Results 241 to 250 of about 28,645 (286)

The DNA/RNA autophagy protein SIDT2 as a novel neuropathological hallmark in Huntington disease

Brain Pathology, EarlyView.
SIDT2‐immunoreactive inclusions are observed in the striatum, cerebral cortex, and hypothalamus in HD cases with different Vonsattel grades, and the frequency of SIDT2‐immunoreactive inclusions is associated with longer CAG repeats in the huntingtin gene.
Sanaz Gabery, Sofia Bergh, Chrisovalantou Huridou, Rachel Y. Cheong, Barbara Baldo, Paul Günther Scheunemann, Marie‐Louisa Schoebel, Linda Holmquist Mengelbier, Elisabet Englund, Catriona McLean, Carsten Saft, Deniz Kirik, Maria Björkqvist, Glenda Halliday, Elisabeth Petrasch‐Parwez, Huu Phuc Nguyen, Jonasz Jeremiasz Weber, Åsa Petersén   +17 more
wiley   +1 more source

Enhancing salinity tolerance and growth of Spinacia oleracea L. using halophilic plant growth-promoting bacteria. [PDF]

Sci Rep
Raphael D, Parthasarathi T.
europepmc   +1 more source

Impact of Transnational Family Separation on Parenting and Psychosocial Well‐Being for Black African Migrant Parents in Hamilton

Child &Family Social Work, EarlyView.
ABSTRACT In light of increased migration from sub‐Saharan Africa (SSA) to Hamilton in the past 5 years, this qualitative study explores the experiences of Black African migrant parents resettling in Hamilton, Canada. Using semi‐structured interviews and thematic analysis, four key themes emerged: (1) impact of migration and family separation stress on ...
Tsinat Semagn, Ingrid Waldron, Allison Williams, Olive Wahoush   +3 more
wiley   +1 more source

Bound star clusters observed in a lensed galaxy 460 Myr after the Big Bang. [PDF]

Nature
Adamo A, Bradley LD, Vanzella E, Claeyssens A, Welch B, Diego JM, Mahler G, Oguri M, Sharon K, Abdurro'uf, Hsiao TY, Xu X, Messa M, Lassen AE, Zackrisson E, Brammer G, Coe D, Kokorev V, Ricotti M, Zitrin A, Fujimoto S, Inoue AK, Resseguier T, Rigby JR, Jiménez-Teja Y, Windhorst RA, Hashimoto T, Tamura Y.   +27 more
europepmc   +1 more source

Cosmology and fundamental physics with the ELT-ANDES spectrograph. [PDF]

Exp Astron (Dordr)
Martins CJAP, Cooke R, Liske J, Murphy MT, Noterdaeme P, Schmidt TM, Alcaniz JS, Alves CS, Balashev S, Cristiani S, Di Marcantonio P, Génova Santos R, Gonçalves RS, González Hernández JI, Maiolino R, Marconi A, Marques CMJ, Melo E Sousa MAF, Nunes NJ, Origlia L, Péroux C, Vinzl S, Zanutta A.   +22 more
europepmc   +1 more source

LPC18:0 Secreted by Exogenous Neural Stem Cells Potentiates Neurogenesis and Functional Recovery via GPR55‐Mediated Signalling in Spinal Cord Injury

Cell Proliferation, EarlyView.
LPC18:0 secreted by exogenous neural stem cells potentiates neurogenesis via the GPR55/AKT/GSK3β signalling axis, which ultimately promotes spinal cord injury recovery. ABSTRACT Spinal cord injury (SCI) is a devastating condition with limited therapeutic options. Although neural stem cell (NSC) transplantation shows regenerative potential, its efficacy
Dong Chen, Shuo Liu, Le‐Yi Tu, Ming‐Mei Yang, Cong‐Wang Xu, Yue Jiang, Hui Yang, Chen‐Xu Tai, Yan‐Ning Wang, Yuan‐Yuan Xie, Ping‐Ping Shen, Bin Wang   +11 more
wiley   +1 more source

AMSC‐sEVs Ameliorated Crohn's Disease by Inhibiting Macrophage‐Myofibroblast Transition Through the Delivery of MFGE8

Cell Proliferation, EarlyView.
Our study demonstrated that TGF‐β1 activated MAPK signalling pathway and promoted the MMT and secretion of CCL17 under CD‐associated intestinal inflammatory conditions. AMSC‐sEVs can deliver MFGE8, which inhibits MMT and CCL17‐mediated Treg recruitment by suppressing the MAPK signalling pathway, thereby alleviating intestinal fibrosis.
Minghao Xie, Qiang Liu, Zhizhong Xiong, Jian Li, Ruiri Jin, Lei Lian, Zhengrong Li   +6 more
wiley   +1 more source

Inhibition of Fibroblast Activation Protein‐α Ameliorates Intervertebral Disc Degeneration via Reduced Vascular Invasion in Cartilage Endplate

Cell Proliferation, EarlyView.
Schematic illustration showing that FAP‐α promoted angiogenesis, cytokine release and ECM degradation in the CEP degeneration of the intervertebral disc through upregulating the PI3K/Akt/HIF‐1α/VEGFA pathway. ABSTRACT Intervertebral disc degeneration (IDD) is a primary cause of low back pain, with the development of new blood vessels being a key ...
Hao‐Wei Xu, Sheng‐Jie Chang, Shuo Wang, Xiao‐Wei Liu, Shan‐Jin Wang   +4 more
wiley   +1 more source

Stage‐Associated Microglial Subpopulations and Dynamics in Vascular Pathogenesis of Oxygen‐Induced Retinopathy

Cell Proliferation, EarlyView.
In the oxygen‐induced retinopathy (OIR) mouse model, two distinct microglial subpopulations play opposing roles: highly glycolytic microglia (HGM) promote neovascular formation via Pkm2, while Mrc1/CD206‐positive phagocytosis‐associated microglia (PAM) facilitate its regression.
Yuan Ma, Ziye Chen, Baoyi Liu, Wen Ding, Runping Duan, Kangjie Kong, Zhuojun Xu, Jizhu Li, Jiali Ru, Dianlei Guo, Xiaoyue Wei, Yaping Liu, Zhuangling Lin, Yang Meng, Yuan Liu, Lan Jiang, Zitong Chen, Rebiya Tuxun, Chinling Tsai, Chunqiao Liu, Tao Li   +20 more
wiley   +1 more source

Screening, molecular identification, and evaluation the effects of indigenous Plant Growth-Promoting Rhizobacteria on growth indices and nutrient uptake of chamomile (<i>Matricaria chamomilla</i>) under saline conditions. [PDF]

Front Microbiol
Tafaroji SH, Abtahi SA, Jafarinia M, Ebadi M.   +3 more
europepmc   +1 more source