Results 161 to 170 of about 92,409 (330)

Platelet Lysate–Enriched Human Induced Pluripotent Stem Cell–Derived Chondrocyte Sheets for Bone Defect Repair via Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human iPSC‐derived hypertrophic chondrocyte sheet promotes bone regeneration. Abstract Bone defects are a major clinical challenge, primarily owing to the limited self‐healing capacity of bones and the high risk of complications associated with conventional treatment strategies.
Yiwei Chen, Jiali Lin, Jiapeng Li, Yiwei Hu, Jiansen Su, Yu Miao, Lanlan Wang, Qian Tang, Changqing Zhang, Junhui Yin   +9 more
wiley   +1 more source

On the recent star formation history of the Milky Way disk [PDF]

, 2004
R. de la Fuente Marcos, C. de la Fuente Marcos   +1 more
openalex   +1 more source

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

Advanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji, Zengyu Zhang, Zhuohang Liu, Kaicheng Yang, Xueyu Mao, Min Chu, Yong Wang, Jing Zhao   +7 more
wiley   +1 more source

Analysis of enrichment histories for elements and two modes of star formation during the early evolution of Milky Way [PDF]

, 2014
Shimako Yamada, Takuma Suda, Yutaka Komiya, Wako Aoki, Masayuki Y. Fujimoto   +4 more
openalex   +1 more source

Isolation Defines Identity: Functional Consequences of Extracellular Vesicle Purification Strategies

Advanced Healthcare Materials, EarlyView.
Four extracellular vesicle purification strategies are compared using ovarian‐cancer ascites and ES‐2 cell supernatants. A novel workflow links purification to function by combining particle‐normalized proteomics with matched cell‐free and cell‐based assays.
Christian Preußer, Dolores J. Salander, Witold Szymanski, Johannes Graumann, Yukai Wang, Kai Zhao, Jörg W. Bartsch, María Gómez‐Serrano, Daniel Bachurski, Silke Reinartz, Elke von Pogge von Strandmann   +10 more
wiley   +1 more source

The Galactic Bulge Exploration. VI. Gaia Enceladus/Sausage RR Lyrae Stars in the Inner-central Stellar Halo of the Milky Way

The Astronomical Journal
We present a view of the stellar halo in the inner-central regions of the Milky Way ( R ≲ 10 kpc) mapped by RR Lyrae stars. The combined BRAVA-RR/APOGEE RR Lyrae catalog is used to obtain a sample of 281 RR Lyrae stars located in the bulge region of the ...
Andrea Kunder, Zdenek Prudil, Antonela Monachesi, Samuel J. Morris, Kathryn Devine, Joanne Hughes, Kevin R. Covey, R. Michael Rich, Elisa A. Tau   +8 more
doaj   +1 more source

Star cluster formation and feedback in different environments of a Milky Way-like galaxy [PDF]

, 2023
Ahmad A. Ali, Clare L. Dobbs, Thomas J R Bending, Anne S. M. Buckner, Alex R. Pettitt   +4 more
openalex   +1 more source

Low‐Temperature Fabrication of Thymosin β4‐Loaded Soluble Microneedles to Promote Wound Healing by Specific Binding to Downregulated Immune Regulators Vsig4 and IL22rɑ2

Advanced Healthcare Materials, EarlyView.
Schematic diagram depicting the fabrication and application of thymosin β4 (Tβ4)‐loaded microneedle patches for wound treatment. The Tβ4 was loaded into chitosan (CS) and sucrose MNs under mild conditions (4°C, 65% relative humidity). The Tβ4 MN patch specifically binds to the downregulated immune regulators Vsig4 and IL22rα2, thereby accelerating ...
Shilong He, Mei Yuan, Changkang Feng, Yixuan Zhang, Jinjing Che   +4 more
wiley   +1 more source

Formation of Galactic Disks. I. Why Did the Milky Way’s Disk Form Unusually Early?

The Astrophysical Journal
Recent results from spectroscopic and astrometric surveys of nearby stars suggest that the stellar disk of our Milky Way (MW) was formed quite early, within the first few billion years of its evolution.
Vadim A. Semenov, Charlie Conroy, Vedant Chandra, Lars Hernquist, Dylan Nelson   +4 more
doaj   +1 more source

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

Advanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang, Si‐Bo Yang, Yan Luo, Xiao‐Di Sun, Bo‐Hao Chang, Da‐Qiang Zhou, Jun‐Jie Jiang, Ya‐Nan Li, Jie‐Hong Wu, Hui‐Juan Jin, Hang Yang, Hang Hu, Yi‐Fan Zhou, Bo Hu   +13 more
wiley   +1 more source