Results 281 to 290 of about 45,061 (325)

Abundant water from primordial supernovae at cosmic dawn. [PDF]

Nat Astron
Whalen DJ, Latif MA, Jessop C.
europepmc   +1 more source

Aloe‐Emodin Targeting FOXC2 Disrupts NETs Formation and EMT‐Driven Postoperative Peritoneal Adhesion Through TGF‐β1‐Smad2/3 Pathway

Advanced Science, EarlyView.
Forkhead box protein C2 (FOXC2) is highlighted as a pivotal effector in postoperative peritoneal adhesion (PPA) formation. Mechanically, FOXC2 mediates NETs‐induced EMT alterations through the TGF‐β1‐Smad2/3 pathway. Aloe‐emodin (AE) ameliorates FOXC2‐driven fibrosis by blocking NETs formation and EMT changes through this pathway.
Lili Yang, Yunda Fang, Yuheng Lian, Ziyang Kong, Jia Miao, Yanqi Chen, Wen Li, Feiyan Chen, Bin Zhang, Yao Chen, Yaoyao Bian   +10 more
wiley   +1 more source

Thiol-based redox sensing regulates the yellow pigment and antioxidant accumulation and improves the nutritional quality of wheat grains (<i>Triticum aestivum</i> L.). [PDF]

Front Plant Sci
Kumar RR, Babu H P, Hasija S, Gampa M, Goswami S, T V, Kumar S, Mishra GP, Mishra D, Rai GK, Jha GK, Kumar SN, Praveen S, Tyagi A, C V.   +14 more
europepmc   +1 more source

Promoting Autophagy Mitigates Stress‐Induced Remodeling in Patient iPSC‐CMs with the Phospholamban R9C Mutation

Advanced Science, EarlyView.
The Phospholamban (PLN) R9C mutation reduces SERCA2a binding, increasing calcium recycling and baseline contractility. However, the excess of free PLN promotes pentamer formation, limiting phosphorylation and blunting β‐adrenergic signaling. Under cardiac stress, enhanced functional demands overwhelm proteostasis in PLN R9C cells, leading to misfolded ...
Qi Yu, Yawei Shen, Robert J. Barndt, Karim Sallam, Ying Tang, Cameron E. Brown, Xiao Li, Stephen Y. Chan, Joseph C. Wu, Qing Liu, Haodi Wu   +10 more
wiley   +1 more source

An all-sky light pollution model for global-scale applications that embraces a full range of cloud distributions. [PDF]

Proc Natl Acad Sci U S A
Kocifaj M, Falchi F, Kundracik F.
europepmc   +1 more source

Punicalagin Enhances Autophagy Through Sirtuin 1/FoxO3a Axis to Inhibit Intracellular Mycobacterium Abscessus Infection

Advanced Science, EarlyView.
Punicalagin, a pomegranate molecule, helps the body fight Mycobacterium abscessus. It preferentially boosts interstitial macrophages in the lung, stabilizing mitochondria and switching on the autophagy via SIRT1/FoxO3a, which lowers bacterial load without directly killing bacteria.
Kefan Bi, Bihan Xu, Dan Cao, Kaijin Xu, Ying Zhang   +4 more
wiley   +1 more source

Physiological and Biochemical Indicators of Urban Environmental Stress in <i>Tilia</i>, <i>Celtis</i>, and <i>Platanus</i>: A Functional Trait-Based Approach. [PDF]

Plants (Basel)
Arsenov D, Borišev M, Nikolić N, Horak R, Pajević S.   +4 more
europepmc   +1 more source

Analysis of regularity/chaoticity of the Globular ckusters dynamics in the central region of the Milky Way

A.T. Bajkova, A.A. Smirnov, V.V. Bobylev
openalex   +1 more source

Reproductive Characteristics of <i>Odontobutis potamophila</i>: Implications for Sustainable Fisheries Management. [PDF]

Animals (Basel)
Xiang M, Zhao S, Li B, Li L, Wang M, Wang J, Lin R, Zhang L.   +7 more
europepmc   +1 more source

Isolation of Lactic Acid Bacteria from Naturally Ensiled <i>Rosa roxburghii</i> Tratt Pomace and Evaluation of Their Ensiling Potential and Antioxidant Properties. [PDF]

Foods
Pan X, Zhang Y, Yue N, Yu K, Zhou L, Ge L, Chen F, Yang J, Li Q, Deng T, Yang X.   +10 more
europepmc   +1 more source