Results 1 to 10 of about 4,551 (99)
A Genetic Risk Variant Associated With the Risk of Primary Biliary Cholangitis Is Inherited From Neanderthals. [PDF]
Liver IntABSTRACT Background Primary Biliary Cholangitis (PBC) is an autoimmune cholangiopathy with polygenic architecture and unknown aetiology. Evidence links Neanderthal‐derived genetic variants to autoimmune conditions; however, their contribution to PBC susceptibility remains unexplored.
Gerussi A +22 more
europepmc +2 more sources
Proopiomelanocortin (POMC)–β‐Endorphin System in the Rat Colon: Expression, Up Regulation by Stress, and Correlation With Stress‐Induced Visceral Analgesia [PDF]
Neurogastroenterol MotilThis study identified a functional proopiomelanocortin–β‐endorphin system in the rat colon. Peripheral CRF and repeated water avoidance stress increased colonic POMC expression, which was associated with reduced visceral pain. These findings suggest that, outside the pituitary, a CRF‐ and stress‐sensitive enteric POMC–β‐endorphin system may help ...
Yuan P, Larauche M, Wu V, Taché Y.
europepmc +2 more sources
Animal Models and Experimental Medicine, EarlyView.The pathogenesis of hypoxic pulmonary hypertension (HPH) remains unclear. In this study, we explored its key regulatory mechanisms using animal models, RNA sequencing, and cellular assays. We found that lncRNA‐92467 functions as a ceRNA, binding miR‐205‐5p, and thereby upregulating PTPRM, inhibiting abnormal proliferation and migration of endothelial ...
Yan‐Ying Shen +7 more
wiley +1 more source
Review of the fauna associated with wild and farmed mussels and oysters in the Mediterranean
Biological Reviews, EarlyView.ABSTRACT Mussels and oysters are important ecosystem engineers which modify the physical and chemical characteristics of the environment and create habitats that support highly diverse associated communities. In the Mediterranean Sea, the native Mediterranean mussel Mytilus galloprovincialis and the European flat oyster Ostrea edulis, together the ...
Barbara Mikac +5 more
wiley +1 more source
PLANTS, PEOPLE, PLANET, EarlyView.Sorghum bicolor is a globally important cereal crop with annual yields exceeding 50 million tons across more than 100 countries and can be grown on marginal lands where conventional agriculture is limited. We examined how eight genetically diverse sorghum genotypes shaped arbuscular mycorrhizal fungal (AMF) community assembly across two contrasting ...
Philip Brailey‐Crane +8 more
wiley +1 more source
Sustainable Development, EarlyView.ABSTRACT The FAO's “blue transformation” roadmap necessitates a fundamental shift towards precision aquaculture to meet global food security targets while minimizing environmental footprints. This review provides a comprehensive overview of how artificial intelligence (AI) and decision support systems (DSS) serve as pivotal enablers for the “better ...
Mustafa Öz, Enes Üstüner
wiley +1 more source
Determinants of Community Resilience: A Multi‐Level Synthesis of Empirical and Conceptual Evidence
Sustainable Development, EarlyView.ABSTRACT Community resilience research remains fragmented across disciplines, with limited integration of empirical evidence and conceptual scholarship. This study addresses this gap through a directed content analysis of 48 empirical case studies and 39 conceptual and review publications from diverse geographical and hazard contexts.
Anamol Neupane +2 more
wiley +1 more source
The status quo is imperiled: Acknowledging the issue of range‐shifting wildlife species
Wildlife Society Bulletin, EarlyView.Rapid climate and land‐use change are reshaping wildlife distributions, forcing managers to confront difficult decisions that challenge the traditional “status quo” approach. Range contractions of snow‐dependent species such as the snowshoe hare (Lepus americanus; left photo) may increasingly require practitioners to recognize and plan for unavoidable ...
Brett A. DeGregorio, Leigh Anne Harden
wiley +1 more source
With a Great Story Comes Great Responsibility: Role of Narrative in Leadership Development
New Directions for Student Leadership, Volume 2025, Issue 185, Page 81-87, Spring 2025.ABSTRACT Comic books reside uniquely within American culture. Historians have contended comics are more than just sequential artwork mixed with engaging stories, but rather, a framework by which the generations make sense of who they are. These stories are a reflection of cultural conscience; a lens through which we can view the world and a mirror ...
Sean Connable
wiley +1 more source
Context‐dependent joint buffering of abiotic stress by parental care and sibling interactions
Functional Ecology, EarlyView.Read the free Plain Language Summary for this article on the Journal blog. Abstract Climate change represents one of the most complex challenges of the 21st century, increasing global temperatures and the occurrence of extreme events, such as heatwaves, cold snaps, floods or droughts.
Paul Huber +5 more
wiley +1 more source