Results 181 to 190 of about 29,619 (304)
Structure and Kinematics of the Stellar Halos and Thick Disks of the Milky Way Based on Calibration Stars from SDSS DR7 [PDF]
D. Carollo+5 more
openalex +1 more source
In this study, Acod1 knockout in CLP mice significantly increases peripheral blood NET levels, exacerbating inflammation, organ damage, and reducing survival. Further research shows that UBR5 interacts with PAD4, a key NET formation protein. Acod1/itaconate (ITA) enhances the enzymatic activity of UBR5 by alkylating the Cys2768 site, promoting the K48 ...
Huifan Liu+10 more
wiley +1 more source
The radial variation of the LMC-induced reflex motion of the Milky Way disc observed in the stellar halo [PDF]
Rashid Yaaqib+2 more
openalex +3 more sources
Very-metal-poor stars ([Fe/H] < −2) are important laboratories for testing stellar models and reconstructing the formation history of our galaxy. Asteroseismology is a powerful tool to probe stellar interiors and measure ages, but few asteroseismic ...
Daniel Huber+17 more
doaj +1 more source
EVIDENCE FOR A TRIAXIAL MILKY WAY DARK MATTER HALO FROM THE SAGITTARIUS STELLAR TIDAL STREAM [PDF]
David R. Law+2 more
openalex +1 more source
These findings elucidate the innovative role of HIC1 as a transcriptional activator in GC, driving the initiation of pyroptosis and enhancing CD8+ T cell infiltration, which has certain novelty and creative significance. Collectively, targeting HIC1 can present an appealing immunotherapeutic strategy to improve outcomes in GC patients.
Mengjie Kang+4 more
wiley +1 more source
The cosmic ray ionization and γ-ray budgets of star-forming galaxies. [PDF]
Krumholz MR, Crocker RM, Offner SSR.
europepmc +1 more source
IncRNA‐ZFAS1, an Emerging Gate‐Keeper in DNA Damage‐Dependent Transcriptional Regulation
LncZFAS1 plays a crucial role during DNA damage response in mammalian cells. Loss of lncZFAS1 results in deficient DNA lesion removal and reduced cell viability. Mechanistically, lncZFAS1 modulates RNAPII phosphorylation and transcription and thereby promotes both GG‐NER and TC‐NER upon UV damage.
Jiena Liu+10 more
wiley +1 more source
The Hercules Satellite: A Stellar Stream in the Milky Way Halo? [PDF]
Shoko Jin, Nicolas F. Martin
openalex +1 more source
Identifying biomarkers associated with PTC, particularly those related to PTMC progression, is crucial for precise risk stratification and treatment planning. This study utilized single‐cell RNA sequencing on 19 surgical tissue specimens, confirmed PROS1/MERTK axis as a critical component of the cellular microenvironment and a key regulatory mechanism ...
Wenqian Zhang+11 more
wiley +1 more source