Results 51 to 60 of about 2,292 (165)

Bifunctional Artificial Enzymes‐Loaded Microgels With LOX‐ and CAT‐Like Activities for Metabolic Reprogramming and Scarless Wound Repair

open access: yesAdvanced Science, EarlyView.
A bifunctional lactate oxidase‐like and catalase‐like artificial enzyme (Metazyme) is integrated into a rod‐shaped microgel (MetaRgel) to enable cascade lactate oxidation and oxygen regeneration. By reprogramming the wound metabolic microenvironment, MetaRgel alleviates excessive lactate accumulation, oxidative stress, hypoxia, and inflammation ...
Yongyuan Kang   +9 more
wiley   +1 more source

All‐in‐One Underwater Quality Evaluation Metamaterial With Mechanical Robustness, Sound Attenuation, and Diffuse Reflection

open access: yesAdvanced Science, EarlyView.
In this work, a bioinspired all‐in‐one underwater quality evaluation metamaterial, combining sound attenuation, diffuse reflection, and mechanical robustness, is proposed based on jumping spider locomotion and human skeletal biomechanics. Meanwhile, a CNN‑driven quality evaluation framework is established for theoretically dimension‐reduced ...
Hongze Li   +8 more
wiley   +1 more source

An agglomeration-based massively parallel non-overlapping additive Schwarz preconditioner for high-order discontinuous Galerkin methods on polytopic grids

open access: yes, 2019
In this article we design and analyze a class of two-level non-overlapping additive Schwarz preconditioners for the solution of the linear system of equations stemming from discontinuous Galerkin discretizations of second-order elliptic partial ...
Antonietti, P. F.   +3 more
core   +1 more source

Dynamic Self‐Clickable Decellularized Matrix Hydrogels for Regulating Vascularity and Enhancing Muscle Regeneration

open access: yesAdvanced Science, EarlyView.
Dynamic decellularized hydrogels are prepared using bovine decellularized small intestine submucosa (SIS) norbornene (dSIS‐NB). Bovine dSIS contained significant amounts of disulfide‐rich fibrillin‐I, enabling ‘self‐clickable’ thiol‐norbornene gelation and spatiotemporal tuning of hydrogel physicochemical properties.
Van Thuy Duong   +4 more
wiley   +1 more source

Multi-functional variational porosity in bone tissue scaffolds [PDF]

open access: yes, 2012
Commonly used homogeneous scaffolds do not capture the intricate spatial material concentration presented in bone internal architecture. On the other hand gradient in porosity along the internal scaffold architecture might contribute for performing ...
Khoda, AKM Bashirul   +2 more
core  

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

A mimetic discretization of Westervelt's equation

open access: yes
A broad class of nonlinear acoustic wave models possess a Hamiltonian structure in their dissipation-free limit and a gradient flow structure for their dissipative dynamics. This structure may be exploited to design numerical methods which preserve the Hamiltonian structure in the dissipation-free limit, and which achieve the correct dissipation rate ...
Barham, William, Morrison, Philip J.
openaire   +2 more sources

Heterogenous Model of Temozolomide Resistance in Glioblastoma Reveals Phenotypic Shifts in Drug Response and Migratory Potential

open access: yesAdvanced NanoBiomed Research, EarlyView.
Glioblastoma mortality is driven by cell invasion and therapeutic resistance. We report a cancer engineering approach to evaluate the behavior of heterogeneous cohorts of temozolomide resistant and responsive GBM cells. We show the effect of physiologically‐relevant metronomic dosing on ensemble drug response and invasion.
Victoria A. Kriuchkovskaia   +5 more
wiley   +1 more source

An HMM--ELLAM scheme on generic polygonal meshes for miscible incompressible flows in porous media

open access: yes, 2018
We design a numerical approximation of a system of partial differential equations modelling the miscible displacement of a fluid by another in a porous medium.
Cheng, Hanz Martin, Droniou, Jerome
core   +1 more source

Patterns of interspecific variation in labial microarchitecture among anthropoid primates and the evolution of the hominin lips

open access: yesThe Anatomical Record, EarlyView.
Comparative histological and semi‐automated image analysis of primate lips: Masson's trichrome‐stained sagittal sections were segmented to quantify the connective tissue, adipose, and muscular components, enabling interspecific comparisons of labial architecture.
Liat Rotenstreich   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy