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Preclinical pharmacology of milnacipran
International Clinical Psychopharmacology, 1996Milnacipran (Ixel) is a new antidepressant which has been developed for its selective inhibition of both serotonin and noradrenaline reuptake and its lack of affinity for neurotransmitter receptors. It inhibits virtually equipotently the reuptake of serotonin and noradrenaline both in vitro and in vivo, as demonstrated by the antagonism of centrally ...
M, Briley, J F, Prost, C, Moret
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Fatal intoxication with milnacipran
Journal of Forensic and Legal Medicine, 2008The antidepressant milnacipran is a double serotonin/noradrenalin reuptake inhibitor. The low reported incidence of intoxication indicates excellent tolerance in comparison with tricyclic and second generation antidepressants. We report a fatal intoxication associating milnacipran, at blood levels (femoral=21.5 mg/l, cardiac=20 mg/l) 40-fold higher ...
Laurent, Fanton +5 more
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Drugs, 1998
Milnacipran is a cyclopropane derivative which acts by inhibiting noradrenaline (norepinephrine) and serotonin (5-hydroxytryptamine; 5-HT) reuptake at presynaptic sites; no postsynaptic receptor activity has been demonstrated. It is most commonly administered at a dosage of 50 mg twice daily for the treatment of major depressive disorder.
C M, Spencer, M I, Wilde
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Milnacipran is a cyclopropane derivative which acts by inhibiting noradrenaline (norepinephrine) and serotonin (5-hydroxytryptamine; 5-HT) reuptake at presynaptic sites; no postsynaptic receptor activity has been demonstrated. It is most commonly administered at a dosage of 50 mg twice daily for the treatment of major depressive disorder.
C M, Spencer, M I, Wilde
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Psychiatric comorbidities and use of milnacipran in patients with chronic dizziness
Journal of Vestibular Research-Equilibrium & Orientation, 2016BACKGROUND: Psychiatric comorbidities are an important issue in the treatment of chronic dizziness patients. OBJECTIVE: To test the correlation between psychiatric status and subjective handicaps and to examine the effects of milnacipran on handicaps ...
A. Horii +6 more
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Die klinische Anwendung von Milnacipran in Österreich und Deutschland
Nervenheilkunde, 2019Zusammenfassung Milnacipran ist ein Antidepressivum aus der Gruppe der Serotonin-Noradrenalin-Wiederaufnahmehemmer, zu welcher auch Venlafaxin und Duloxetin gehören.
M. Hienert +4 more
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American Journal of Therapeutics, 2019
generally well controlled after switching from DFXDT to DFX-G. This finding indicates that the DFX formulation can be switched without a loss of efficacy if appropriate doses are used.
Ahmed Naguy +3 more
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generally well controlled after switching from DFXDT to DFX-G. This finding indicates that the DFX formulation can be switched without a loss of efficacy if appropriate doses are used.
Ahmed Naguy +3 more
semanticscholar +1 more source
Journal of Drug Delivery Science and Technology, 2022
Zhengge Yang +7 more
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Zhengge Yang +7 more
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