Results 131 to 140 of about 267,615 (357)

Gut alterations in a chronic kidney disease rat model with diet‐induced vascular calcification

FEBS Open Bio, EarlyView.
Chronic kidney disease (CKD) patients often suffer from intestinal and/or mineral and bone disorders. Using a rat model, we showed that uremic vascular calcification is associated with gut barrier alterations (decreased gut mucus production and Nlrp6 gene expression, increased gut inflammation), and plasma retention of gut‐origin uremic toxins (indoxyl
Piotr Bartochowski, Irene Cortijo, Shruti Bhargava, Bernard Jover, Fabrice Raynaud, Juliana H Boukhaled, Anne‐Dominique Lajoix, Vera Jankowski, Joachim Jankowski, Magali Cordaillat‐Simmons, Àngel Argilés, Nathalie Gayrard, Flore Duranton, Jonas Laget   +13 more
wiley   +1 more source

Disk Heating, Galactoseismology, and the Formation of Stellar Halos

Galaxies, 2017
Deep photometric surveys of the Milky Way have revealed diffuse structures encircling our Galaxy far beyond the “classical” limits of the stellar disk. This paper reviews results from our own and other observational programs, which together suggest that,
Kathryn V. Johnston, Adrian M. Price-Whelan, Maria Bergemann, Chervin Laporte, Ting S. Li, Allyson A. Sheffield, Steven R. Majewski, Rachael S. Beaton, Branimir Sesar, Sanjib Sharma   +9 more
doaj   +1 more source

Star formation in the large Magellanic cloud [PDF]

What role the Large Magellanic Cloud (LMC), a dwarf irregular galaxy, plays in understanding infrared luminous galaxies is discussed. There are two main reasons the LMC may prove helpful.
Harvey, Paul M., Hyland, A. R., Jones, Terry Jay   +2 more
core   +1 more source

4MOST Consortium Survey 3: Milky Way Disc and Bulge Low-Resolution Survey (4MIDABLE-LR)

, 2019
The mechanisms of the formation and evolution of the Milky Way are encoded in the orbits, chemistry and ages of its stars. With the 4MOST MIlky way Disk And BuLgE Low-Resolution Survey (4MIDABLE-LR) we aim to study kinematic and chemical substructures in
Anders, F., Andrae, R., Arentsen, A., Asplund, M., Bensby, T., Bergemann, M., Casagrande, L., Cescutti, G., Chiappini, C., Church, R., Feltzing, S., Fouesneau, M., Fusillo, N., Gerhard, O., Grebel, E., Guiglion, G., Khalatyan, A., Kordopatis, G., Kovalev, M., Lemasle, B., Matijevic, G., McMillan, P., Minchev, I., Monari, G., Queiroz, A., Rix, H., Rybizki, J., Ryde, N., Schwope, A., Starkenburg, E., Steinmetz, M., Storm, J., Team, 4., Traven, G., Tremblay, P., Valentini, M., Walton, N., Xiang, M., Zucker, D.   +38 more
core   +1 more source

Rising from the Ashes: A Metallicity-dependent Star Formation Gap Splits the Milky Way’s α Sequences

The Astrophysical Journal
The elemental abundance distribution of stars encodes the history of the gas-phase abundance in the Milky Way. Without a large, unbiased sample of highly precise stellar ages, the exact timing and nature of this history must be inferred from the ...
Angus Beane
doaj   +1 more source

Neurotoxic amyloid β‐peptide and tau produce cytokine‐like effects on PMCA in glioblastoma cell lines, enhancing its activity and isoforms expression

FEBS Open Bio, EarlyView.
Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal, Alberto Alvarez‐Barrientos, Ana M. Mata   +2 more
wiley   +1 more source

On the Formation of Planets in the Milky Way’s Thick Disk

The Astrophysical Journal
Abstract Exoplanet demographic surveys have revealed that close-in (≲1 au) small planets orbiting stars in the Milky Way’s thick disk are ∼50% less abundant than those orbiting stars in the Galactic thin disk. One key difference between the two stellar populations is the time at which they emerged: thick-disk stars are the likely product
Tim Hallatt, Eve J. Lee
openaire   +3 more sources

The Formation of the Milky Way Nuclear Cluster

, 2011
4 pages, 4 figures, To appear in "Advances in Computational Astrophysics: methods, tools and outcomes", ASP Conference Series, R. Capuzzo-Dolcetta, M. Limongi and A.
Mastrobuono-Battisti, Alessandra, Capuzzo-Dolcetta, Roberto   +1 more
openaire   +2 more sources

True Pair-instability Supernova Descendant: Implications for the First Stars’ Mass Distribution

The Astrophysical Journal Letters
The initial mass function (IMF) of the first Population III (Pop III) stars remains a persistent mystery. Their predicted massive nature implies the existence of stars exploding as pair-instability supernovae (PISNe), but no observational evidence had ...
Ioanna Koutsouridou, Stefania Salvadori, Ása Skúladóttir   +2 more
doaj   +1 more source

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

FEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna, Richard Buchal, Martin Leníček, Amit Shachak, Jan Pláteník   +4 more
wiley   +1 more source