucial for understanding the formation of the Galactic disk. Using red giant stars from the Galactic thin disk with [Fe/H] > − 0.8 and low- α ratios identified in LAMOST-Gaia,
Yuqin Chen, Gang Zhao, Wenbo Wu, Zixi Guo, Haopeng Zhang, Zhuohan Li   +5 more
doaj   +1 more source

Breaking up the Magellanic Group into the Milky Way Halo: Understanding the Local Dwarf Galaxy Properties [PDF]

arXiv, 2008
We use a numerical simulation of a loose group containing a Milky Way halo to probe that in the hierarchical universe the Magellanic Clouds and some dSphs have been accreted into the Milky Way halo from a late infalling group of dwarfs. Our simulations show that the tidal breakup of the Magellanic group occurs before it enters the Milky Way halo.
arxiv  

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

FEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli, Andrea Spinaci, Cui Chang, Rosaria Volpini, Catia Lambertucci, Matteo Landriscina, Vincenza Conteduca, Consuelo Amantini, Cristina Aguzzi, Laura Zeppa, Martina Giangrossi, Laura Soverchia, Matteo Santoni, Massimo Nabissi, Giorgio Santoni, Carlo Polidori   +15 more
wiley   +1 more source

Locally Cold Flows from Large-Scale Structure

, 2011
We show that the "cold" Hubble flow observed for galaxies around the Milky Way does not represent a problem in cosmology but is due to the particular geometry and dynamics of our local wall.
A. S. Szalay, Aragon-Calvo, Aragón-Calvo, Aragón-Calvo, Baryshev, Cabral, Chernin, Ekholm, Governato, Hartwick, Hawkins, Hoffman, Hoyle, Icke, Icke, J. Silk, Karachentsev, Karachentsev, Karachentsev, Klypin, Landy, M. A. Aragon-Calvo, Macciò, Martinez-Vaquero, Navarro, Peebles, Peebles, Peirani, Peirani, Sandage, Sandage, Schaap, Scoccimarro, Springel, Teerikorpi, Tully, Tully, van de Weygaert, White, Zehavi, Zel’dovich   +40 more
core   +1 more source

Icarus Revisited: An Ancient, Metal-poor Accreted Stellar Stream in the Disk of the Milky Way

The Astrophysical Journal
The search for accreted satellites in the Galactic disk is a challenging task, to which Gaia plays a crucial role in synergy with ground-based spectroscopic surveys. In 2021, P. Re Fiorentin et al.
Paola Re Fiorentin, Alessandro Spagna, Mario G. Lattanzi, Michele Cignoni, Sara Vitali   +4 more
doaj   +1 more source

From the Outside Looking in: What can Milky Way Analogues Tell us About the Star Formation Rate of Our Own Galaxy? [PDF]

, 2019
The Milky Way has been described as an anaemic spiral, but is its star formation rate (SFR) unusually low when compared to its peers? To answer this question, we define a sample of Milky Way Analogues (MWAs) based on stringent cuts on the best literature estimates of non-transient structural features for the Milky Way.
arxiv   +1 more source

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

FEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu, Yuhao Zhang, Tiantian Ge, Hao Wu, Yongbin Ma, Honghua Ye, Fei Guo   +6 more
wiley   +1 more source