Results 11 to 20 of about 9,019 (233)

Highly electrophilic, gem- and spiro-activated trichloromethylnitrocyclopropanes: synthesis and structure [PDF]

Beilstein Journal of Organic Chemistry
New highly electrophilic gem- and spiro-activated trichloromethylnitrocyclopropanes were obtained by the Michael-initiated ring closure (MIRC) reaction of 1-bromo-1-nitro-3,3,3-trichloropropene with linear and cyclic CH-acids catalyzed by bases ...
Ilia A. Pilipenko, Mikhail V. Grigoriev, Olga Yu. Ozerova, Igor A. Litvinov, Darya V. Spiridonova, Aleksander V. Vasilyev, Sergey V. Makarenko   +6 more
doaj   +2 more sources

Thiazolylcyanocyclopropanes: Novel Donor–Acceptor Cyclopropanes for Accessing Thiazole-Containing Targets [PDF]

Molecules
Donor–acceptor (D–A) cyclopropanes are important precursors in the synthesis of complex molecules due to their bidentate character and high reactivity.
Emanuèl Bruno Savini, Edoardo Bandieri, Pietro Pecchini, Nicolò Santarelli, Luca Bernardi, Mariafrancesca Fochi   +5 more
doaj   +2 more sources

Enantioselective intramolecular cyclopropanation via a cationic sulfoxonium-Rh-carbene [PDF]

Nature Communications
The synthesis of heavily substituted chiral cyclopropanes presents a significant challenge in organic chemistry due to the inherent strain and steric congestion of these three-membered rings.
Yajie Xing, Yuqi Fang, Farshad Shiri, Zhenyang Lin, Jiean Chen, Zhaofeng Wang, Yong Huang   +6 more
doaj   +2 more sources

Synthesis of Stable Betaines Based on 1H-Pyrrole-2,3-diones and Pyridinium Ylides and Their Thermal Conversion to Cyclopropane-Fused Pyrroles [PDF]

Molecules
Pyridinium ylides, along with related azaheterocyclic ylides, are widely used in synthetic organic chemistry. However, reactions that yield stable zwitterionic adducts from these ylides remain underexplored. In this work, we demonstrate that the reaction
Maria M. Muranova, Andrey R. Galeev, Ivan G. Mokrushin, Andrey N. Maslivets, Maksim V. Dmitriev   +4 more
doaj   +2 more sources

Photoredox-catalyzed cyclopropanation of allenes towards vinyl-cyclopropanes. [PDF]

Chem Sci
Visible-light photoredox-catalyzed regioselective radical-polar crossover cyclization (rRPCC) of terminal and internal allenes with carboxylic acids, access to functionalized vinyl cyclopropanes (VCPs).
Xie H, Zhang Y, Breit B.
europepmc   +3 more sources

Reactivity of electrophilic cyclopropanes [PDF]

, 2023
Cyclopropanes that carry an electron-accepting group react as electrophiles in polar, ring-opening reactions. Analogous reactions at cyclopropanes with additional C2 substituents allow one to access difunctionalized products. Consequently, functionalized
Armin R. Ofial, Ofial, Armin R., Eitzinger, Andreas, Andreas Eitzinger   +3 more
core   +1 more source

Conformationally Fixed Chiral Bisphosphine Ligands by Steric Modulators on the Ligand Backbone: Selective Synthesis of Strained 1,2-Disubstituted Chiral cis-Cyclopropanes

, 2022
A new series of C1-symmetric P-chirogenic bisphosphine ligands of the type (R)-5,8-Si-Quinox-tBu3 (Silyl = SiMe3, SiEt3, SiMe2Ph) have been developed. The bulky silyl modulators attached to the ligand backbone fix the phosphine substituents to form rigid
Hiroaki Iwamoto (1677070), Yuta Hayashi (8394579), Hajime Ito (1441426), Yu Ozawa (4470139), Tsuneo Imamoto (1357569)   +4 more
core   +2 more sources

Synthesis of (Het)aryl 2-(2-hydroxyaryl)cyclopropyl Ketones

Molecules, 2020
A simple general method for the synthesis of 1-acyl-2-(ortho-hydroxyaryl)cyclopropanes, which belong to the donor–acceptor cyclopropane family, has been developed.
Alexander A. Fadeev, Alexey O. Chagarovskiy, Anton S. Makarov, Irina I. Levina, Olga A. Ivanova, Maxim G. Uchuskin, Igor V. Trushkov   +6 more
doaj   +1 more source

Synthesis of 1,5-Substituted Pyrrolidin-2-ones from Donor–Acceptor Cyclopropanes and Anilines/Benzylamines

Molecules, 2022
We developed a straightforward synthetic route to pharmacologically important 1,5-substituted pyrrolidin-2-ones from donor–acceptor cyclopropanes bearing an ester group as one of the acceptor substituents.
Maksim A. Boichenko, Andrey Yu. Plodukhin, Vitaly V. Shorokhov, Danyla S. Lebedev, Anastasya V. Filippova, Sergey S. Zhokhov, Elena A. Tarasenko, Victor B. Rybakov, Igor V. Trushkov, Olga A. Ivanova   +9 more
doaj   +1 more source

Organocatalytic activation of cyclopropanes in asymmetric synthesis

Tetrahedron Chem, 2023
Cyclopropanes are strained carbocycles that can undergo ring opening reactions in which one of the C–C bond present in the cycle is broken following a radical or ionic mechanism.
Efraím Reyes, Uxue Uria, Liher Prieto, Luisa Carrillo, Jose L. Vicario   +4 more
doaj   +1 more source