Results 171 to 180 of about 23,339 (302)

Computer Vision Techniques Demonstrate Robust Orientation Measurement of the Milky Way Despite Image Motion. [PDF]

Biomimetics (Basel)
Tao Y, Perera A, Teague S, McIntyre T, Warrant E, Chahl J.   +5 more
europepmc   +1 more source

The local spiral structure of the Milky Way. [PDF]

Sci Adv, 2016
Xu Y, Reid M, Dame T, Menten K, Sakai N, Li J, Brunthaler A, Moscadelli L, Zhang B, Zheng X.   +9 more
europepmc   +1 more source

TRIM47 Regulates Energy Metabolism via Glycolytic Reprogramming to Drive Hepatocellular Carcinoma Progression and Represents an Efficient Therapeutic Target

Advanced Science, EarlyView.
This study identifies TRIM47 as a key driver of liver cancer progression by promoting glycolysis through ubiquitin‐mediated degradation of the gluconeogenic enzyme FBP1. TRIM47 enhances glucose uptake, lactate and ATP production, and tumor growth and metastasis.
Weijie Sun, Yihang Yuan, Qian Qiu, Kexuan Tan, Xutong Li, Haotian Li, Luyang Kang, Yuting Gu, Ziheng Zhang, Jiayu He, Jiali Li, Junjie Lin, Zihan Xie, Kexing Han, Jiabin Li, Yang Zhang, Ting Wu, Yufeng Gao   +17 more
wiley   +1 more source

Hypertriglyceridemia-Induced Acute Pancreatitis-The Milky Way Constellation-The Seven-Year Experience of a Large Tertiary Centre. [PDF]

Diagnostics (Basel)
Edu AV, Pahomeanu MR, Ghiță AI, Constantinescu DI, Grigore DG, Bota AD, Luta-Dumitrașcu DM, Țieranu CG, Negreanu L.   +8 more
europepmc   +1 more source

Deciphering Residual Emissions: Time-dependent Models for the Nonthermal Interstellar Radiation from the Milky Way. [PDF]

Astrophys J, 2019
Porter TA, Jóhannesson G, Moskalenko IV.   +2 more
europepmc   +1 more source

The Bulge of the Milky Way and cosmic rays [PDF]

, 1993
F. Jansen, K.‐P. Wenzel, D. O. Sullivan, A. Thompson   +3 more
openalex   +1 more source

RIG‐I Mediated Neuron‐Specific IFN Type 1 Signaling in FUS‐ALS Induces Neurodegeneration and Offers New Biomarker‐Driven Individualized Treatment Options for (FUS‐)ALS

Advanced Science, EarlyView.
Using iPSC‐derived motoneurons and postmortem tissue from FUS‐ALS patients, it is demonstrated that increased mitochondrial transcription leads to elevated cytosolic double‐stranded RNA (dsRNA) levels. This aberrant accumulation activates a RIG‐I–dependent innate immune response leading to neurodegeneration, which is amenable for FDA‐ and EMA‐approved ...
Marcel Naumann, Theresa M. Wierschin, Stefanie Kretschmer, Banaja P. Dash, Aaron Held, Andrea Salzinger, Kevin Peikert, Anže Karlek, Hannes Glaß, Dajana Großmann, René Günther, Susanne Petri, Annekathrin Rödiger, David Brenner, Francisco Pan‐Montojo, Eleonora Aronica, Markus Kipp, Vitaly Zimyanin, Jared Sterneckert, Torsten Grehl, Noah D. Seebacher, Tobias M. Böckers, Alberto Catanese, Brian J. Wainger, Patrick Oeckl, Min Ae Lee‐Kirsch, Andreas Hermann   +26 more
wiley   +1 more source

Stellar performance: mechanisms underlying Milky Way orientation in dung beetles. [PDF]

Philos Trans R Soc Lond B Biol Sci, 2017
Foster JJ, El Jundi B, Smolka J, Khaldy L, Nilsson DE, Byrne MJ, Dacke M.   +6 more
europepmc   +1 more source

Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis

Advanced Science, EarlyView.
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang, Yang Hu, Feiyu Wang, Xintao Peng, Honggang Qi, Yuanyuan Yao, Canyu Zhang, Lijie Zhou, Xuemei Liang, Kang Xu, Cong Zhang, Aifeng Zhang, Chen Chen, Yu Zeng, Chenchen Zhang, Guangming Gan, Xinjian Zhu   +16 more
wiley   +1 more source

The habitability of the Milky Way during the active phase of its central supermassive black hole. [PDF]

Sci Rep, 2017
Balbi A, Tombesi F.
europepmc   +1 more source