Results 161 to 170 of about 267,615 (357)

HMGB1 Derived from the Pyroptotic Microenvironment Promotes Macrophage Extracellular Traps in Hirschsprung‐Associated Enterocolitis

open access: yesAdvanced Biology, EarlyView.
HMGB1 derived from the pyroptotic environment in Hirschsprung‐associated enterocolitis mediates the formation of macrophage extracellular traps through TLR4 ‐p38 MAPK/p65 NF‐kB signaling pathways. Macrophage extracellular traps induce increased ROS production and pyroptosis of colonic epithelial cells.
Rui Zhang   +6 more
wiley   +1 more source

Fecal Microbiota Transplantation Modulates Th17/Treg Balance via JAK/STAT Pathway in ARDS Rats

open access: yesAdvanced Biology, EarlyView.
Fecal microbiota transplantation (FMT) alleviates lung and intestinal injury in lipopolysaccharide (LPS)‐induced acute respiratory distress syndrome (ARDS) in rats. This study demonstrates that FMT restores the balance between Th17 and Treg cells, inhibits the JAK/STAT pathway, and modulates cytokine levels, reducing inflammation and lung damage. These
Dongwei Zhang   +8 more
wiley   +1 more source

Formation of Milky Way-type stellar haloes in a Λ-CDM cosmology

open access: yesEPJ Web of Conferences, 2012
Recent observations suggest that the Milky Way stellar halo has a ‘dual nature’, meaning that both dissipational and dissipationless processes play a role in its build-up.
Font A.S.
doaj   +1 more source

Galaxias Enanas del Grupo Local

open access: yesMomento, 2009
The satellite galaxies of the Milky Way are very important both for the studies of the formation and evolution of galaxies and for the research on the dark matter problem. In the present review paper some structural properties of the Local Group, as well
A Casallas Lagos   +2 more
doaj  

Time‐Controlled Dual Targeting to Program Systemic and Intercellular Transfer of Therapeutic Effects

open access: yesAdvanced Functional Materials, EarlyView.
Aspirin‐liposomes loaded onto monocytes enable inflammation‐triggered targeting and efficient hand‐over of aspirin to inflamed cells. Monocytes uptake a significant portion of aspirin‐liposomes, prolonging therapeutic action. This approach enhances anti‐inflammatory effects through intercellular transfer, demonstrating a translational strategy for ...
Seung Eun Yu   +6 more
wiley   +1 more source

Stars and star formation in the Milky Way system

open access: yes, 2022
Dwarf galaxies in the Milky Way (MW) system provide us with important information of the star formation in the early Universe. In particular, extremely metal-poor stars in them are likely to form in the environment that is directly influenced by the first stars.
openaire   +2 more sources

Rising from the Ashes. II. The Bar-driven Abundance Bimodality of the Milky Way

open access: yesThe Astrophysical Journal
The Milky Way hosts at least two modes in its present-day distribution of Fe and α -elements. The exact cause of this bimodality is disputed, but one class of explanations involves the merger between the Milky Way and a relatively massive satellite (Gaia-
Angus Beane   +5 more
doaj   +1 more source

Photothermal Hydrogel with Mn3O4 Nanoparticles Alleviates Intervertebral Disc Degeneration by Scavenging ROS and Regulating Extracellular Matrix Metabolism

open access: yesAdvanced Functional Materials, EarlyView.
The MPTT‐nanozyme‐hydrogel system (Mn3O4@ChS‐HA) provides a multifunctional therapeutic strategy for intervertebral disc degeneration (IVDD), effectively targeting oxidative stress and enhancing AF repair by restoring extracellular matrix (ECM) and redox homeostasis.
Yangyang Chen   +13 more
wiley   +1 more source

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