Results 1 to 10 of about 19,839 (247)
Synthesis of Thiadiazoles and 1,2,4-Triazoles Derived from Cyclopropane Dicarboxylic Acid
Molecules, 2005 New heterocyclic derivatives of cyclopropane dicarboxylic acid comprising thiadiazole and 1,2,4-triazole moieties are reported. Reaction of 1,1-cyclopropane dicarboxylic acid (1) with thiosemicarbazide and phosphorous oxychloride resulted in 1,1-bis (2 ...
M. Aouad +3 more
doaj +2 more sources
Ring‐Retentive Allylation of Cyclopropanols Through Interception of Enolized Homoenolates by π‐Allylpalladium [PDF]
Angewandte Chemie, Volume 138, Issue 44, 26 October 2026.Cyclopropanols undergo palladium‐catalyzed, zinc‐mediated allylation with allyl acetates: the ring opens transiently to an enolized homoenolate, is intercepted by π‐allylpalladium, and recloses to furnish β‐allylated cyclopropanols. This formal “allylic cyclopropylation” broadens the reaction space for ring‐retentive functionalization of cyclopropanols.
Kento Tsukiji +2 more
wiley +3 more sources
Enantioselective Access to Trifluoromethylated Spirocyclopropyl Heterocycles [PDF]
Advanced Science, Volume 13, Issue 62, 9 November 2026.We report a rhodium‐catalyzed asymmetric [2+1] spirocyclopropanation of methylene azacycles with trifluoromethyl carbenes in situ derived from fluoroalkyl triftosylhydrazones. ABSTRACT Chiral spirocyclopropyl heterocycles have emerged as privileged three‐dimensional structural motifs in medicinal chemistry.
Yuanhao Zhu +9 more
wiley +2 more sources
Cyclopropylamine‐Derived Distonic Iminium Radicals: Photoinduced Strategies in Chemo‐ and Stereo‐Selective Synthesis [PDF]
Chemistry – A European Journal, Volume 32, Issue 39, 22 October 2026.Cyclopropylamines have emerged as powerful photocatalytic building blocks. Upon light‐induced single‐electron oxidation, they undergo strain‐release ring opening to generate distonic iminium radicals that enable diverse transformations, including ring‐opening functionalization, formal [3 + 2] cycloadditions, radical cascades, and asymmetric bond ...
Maria Chiara Cabua +3 more
wiley +2 more sources
Reactions, 2023 During high-temperature pulse pyrolysis of acyclic butanes and pentanes under adiabatic compression conditions, cyclopropane, a stressed cyclic hydrocarbon, was found among the reaction products in small quantities for the first time. The analysis of the
Igor V. Bilera
doaj +1 more source
Antitumor Profile of Carbon-Bridged Steroids (CBS) and Triterpenoids
Marine Drugs, 2021 This review focuses on the rare group of carbon-bridged steroids (CBS) and triterpenoids found in various natural sources such as green, yellow-green, and red algae, marine sponges, soft corals, ascidians, starfish, and other marine invertebrates.
Valery M. Dembitsky +2 more
doaj +1 more source
Synthesis of Novel C/D Ring Modified Bile Acids
Molecules, 2022 Bile acid receptors have been identified as important targets for the development of new therapeutics to treat various metabolic and inflammatory diseases.
Roselis A. Landaeta Aponte +6 more
doaj +1 more source
Lipophilicity trends upon fluorination of isopropyl, cyclopropyl and 3-oxetanyl groups
Beilstein Journal of Organic Chemistry, 2020 A systematic comparison of lipophilicity modulations upon fluorination of isopropyl, cyclopropyl and 3-oxetanyl substituents, at a single carbon atom, is provided using directly comparable, and easily accessible model compounds.
Benjamin Jeffries +9 more
doaj +1 more source
The Synthesis of Functionalized Dimethylphosphinoyl Cyclopropanes and Cyclobutanes
Журнал органічної та фармацевтичної хімії, 2023 A simple preparative approach to a series of functionalized dimethylphosphinoyl-containing cyclopropanes and cyclobutanes has been developed; it is based on cyclocondensation of dimethylphosphinoyl acetonitrile with 1,2- and 1,3-dibromoalkanes. Synthetic
Anastasiia M. Aleksandrova +2 more
doaj +1 more source
How do Cyclopropane Fatty Acids Protect the Cell Membrane of Escherichia coli in Cold Shock? [PDF]
, 2023 The cyclopropanation of unsaturated lipid acyl chains of some bacterial cell membranes is an important survival strategy to protect the same against drastic cooling.
Archita, Maiti +5 more
core +2 more sources