Results 151 to 160 of about 151,078 (334)

Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization

open access: yesAdvanced Healthcare Materials, EarlyView.
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng 
Molood Behbahanipour   +11 more
wiley   +1 more source

State‐of‐the‐Art, Insights, and Perspectives for MOFs‐Nanocomposites and MOF‐Derived (Nano)Materials

open access: yesAdvanced Materials, EarlyView.
Different approaches to MOF‐NP composite formation, such as ship‐in‐a‐bottle, bottle‐around‐the‐ship and in situ one‐step synthesis, are used. Owing to synergistic effects, the advantageous features of the components of the composites are beneficially combined, and their individual drawbacks are mitigated.
Stefanos Mourdikoudis   +6 more
wiley   +1 more source

Main-sequence Turnoff Stars as Probes of the Ancient Galactic Relic: Chemo-dynamical Analysis of a Pilot Sample

open access: yesThe Astrophysical Journal
The main-sequence turnoff (MSTO) stars well preserve the chemical properties where they were born, making them ideal tracers for studying the stellar population. We perform a detailed chemo-dynamical analysis on moderately metal-poor (−2.0 
Renjing Xie   +7 more
doaj   +1 more source

Bi‐Functional Topospecific Nanoparticles to Promote Immune‐Tumor Cell Engagement as A New Immunotherapeutic Strategy

open access: yesAdvanced Materials, EarlyView.
A Janus‐engineered nanoplatform (J‐pHLIP‐PD1), featuring separate tumor‐ and immune‐targeting faces, bridges melanoma cells and cytotoxic T lymphocytes using toposelective pHLIP and anti‐PD‐1 presentation. This strategy elicits robust antitumor responses, promotes immunogenic tumor cell death, suppresses lung metastasis in vivo, and provides a modular,
Alba Ortuño‐Bernal   +9 more
wiley   +1 more source

The Structure, Populations, and Kinematics of the Milky Way Central and Inner Bulge with OGLE, APOGEE, and Gaia Data

open access: yesThe Astrophysical Journal
We present an analysis of the structure, kinematics, and chemo-dynamical properties of the Milky Way bulge using RR Lyrae stars from Optical Gravitational Lensing Experiment (OGLE), and giant stars from APOGEE and Gaia that have distances placing them in
Xiao Han   +7 more
doaj   +1 more source

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