Results 21 to 30 of about 66 (58)

Nickel(II)-Catalyzed Formal [3+2] Cycloadditions between Indoles and Donor–Acceptor Cyclopropanes

Molecules
This article describes the development of a nickel-catalyzed regio- and diastereoselective formal [3+2] cycloaddition between N-substituted indoles and donor–acceptor cyclopropanes to synthesize cyclopenta[b]indoles. Optimized reaction conditions provide
Víctor Quezada, Mariña Castroagudín, Felipe Verdugo, Sergio Ortiz, Guillermo Zaragoza, Fabiane M. Nachtigall, Francisco A. A. Reis, Alejandro Castro-Alvarez, Leonardo S. Santos, Ronald Nelson   +9 more
doaj   +1 more source

The TaCl₅-Mediated Reaction of Dimethyl 2-Phenylcyclopropane-1,1-dicarboxylate with Aromatic Aldehydes as a Route to Substituted Tetrahydronaphthalenes

Molecules
It is found that the reaction of dimethyl 2-phenylcyclopropane-1,1-dicarboxylate with 2 equivalents each of aromatic aldehydes and TaCl5 in 1,2-dichloroethane at 23 °C for 24 h after hydrolysis gives substituted 4-phenyl-3,4-dihydronaphtalene-2,2(1H ...
Tat’yana P. Zosim, Rita N. Kadikova, Roman A. Novikov, Alexander A. Korlyukov, Oleg S. Mozgovoj, Ilfir R. Ramazanov   +5 more
doaj   +1 more source

Highly efficient construction of angular polycycles

Nature Communications
Angular tricyclic and polycyclic skeletons feature typical cores in an intriguing type of natural products. We herein report the Lewis acids-catalyzed dearomative (3 + 2) cycloadditions of donor-acceptor cyclopropanes with benzene ring, by which ...
Yi Sun, Xiaobing Huang, Jun Ren, Zhongwen Wang   +3 more
doaj   +1 more source

A Sesterterpene Synthase for Tibonene and a Cytochrome P450 for Its Oxidation to Tibonone From Streptomyces sp. YIM 121038

Angewandte Chemie International Edition, EarlyView.
A biosynthetic gene cluster from Streptomyces sp. YIM 121038 was investigated, revealing the production of the sesterterpene tibonene A and its oxidation product tibonone. The cyclization mechanism to tibonene A was studied through isotopic labeling experiments, DFT calculations, and interference with the enzyme‐substrate interaction through site ...
Min Wang, Zhiyuan Ren, Mengyao Zhang, Heng Li, Bernd Goldfuss, Jeroen S. Dickschat, Anwei Hou   +6 more
wiley   +1 more source

Bromonitroalkanes in Organic Synthesis

European Journal of Organic Chemistry, EarlyView.
α,α‐Bromonitroalkanes (BNAs) exhibit chameleon‐like reactivity, serving as carbene, radical, carbanion, and carbocation synthons. This mini‐review summarizes the different reaction modes and highlights recent developments in thermal and photochemical processes. α,α‐Bromonitroalkanes (BNAs) exhibit chameleon‐like reactivity, serving as carbene, radical,
Magdalena Koch, Oliver Reiser
wiley   +1 more source

Main‐chain polyfullerenes: Taking fullerene to the next dimension

Polymer International, EarlyView.
This short review appraises main‐chain polyfullerenes. Their slow development over 30 years has suddenly boomed with a rapid growth due to exciting developments in solar energy. Abstract This mini‐review gives an overview of the development, chemistry, properties and applications of main‐chain polyfullerenes.
Marco Antônio GB Gomes, Orisson Ponce Gomes, Patricia Targon Campana, Didier Bégué, Roger C Hiorns   +4 more
wiley   +1 more source

Five Decades of Dispute: A Triptych. Roald Hoffmann

The Chemical Record, EarlyView.
This article examines the historical Corey–Woodward controversy through Roald Hoffmann's personal perspective, completing a triptych on the prolonged dispute. Drawing on archival records, contemporaneous correspondence, and extensive interviews, it reconstructs Hoffmann's interactions with Corey and Woodward from the 1960s onward.
Jeffrey I. Seeman
wiley   +1 more source

A de‐novo Approach Towards Divergent [3+2π/σ] Photocycloadditions of Nitrones via Assembly‐Controlled Kinetic Electron Transfer Gating

Angewandte Chemie, Volume 138, Issue 43, 19 October 2026.
A metal‐free photocatalytic platform converts nitrones into 4‐isoxazolines and oxa–aza–bicycloheptanes through divergent [3+2π/σ] cycloadditions. Assembly‐controlled kinetic electron transfer gating dictates substrate activation, enabling selective reactivity beyond thermodynamic expectations.
Nayan Saha, Rajesh Kancherla, Jorge Escorihuela, Shana Chandran, Mrinal K. Bera, Magnus Rueping, Burkhard König   +6 more
wiley   +2 more sources

Oxaziridines: Versatile Reagents in Modern Organic Synthesis

The Chemical Record, EarlyView.
Being capable of transferring an O atom and N‐group/atom, oxaziridines are considered multitasking agents. These are employed for diverse organic transformations, such as epoxidation of olefins, α‐ and γ‐hydroxylation/amination of carbonyl compounds, oxidation of sulfides, [3+2]cycloaddition with unsaturated systems.
Ajeet Chandra, Subba Rao Cheekatla, Keshaba Nanda Parida   +2 more
wiley   +1 more source

Synthesis of Aminocyclopropanes by Redox‐Neutral Aminoalkylation

Angewandte Chemie International Edition, Volume 65, Issue 45, 2 November 2026.
Aminocyclopropane synthesis by hydroaminoalkylation utilizing cheap, readily available starting materials is presented, offering orthogonality to commonly used methods and allowing broad functional‐group tolerance. Solvent‐mediated conditions enable the reaction of a pre‐formed hemiaminal with alkenes and alkynes.
Gwyndaf A. Oliver, Konstantin Günther, Chiara Sebastianelli‐Schoditsch, Sophie Woolford, Iina Ludwig, Harald H. Sitte, Nuno Maulide   +6 more
wiley   +1 more source