Results 141 to 150 of about 4,796,996 (337)

Dual‐Nanoparticle Engineered Hydrogel Reverses Bicellular Oxidative Stress to Accelerate Diabetic Fracture Healing

open access: yesAdvanced Functional Materials, EarlyView.
CD105‐LNPs and PS‐LNPs can deliver α‐lipoic acid to bone marrow mesenchymal stem cells and bone marrow‐derived macrophages, reversing high glucose‐induced oxidative stress while enhancing osteogenesis and M2 polarization. Integrating both nanoparticles into glucose‐responsive hyaluronic acid hydrogel forms DLNPs@HA hydrogel, which accelerates diabetic ...
Yanzhi Zhao   +11 more
wiley   +1 more source

Main-sequence Turnoff Stars as Probes of the Ancient Galactic Relic: Chemo-dynamical Analysis of a Pilot Sample

open access: yesThe Astrophysical Journal
The main-sequence turnoff (MSTO) stars well preserve the chemical properties where they were born, making them ideal tracers for studying the stellar population. We perform a detailed chemo-dynamical analysis on moderately metal-poor (−2.0 
Renjing Xie   +7 more
doaj   +1 more source

A scaling relation for the molecular cloud lifetime in Milky Way-like galaxies. [PDF]

open access: yesMon Not R Astron Soc, 2021
Jeffreson SMR   +6 more
europepmc   +1 more source

Reconfigurable Nucleic Acid Nanoparticles with Therapeutic RNAi Responses to Intracellular Disease Markers

open access: yesAdvanced Functional Materials, EarlyView.
Many known diseases arise from dysregulated gene expression, and differentially expressed genes can serve as biomarkers to distinguish diseased cells from healthy tissues. In this study, reconfigurable nucleic acid nanoparticles (recNANPs) are introduced that can detect overexpressed cancer biomarkers and subsequently release RNAi inducers to silence ...
Yelixza I. Avila   +7 more
wiley   +1 more source

The Structure, Populations, and Kinematics of the Milky Way Central and Inner Bulge with OGLE, APOGEE, and Gaia Data

open access: yesThe Astrophysical Journal
We present an analysis of the structure, kinematics, and chemo-dynamical properties of the Milky Way bulge using RR Lyrae stars from Optical Gravitational Lensing Experiment (OGLE), and giant stars from APOGEE and Gaia that have distances placing them in
Xiao Han   +7 more
doaj   +1 more source

Antibody‐Programmable Bimetallic Nanozymes for Transcriptional Blockade Therapy in HER2/ER‐Positive Breast Cancer

open access: yesAdvanced Functional Materials, EarlyView.
Zr‐Fe MOF@Ribociclib@Herceptin (ZFRH) efficiently targets/kills Human Epidermal Growth Factor Receptor 2/Estrogen Receptor‐positive (HER2/ER+) breast cancer cells. It combats tumors by: 1) Elevating ROS, altering redox balance; 2) Inhibiting transcription; 3) Inducing pyroptosis.
Hongkun Miao   +8 more
wiley   +1 more source

Synthetic Gaia DR3 Surveys from the FIRE Cosmological Simulations of Milky Way-mass Galaxies

open access: yesThe Astrophysical Journal
The third data release (DR3) of Gaia has provided a fivefold increase in the number of radial velocity measurements of stars, as well as a stark improvement in parallax and proper motion measurements.
Tri Nguyen   +6 more
doaj   +1 more source

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