Results 31 to 40 of about 2,007 (155)
, 2021 Cyclopropanes bearing donor and acceptor groups at the opposite ends of the C-C bond should react with both nucleophiles and electrophiles. Their reactivity towards nucleophiles is well explored while only few specific electrophilic reagents give desired
Jakub, Durka +3 more
core +1 more source
Bifunctional Photocatalysts: Exploiting Proximity for Enhanced Reaction Performance. [PDF]
ChemistryThis review covers the application of the bifunctional approach to photocatalysis as a means to attain (enhanced) enantioselectivity, and, more in general, as a strategy to enhance the catalytic performance through an effective use of short‐lived reaction intermediates.
Dolcini L +3 more
europepmc +2 more sources
Convenient Synthesis of Functionalized Cyclopropa[c]coumarin-1a-carboxylates
Molecules, 2018 A simple method has been developed for the synthesis of cyclopropa[c]coumarins, which belong to the donor-acceptor cyclopropane family and, therefore, are promising substrates for the preparation of chromene-based fine chemicals. The method, based on the
Olga A. Ivanova +5 more
doaj +1 more source
Nature Communications, 2017 Chiral spirocyclic compounds are important structural motifs for drug discovery. Here, the authors report a synthetic route to spirocycles based on enantioselective cycloaddition of activated spirocyclopropyl oxindoles, which act as donor-acceptor ...
Peng-Wei Xu +6 more
doaj +1 more source
Allylation of Donor−Acceptor Cyclopropanes
, 2016 Direct allylation of glycal-derived donor−acceptor cyclopropanes has been achieved with TiCl4 activation followed by addition of allyltrimethylsilane. The α diastereomer is the major product, with selectivities ranging from 3:1 to 10:1 and yields around ...
Ming Yu (78996) +1 more
core +2 more sources
CHIMIA, 2011 One of the major challenges faced by organic chemistry is the efficient synthesis of increasingly complex molecules. Since October 2007, the Laboratory of Catalysis and Organic Synthesis (LCSO) at EPFL has been working on the development of ...
Davinia Fernández González +4 more
doaj +1 more source
Methods for the synthesis of donor-acceptor cyclopropanes
, 2018 The interest in cyclopropane derivatives is caused by the facts that, first, the three-carbon ring is present in quite a few natural and biologically active ...
Leonid G. Menchikov +4 more
core +3 more sources
Cyclization of Cyclopropyl Carbonyls and the Homo-Nazarov Reaction
CHIMIA, 2009 Ring strain confers exceptional reactivity to the cyclopropane ring. Nevertheless, activation of the cyclopropane ring is usually needed to allow ring-opening reactions under mild conditions.
Filippo De Simone, Jérôme Waser
doaj +1 more source
4b,5,6,9-Tetrahydro-7H-dibenzo[c,e]pyrrolo[1,2-a]azepin-7-one
Molbank, 2019 A simple approach to synthesize 4b,5,6,9-tetrahydro-7H-dibenzo[c,e]pyrrolo[1,2-a]azepin- 7-one has been developed, based on a three-step transformation of 2-(2-bromophenyl)cyclopropane-1,1-diester.
Maksim A. Boichenko +5 more
doaj +1 more source
, 2023 Saturated 1,4-diazocanes are highly important for medicinal chemistry and drug discovery, but their syntheses are often tedious. Herein, we report a copper-catalyzed (5 + 3) annulation of donor–acceptor cyclopropanes with imidazolidines, thereby ...
Shiyong Peng (1508452) +7 more
core +3 more sources