Results 71 to 80 of about 2,292 (165)

Treatment of Haemophilia A Without Inhibitors: Real‐World Treatment Patterns and Clinical Outcomes in the US

Haemophilia, EarlyView.
ABSTRACT Introduction Despite available prophylactic therapies for haemophilia A, breakthrough bleeding and consequent pain and joint damage still occur. Aim To provide insights into the unmet treatment needs of people with moderate‐to‐severe haemophilia A in the US.
Allison P. Wheeler, Lauren E. Amos, Shveta Gupta, Sylvie Bozzi, Gandarvaka Miles, Kalyani Hawaldar, Andrew Wilson, Gillian Hanson, Emily Cibelli, Amanda Wilson, Siddhi Umarje, Anne‐Laure Tardy, Jennifer Dumont, Graham Neill, Alix Arnaud   +14 more
wiley   +1 more source

Institutional Logics and Relational Inequality in UK Surgery: Demographic Dominance and the Uneven Governance of Careers

Journal of Management Studies, EarlyView.
Abstract Persistent gender and racial inequalities within elite professions remain inadequately explained by accounts focusing exclusively on either intra‐organizational processes or field‐level institutional dynamics. Relational inequality theory (RIT) provides a powerful account of closure within organizations but offers limited specification of how ...
Carol Woodhams, Ira Parnerkar
wiley   +1 more source

Mixed‐methods research in medical education: Lessons from a meta‐study of methodological practice

Medical Education, EarlyView.
Abstract Introduction Mixed‐methods research (MMR) intentionally combines (variously) theories, study designs, data collection, analyses and/or syntheses associated with more than one approach to research. Despite a rich literature on the theory and practice of MMR, the authors were concerned that much MMR in medical education fell short of the state ...
Jennifer Cleland, Anna MacLeod, Susan van Schalkwyk, Rachel H. Ellaway   +3 more
wiley   +1 more source

Alleviating Adjoint Solver Robustness Issues Via Mimetic Cfd Discretization Schemes

, 2014
Adjoint methods allow to compute the gradient of a cost function at an expense that is independent of the number of design variables, thus representing an appealing tool to those who deal with large-scale gradient-based optimization processes. However, researchers in the field are currently facing difficulties related to poor convergence and high ...
Oriani, M.,, Pierrot, G.,
openaire   +1 more source

A Systematic Review and Meta‐Analysis of Semaglutide Effects on Adipose Tissue and Emerging Effects on Brain and Cognition

Obesity Reviews, EarlyView.
ABSTRACT Background In 2023 and 2024, research into semaglutide (SEMA), an antiobesity and antidiabetic medication, indicated potential benefits beyond its approved uses, particularly in preventing Alzheimer's disease (AD). This highlights the link between obesity and AD development.
Amene Saghazadeh, Mahsa Dolatshahi, Soheil Mohammadi, Sara Hosseinzadeh Kassani, Mahshid Naghashzadeh, Joseph E. Ippolito, Claude B. Sirlin, Bettina Mittendorfer, Matthew R. Brier, Suzanne E. Schindler, John C. Morris, Danny Mou, Hani Charles Soudah, Tammie L. S. Benzinger, Cyrus A. Raji   +14 more
wiley   +1 more source

Periods, Pains, Pills, and Performance—Fighting Blood, Bodies and Biology

Sociological Forum, EarlyView.
ABSTRACT This paper draws on various data from long‐term immersion in combat sports to explore the period experiences of cis women fighters. We blend theoretical ideas from the social scientific literature on menstruation and the sociology of medicalization, pain and injury.
Reem AlHashmi, Debra Forbes, Christopher R. Matthews   +2 more
wiley   +1 more source

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

The Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò, Miguel Martín‐Aragón Baudel, Charlotte E. R. Smith, Gonzalo Hernandez Hernandez, Donald M. Bers, Patrick M. Boyle, Dobromir Dobrev, Shanna Hamilton, Osama F. Harraz, Na Li, Thomas A. Longden, William E. Louch, Madeline Nieves‐Cintron, Matthew A. Nystoriak, Walter Lee Murfee, Przemysław B. Radwański, Swapnil K. Sonkusare, Manuel F. Navedo, Eleonora Grandi   +18 more
wiley   +1 more source

Hemodynamic Responses to Word Forms in Japanese Infant‐Directed Vocabulary in 5‐ and 9‐Month‐Old Infants: Early Sensitivity to Prosodic Structure and Emergence of Prosodic Representations

Developmental Science, Volume 29, Issue 4, July 2026.
ABSTRACT The prosodic characteristics of a native language greatly influence early language acquisition. Yet, Japanese mothers are known to use a specific prosodic structure in infant‐directed vocabulary (IDV)—specifically, three‐mora, two‐syllable words with a heavy‐light pattern—which, crucially, differs from the standard prosodic rhythm of adult ...
Yoritaka Akimoto, Miki Takahasi, Naoto Yamane, Rachel Ka‐Ying Tsui, Akiko Hayashi, Reiko Mazuka   +5 more
wiley   +1 more source

Efficient Numerical Framework for Geothermal Energy Production Optimization in Fracture‐Controlled Reservoirs

International Journal for Numerical Methods in Fluids, Volume 98, Issue 6, Page 709-730, June 2026.
We introduce an efficient open‐source numerical framework for the automated search for the placements of injection and production wells in hot fracture‐controlled reservoirs that sustainably optimize geothermal energy production. We model the reservoirs as discrete fracture networks in 3D. The fluid flow and heat transport in the reservoirs are modeled
Ondřej Pártl, Ernesto Meneses Rioseco
wiley   +1 more source

Mimetic Neural Networks: A Unified Framework for Protein Design and Folding. [PDF]

Front Bioinform, 2022
Eliasof M, Boesen T, Haber E, Keasar C, Treister E.   +4 more
europepmc   +1 more source