Results 1 to 10 of about 28,372 (298)

Cooperative NHC/Photoredox Catalyzed Ring-Opening of Aryl Cyclopropanes to 1-Aroyloxylated-3-Acylated Alkanes

Angewandte Chemie - International Edition, 2021
Cyclopropanes are an important class of building blocks in organic synthesis. Herein, a ring‐opening/arylcarboxylation/acylation cascade reaction for the 1,3‐difunctionalization of aryl cyclopropanes enabled by cooperative NHC and organophotoredox ...
Armido Studer, Constantin G. Daniliuc, Zhijun Zuo   +2 more
exaly   +2 more sources

Photoredox-catalyzed oxo-amination of aryl cyclopropanes

Nature Communications, 2019
The ring-opening and functionalization of electronically unbiased cyclopropanes is highly challenging to achieve in a regioselective fashion. Here, the authors report a mild photoredox-coupled oxoamination of electronically unactivated aryl cyclopropanes
Liang Ge, Ding-Xing Wang, Renyi Xing, Di Ma, Patrick J. Walsh, Chao Feng   +5 more
doaj   +2 more sources

Divergent synthesis of γ-lactones and cyclopropanes via efficient [1 + 4] and [1 + 2] annulations of amide-sulfoxonium ylides [PDF]

Communications Chemistry
Functionalized γ-lactones and cyclopropanes, especially those bearing amide substituents, play important roles in diverse chemical and pharmacological processes, but their synthesis remains challenging.
Yougen Xu, Haiting Wu, An Lin, Shuang Luo, Lebin Su   +4 more
doaj   +2 more sources

Synthesis of Borylated Orphaned Cyclopropanes through a Boron-Enabled Cycloisomerization Reaction. [PDF]

J Am Chem Soc
Cyclopropanes are important building blocks that are used widely in the pharmaceutical and agrochemical industries. However, synthesizing highly substituted cyclopropanes has proven to be challenging.
Posz JM, Nair AV, Van Hoveln R, Brown MK.   +3 more
europepmc   +2 more sources

Kinetic Studies of Donor–Acceptor Cyclopropanes: The Influence of Structural and Electronic Properties on the Reactivity

Angewandte Chemie - International Edition, 2019
The kinetics of (3+2) cycloaddition reactions of 18 different donor-acceptor cyclopropanes with the same aldehyde were studied by in situ NMR spectroscopy. Increasing the electron density of the donor residue accelerates the reaction by a factor of up to
Daniel B. Werz, Jörg Grunenberg
exaly   +2 more sources

Enantioselective intramolecular cyclopropanation via a cationic sulfoxonium-Rh-carbene [PDF]

Nature Communications
The synthesis of heavily substituted chiral cyclopropanes presents a significant challenge in organic chemistry due to the inherent strain and steric congestion of these three-membered rings.
Yajie Xing, Yuqi Fang, Farshad Shiri, Zhenyang Lin, Jiean Chen, Zhaofeng Wang, Yong Huang   +6 more
doaj   +2 more sources

Highly electrophilic, gem- and spiro-activated trichloromethylnitrocyclopropanes: synthesis and structure [PDF]

Beilstein Journal of Organic Chemistry
New highly electrophilic gem- and spiro-activated trichloromethylnitrocyclopropanes were obtained by the Michael-initiated ring closure (MIRC) reaction of 1-bromo-1-nitro-3,3,3-trichloropropene with linear and cyclic CH-acids catalyzed by bases ...
Ilia A. Pilipenko, Mikhail V. Grigoriev, Olga Yu. Ozerova, Igor A. Litvinov, Darya V. Spiridonova, Aleksander V. Vasilyev, Sergey V. Makarenko   +6 more
doaj   +2 more sources

Thiazolylcyanocyclopropanes: Novel Donor–Acceptor Cyclopropanes for Accessing Thiazole-Containing Targets [PDF]

Molecules
Donor–acceptor (D–A) cyclopropanes are important precursors in the synthesis of complex molecules due to their bidentate character and high reactivity.
Emanuèl Bruno Savini, Edoardo Bandieri, Pietro Pecchini, Nicolò Santarelli, Luca Bernardi, Mariafrancesca Fochi   +5 more
doaj   +2 more sources

Asymmetric [3+2] Photocycloadditions of Cyclopropanes with Alkenes or Alkynes through Visible-Light Excitation of Catalyst-Bound Substrates

Angewandte Chemie - International Edition, 2018
The herein reported visible-light-activated catalytic asymmetric [3+2] photocycloadditions between cyclopropanes and alkenes or alkynes provide access to chiral cyclopentanes and cyclopentenes, respectively, in 63-99 % yields and with excellent ...
Klaus Harms, Paola Ceroni, Xiaoqiang Huang   +2 more
exaly   +2 more sources

A New Golden Age for Donor–Acceptor Cyclopropanes

Angewandte Chemie - International Edition, 2014
Daniel B. Werz, Tobias Schneider, Johannes Kaschel   +2 more
exaly   +2 more sources