Results 231 to 240 of about 5,633,642 (286)
In Vitro Screening and Characterization of Feline-Derived Lactic Acid Bacteria as Potential Probiotic Candidates with Bile Salt Hydrolase Activity and Cholesterol-Removal Capacity. [PDF]
Zhang Y +8 more
europepmc +1 more source
Mechanical Activation of Piezo1 Drives Osteoarthritis Through Kdm5c‐Mediated Epigenetic Silencing
Excessive mechanical stress activates Piezo1, triggering Ca2+‐dependent cytoskeletal forces that deform the nucleus and reduce H3K4me3. Kdm5c demethylates H3K4me3 at Col2a1 and Runx3 promoters. Kdm5c knockout rescues degradation. Repurposed telmisartan directly inhibits Kdm5c, blocking this axis and showing disease‐modifying efficacy in mouse OA models
Tianyou Kan +13 more
wiley +1 more source
Upon mitotic entry, RTN4 relocalizes to the pericentrosomal region, forming a more tubular ER network around centrosomes. CDK1‐mediated phosphorylation of RTN4 increases its interaction with Rab11 GTPase, facilitating dynein‐dependent transport of RTN4 to the pericentrosomal region.
Xiangyu Xu +9 more
wiley +1 more source
ABSTRACT Background Treatments for eating disorders (EDs) are often inadequate, and dropout rates are among the highest within psychiatry. The quality of the therapeutic alliance has proven associated with treatment outcome, but forming and maintaining a strong alliance during ED treatment often presents difficulties.
Signe Degn +3 more
wiley +1 more source
Evidence of star cluster migration and merger in dwarf galaxies. [PDF]
Poulain M +10 more
europepmc +1 more source
Impact of A‐/B‐Type Starch Granule Ratios in Reconstituted Wheat Flour on Dough and Bread Properties
ABSTRACT Background and Objectives Wheat starch comprises two granule populations, A‐ and B‐type, whose relative proportions influence the quality of wheat‐based products. In this study, 20% of wheat flour was replaced with blends of starch mixtures (A‐/B‐type ratios 100:0–0:100) and vital wheat gluten to investigate their effects on dough and bread ...
Ah Leum Kim +6 more
wiley +1 more source
Screening of Lactic Acid Bacteria Tolerant to Antimicrobial Substances and Their Effects on the Quality of <i>Cyperus esculentus</i> Silage. [PDF]
Wang H, Liu W, Li S, Jia S, Wang X.
europepmc +1 more source
Untargeted peptide profiling investigates how S. thermophilus, Lb. bulgaricus, and endogenous milk enzymes impact proteolysis during early‐stage milk fermentation. ≥ 3000 identified peptides show the strongest influence of LB on the peptide profile and number of bioactive peptides. Shorter peptides are mostly formed by LB and hydrolyzed by ST.
Eva Beck +6 more
wiley +1 more source
Shared cloud interactions unveil a candidate binary-system supernova pair with no known analogue. [PDF]
Michailidis M +5 more
europepmc +1 more source
Pioglitazone alleviated CLP‐induced sepsis‐associated encephalopathy in mice by activating PPAR‐γ, improving survival, learning, and memory, and anxiety‐like behavior. It also protected the BBB, suppressed TLR4/NF‐κB‐associated inflammation, and reduced neuronal apoptosis, effects largely reversed by GW9662.
Jing Zhang, Peng Wang, Nan Li, Yan Gao
wiley +1 more source

