Results 21 to 30 of about 9,019 (233)
Continuous-Flow Synthesis of Arylthio-Cyclopropyl Carbonyl Compounds
Molecules, 2022 The straightforward, continuous-flow synthesis of cyclopropyl carbaldehydes and ketones has been developed starting from 2-hydroxycyclobutanones and aryl thiols.
Davide Moi +10 more
doaj +1 more source
Trifunktionelle Cyclopropane als Vorstufen von Triafulven und Calicen
CHIMIA, 1981 A series of 1,1-dihalo-2-X-cyclopropanes 3 have been prepared and characterised. Cyclopropanes of type 3 could be of interest as starting materials with respect to the attempted synthesis of triafulvene and calicene.
Andreas Weber +3 more
doaj +1 more source
, 2023 Herein, we report a Rh-catalyzed carbofluorination of alkenes using gem-difluorinated cyclopropanes as bifunctional reagents. The developed method tolerates a wide range of alkenes, providing access to secondary, tertiary fluorides and gem-difluorides ...
Ying, Xia +5 more
core +1 more source
, 2021 Chiral cis-cyclopropanes are strained rigid analogs of alkyl chains, whose study and application is still limited by their difficult synthesis. A modular approach for the synthesis of this challenging structures from abundant olefins is enabled by the ...
Matteo, Costantini, Abraham, Mendoza
core +1 more source
Activation and Functionalization of C–C σ-Bonds of Alkylidene Cyclopropanes at Main Group Centers [PDF]
, 2020 Aluminum(I) and magnesium(I) compounds are reported for the C–C s-bond activation of strained alkylidene cyclopropanes. These reactions result in the formal addition of the C–C s-bond to main group center either at a single site (Al) or across a metal ...
Mark, Crimmin +5 more
core +1 more source
, 2021 Cyclopropanes bearing donor and acceptor groups at the opposite ends of the C-C bond should react with both nucleophiles and electrophiles. Their reactivity towards nucleophiles is well explored while only few specific electrophilic reagents give desired
Jakub, Durka +3 more
core +1 more source
Ring-Opening Hydroarylation of Monosubstituted Cyclopropanes Enabled by Hexafluoroisopropanol
, 2018 Ring-opening hydroarylation of cyclopropanes is typically limited to substrates bearing a donor-acceptor motif. Here, the transformation is achieved for monosubstituted cyclopropanes by using catalytic Brønsted acid in hexafluoroisopropanol (HFIP ...
Christopher, Rowley +5 more
core +2 more sources
Angewandte Chemie, EarlyView.A catalytic network embedding a formal rearrangement enables the first catalytic enantioselective multicomponent reaction (MCR) of sulfur ylides. In the presence of a bulky chiral phosphoric acid, the reaction combines sulfoxonium ylides, aldehydes and thiols, and affords synthetically versatile β‐hydroxy‐α‐sulfanyl carbonyl compounds in ...
Nicolò Santarelli +10 more
wiley +2 more sources
Catalytic Functionalization of Unactivated π‐Bonds Enabled by Bidentate Directing Auxiliaries
Angewandte Chemie, EarlyView.This review explores how bidentate directing auxiliaries have advanced transition‐metal catalysis for unactivated alkene/alkyne functionalization. By leveraging chelated intermediates, bidentate directing auxiliaries enable precise hydrofunctionalization, difunctionalization, and C─H activation of π‐bonds with unique selectivity and reactivity.
Seunghyeon Cho +4 more
wiley +2 more sources
‐Containing Trisubstituted Cyclopropanes [PDF]
, 2021 The difluoromethyl (CHF2) group has attracted significant attention in drug discovery and development efforts, owing to its ability to serve as fluorinated bioisostere of methyl, hydroxyl, and thiol groups.
Decaens, Jonathan +9 more
core +1 more source