Results 41 to 50 of about 9,019 (233)
Transforming cyclopropanes to enamides via σ-C–C bond eliminative borylation
Nature CommunicationsRecent strides in C–H borylation have significantly expanded our toolkit for the preparation of organoboronates. Nevertheless, avenues alternative to obtain these compounds via σ-C–C cleavage, thereby facilitating molecular scaffold editing, remain ...
Shuyu Kang +5 more
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(1RS,3SR)-1-(4-Methylbenzyl)-7-phenyl-5-oxa-6-azaspiro[2.4]hept-6-en-4-one
MolbankThe previously unknown cyclopropane spiro-fused with isoxazol-5-one ((1RS,3SR)-1-(4-methylbenzyl)-7-phenyl-5-oxa-6-azaspiro[2.4]hept-6-en-4-one) was synthesized from benzylideneisoxazol-5-one in 34% yield via double methylene transfer from diazomethane ...
Gleb D. Titov, Nikolai V. Rostovskii
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Access to cyclopropanes with geminal trifluoromethyl and difluoromethylphosphonate groups
Beilstein Journal of Organic Chemistry, 2023 A synthetic route to the bench-stable fluorinated masked carbene reagent diethyl 2-diazo-1,1,3,3,3-pentafluoropropylphosphonate, bearing a trifluoromethyl and a difluoromethyl group is reported for the first time.
Ita Hajdin +5 more
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Angewandte Chemie, EarlyView.Ein verbessertes Niedertemperatur Syntheseverfahren hat die erste umfassende strukturelle und spektroskopische Charakterisierung von neutralem Hexacyanotrimethylencyclopropan (CN6CP) ermöglicht. Kombinierte IR/Raman‐, UV/Vis und ssNMR‐Analysen liefern tiefere Einblicke in die oxidationszustandsabhängige Ladungsverteilung, die σ‐Aromatizität des ...
Jan P. Soyka +8 more
wiley +1 more source
Photochemical preparation of cyclopropanes from cyclobutanones
, 2001 A general method for the preparation of cyclopropanes is reported. Triplet-photosensitized reactions of a series of cyclobutanones give cyclopropanes as the major product.
Edward Lee-Ruff, Jailall Ramnauth
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Dirhodium(II)-catalyzed [3 + 2] cycloaddition of N-arylaminocyclopropane with alkyne derivatives
Beilstein Journal of Organic Chemistry, 2019 Dirhodium(II) complex-catalyzed [3 + 2] reactions between N-arylaminocyclopropanes and alkyne derivatives are described. The cycloaddition products proved to be versatile synthetic intermediates.
Wentong Liu +4 more
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Angewandte Chemie International Edition, EarlyView.An improved low‐temperature synthesis enables the first comprehensive structural and spectroscopic characterisation of neutral hexacyanotrimethylenecyclopropane (CN6CP). Combined IR/Raman, UV–Vis and ssNMR analyses reveal a deeper understanding of its oxidation‐state‐dependent charge redistribution, σ‐aromaticity of the cyclopropane core, and redox ...
Jan P. Soyka +8 more
wiley +1 more source
Computational and mechanistic studies of the acylation of cyclopropanes
, 2016 International audienceAs the well known protonated cyclopropanes' present calculations confirm the existence of acetylated cyclopropanes, we describe the structure of edge- and corner-acetylated cyclopropanes rising from the energetically favored ...
Audran, Gérard +4 more
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Chemistry – A European Journal, EarlyView.The synthesis of 2‐methyl propellane and its conversion to various 1,2‐ and 1,2,3‐di‐ and trisubstituted bicyclopentanes is reported. Abstract Bicyclo[1.1.1]pentanes (BCPs) have emerged as isosteric replacements for mono‐ and para‐substituted benzene rings in medicinal and materials applications, involving substitution at the BCP bridgehead (1,3 ...
Sean R. Verschaeve +4 more
wiley +1 more source
Scalable synthesis of (1-cyclopropyl)cyclopropylamine hydrochloride
Beilstein Journal of Organic Chemistry, 2011 1-Cyclopropylcyclopropanecarboxylic acid (2), which is accessible on a large scale (900 mmol) from 1-bromo-1-cyclopropylcyclopropane (1) in 64% yield (89% on a 12.4 mmol scale), has been subjected to a Curtius degradation employing the Weinstock protocol
Sergei I. Kozhushkov +4 more
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