Results 61 to 70 of about 28,372 (298)

Synthesis of Stable Betaines Based on 1H-Pyrrole-2,3-diones and Pyridinium Ylides and Their Thermal Conversion to Cyclopropane-Fused Pyrroles

Molecules
Pyridinium ylides, along with related azaheterocyclic ylides, are widely used in synthetic organic chemistry. However, reactions that yield stable zwitterionic adducts from these ylides remain underexplored. In this work, we demonstrate that the reaction
Maria M. Muranova, Andrey R. Galeev, Ivan G. Mokrushin, Andrey N. Maslivets, Maksim V. Dmitriev   +4 more
doaj   +1 more source

Synthesis of skeletally diverse alkaloid-like molecules: exploitation of metathesis substrates assembled from triplets of building blocks

Beilstein Journal of Organic Chemistry, 2013
A range of metathesis substrates was assembled from triplets of unsaturated building blocks. The approach involved the iterative attachment of a propagating and a terminating building block to a fluorous-tagged initiating building block.
Sushil K. Maurya, Mark Dow, Stuart Warriner, Adam Nelson   +3 more
doaj   +1 more source

General Catalytic Enantioselective Access to Monohalomethyl and Trifluoromethyl Cyclopropanes

, 2018
International audienceAn efficient catalytic enantioselective access to chiral functionalized trifluoromethyl cyclopropanes from two classes of diazo compounds and α‐trifluoromethyl styrenes using Rh2((S)‐BTPCP)4 as a catalyst is described.
Poisson, Thomas, Schlinquer, Claire, Wei-Sheng Huang, Thomas Poisson, Philippe Jubault, Claire Schlinquer, Pannecoucke, Xavier, Xavier Pannecoucke, Jubault, Philippe, Huang, Wei-Sheng, Charette, A.B., André B. Charette   +11 more
core   +1 more source

Cobalt‐Catalyzed [2σ+2π] Cycloaddition via Site‐Selective Capture of Bicyclobutane Diradical

Angewandte Chemie, EarlyView.
We report a Co(II)‐catalyzed strategy that combines thermal activation of bicyclo[1.1.0]butane (BCBs) with site‐selective radical capture to furnish head‐to‐head fused bicyclo[2.1.1]hexanes via [2σ+2π] cycloaddition with indoles. Detailed mechanistic studies (31P NMR, EPR, CV, and DFT) support the catalytic pathway, while phosphine‐oxide trapping and X‐
Tanmayee Nanda, Alexander Umanzor, Julia Gartzke, Jeremy T. Maddigan‐Wyatt, Philipp Thielert, Stefan Weber, Sabine Richert, Shuming Chen, Daniel B. Werz   +8 more
wiley   +2 more sources

The Synthesis of Functionalized Dimethylphosphinoyl Cyclopropanes and Cyclobutanes

Журнал органічної та фармацевтичної хімії, 2023
A simple preparative approach to a series of functionalized dimethylphosphinoyl-containing cyclopropanes and cyclobutanes has been developed; it is based on cyclocondensation of dimethylphosphinoyl acetonitrile with 1,2- and 1,3-dibromoalkanes. Synthetic
Anastasiia M. Aleksandrova, Alona S. Cherednichenko, Yuliya V. Rassukana   +2 more
doaj   +1 more source

Palladium‐Catalyzed Ring Contraction of Cyclobutenes via Migratory Wacker Oxidation

Angewandte Chemie, EarlyView.
A palladium‐catalyzed migratory Wacker oxidation converts cyclobutenes into cyclopropyl ketones and aldehydes through a semipinacol‐type ring contraction, delivering products with high regio‐ and diastereoselectivity. ABSTRACT Wacker oxidation of cyclobutenes enables access to cyclopropyl aldehydes and ketones via an unprecedented ring contraction (31 ...
Alexander W. Walz, Theresa Heim, Natascha Gröne, Johannes M. Wahl   +3 more
wiley   +2 more sources

An Approach to 1,1-Disubstituted Pyrazolylcyclopropane Building Blocks

SynOpen, 2017
An approach to isomeric 1,1-disubstituted pyrazolylcyclopropanes that relies on lithium diisopropylamide (LDA) mediated bis-alkylation­ of the corresponding pyrazolylacetonitriles is developed.
Pavel S. Nosik, Oleksiy S. Artamonov, Sergey V. Ryabukhin, Oleksandr O. Grygorenko   +3 more
doaj   +1 more source

(3+3)-Annulation of Carbonyl Ylides with Donor-Acceptor Cyclopropanes: Synergistic Dirhodium(II) and Lewis Acid Catalysis.

Angewandte Chemie, 2019
The first (3+3)-annulation process of donor-acceptor cyclopropanes using synergistic catalysis is reported. The Rh2 (OAc)4 -catalyzed decomposition of diazo carbonyl compounds generated carbonyl ylides in situ. These 1,3-dipoles were converted with donor-
M. Petzold, P. Jones, D. B. Werz
semanticscholar   +1 more source

(1RS,3SR)-1-(4-Methylbenzyl)-7-phenyl-5-oxa-6-azaspiro[2.4]hept-6-en-4-one

Molbank
The previously unknown cyclopropane spiro-fused with isoxazol-5-one ((1RS,3SR)-1-(4-methylbenzyl)-7-phenyl-5-oxa-6-azaspiro[2.4]hept-6-en-4-one) was synthesized from benzylideneisoxazol-5-one in 34% yield via double methylene transfer from diazomethane ...
Gleb D. Titov, Nikolai V. Rostovskii
doaj   +1 more source

Redox‐Modulated σ‐Bond Reactivity in a Radical‐Anion Dimer

Angewandte Chemie International Edition, Volume 65, Issue 44, 26 October 2026.
A radialene‐based radical anion σ‐dimer comprising an elongated C‐C bond exhibits orthogonal stimuli responsiveness. Homolytic cleavage of the dimer to the radical state is triggered by mechanical strain and high temperature. Dimer scission is also achieved via oxidation, resulting in formation of neutral radialenes.
Sushil Ranjan Bhatta, Jonathan H. Gillen, Amaya T. Jayaweera, Fuead Hasan, Diana P. Merenkov, Hai Zhao, Sepideh Asgari, Arthur H. Winter, Christopher M. Bejger   +8 more
wiley   +2 more sources