Results 1 to 10 of about 2,007 (155)

Synthesis of 1,5-Substituted Pyrrolidin-2-ones from Donor–Acceptor Cyclopropanes and Anilines/Benzylamines [PDF]

Molecules, 2022
We developed a straightforward synthetic route to pharmacologically important 1,5-substituted pyrrolidin-2-ones from donor–acceptor cyclopropanes bearing an ester group as one of the acceptor substituents.
Maksim A. Boichenko, Andrey Yu. Plodukhin, Vitaly V. Shorokhov, Danyla S. Lebedev, Anastasya V. Filippova, Sergey S. Zhokhov, Elena A. Tarasenko, Victor B. Rybakov, Igor V. Trushkov, Olga A. Ivanova   +9 more
doaj   +5 more sources

Uncovering the Neglected Similarities of Arynes and Donor–Acceptor Cyclopropanes [PDF]

Angewandte Chemie - International Edition, 2020
Arynes and donor-acceptor (D-A) cyclopropanes are two classes of strained systems having the potential for numerous applications in organic synthesis.
Daniel B Werz, Akkattu T Biju
exaly   +6 more sources

Ferrocenyl-substituted tetrahydrothiophenes via formal [3 + 2]-cycloaddition reactions of ferrocenyl thioketones with donor–acceptor cyclopropanes [PDF]

Beilstein Journal of Organic Chemistry, 2020
Ferrocenyl thioketones reacted with donor–acceptor cyclopropanes in dichloromethane at room temperature in the presence of catalytic amounts of Sc(OTf)3 yielding tetrahydrothiophene derivatives, products of formal [3 + 2]-cycloaddition reactions, in ...
Grzegorz Mlostoń, Mateusz Kowalczyk, André U. Augustin, Peter G. Jones, Daniel B. Werz   +4 more
doaj   +4 more sources

Nickel(II)-Catalyzed Formal [3+2] Cycloadditions between Indoles and Donor–Acceptor Cyclopropanes [PDF]

Molecules
This article describes the development of a nickel-catalyzed regio- and diastereoselective formal [3+2] cycloaddition between N-substituted indoles and donor–acceptor cyclopropanes to synthesize cyclopenta[b]indoles. Optimized reaction conditions provide
Víctor Quezada, Mariña Castroagudín, Felipe Verdugo, Sergio Ortiz, Guillermo Zaragoza, Fabiane M. Nachtigall, Francisco A. A. Reis, Alejandro Castro-Alvarez, Leonardo S. Santos, Ronald Nelson   +9 more
doaj   +4 more sources

Transition-Metal-Free [3+2] Dehydration Cycloaddition of Donor-Acceptor Cyclopropanes With 2-Naphthols [PDF]

Frontiers in Chemistry, 2021
A Brønsted acid-catalyzed domino ring-opening cyclization transformation of donor-acceptor (D-A) cyclopropanes and 2-naphthols has been developed.
Hua Zhao, Peng Shen, Dongru Sun, Hongbin Zhai, Yufen Zhao   +4 more
doaj   +2 more sources

Cycloadditions of Donor–Acceptor Cyclopropanes and ‐butanes using S=N‐Containing Reagents: Access to Cyclic Sulfinamides, Sulfonamides, and Sulfinamidines [PDF]

Angewandte Chemie - International Edition, 2021
Gwyndaf A Oliver, Maximilian N Loch, André U Augustin   +2 more
exaly   +4 more sources

Thiazolylcyanocyclopropanes: Novel Donor–Acceptor Cyclopropanes for Accessing Thiazole-Containing Targets [PDF]

Molecules
Donor–acceptor (D–A) cyclopropanes are important precursors in the synthesis of complex molecules due to their bidentate character and high reactivity.
Emanuèl Bruno Savini, Edoardo Bandieri, Pietro Pecchini, Nicolò Santarelli, Luca Bernardi, Mariafrancesca Fochi   +5 more
doaj   +2 more sources

Palladium-Catalyzed Cascade to Benzoxepins by Using Vinyl-Substituted Donor-Acceptor Cyclopropanes. [PDF]

Angew Chem Int Ed Engl, 2021
Faltracco M, van de Vrande KNA, Dijkstra M, Saya JM, Hamlin TA, Ruijter E.   +5 more
europepmc   +3 more sources

Enantioselective (8+3) Cycloadditions by Activation of Donor-Acceptor Cyclopropanes Employing Chiral Brønsted Base Catalysis. [PDF]

Angew Chem Int Ed Engl, 2022
McLeod DA, Thøgersen MK, Barløse CL, Skipper ML, Obregón EB, Jørgensen KA.   +5 more
europepmc   +3 more sources

(4+3) Annulation of Donor-Acceptor Cyclopropanes and Azadienes: Highly Stereoselective Synthesis of Azepanones. [PDF]

Angew Chem Int Ed Engl, 2022
Nicolai S, Waser J.
europepmc   +3 more sources