Results 41 to 50 of about 15,467 (159)

A Hydrogen‐Releasing Nanozyme Engineers a Mitochondrial ROS Amplifier for Self‐Sustaining Catalytic Immunotherapy

open access: yesAdvanced Science, EarlyView.
We developed a RhPd‐H nanozyme that integrates enhanced POD‐mimetic catalytic activity with thermally triggered H2 release. H2 shields and reprograms mitochondria to continuously leak endogenous ·O2−. This dual‐path ROS spatially and temporally disrupts redox homeostasis, inducing persistent oxidative stress for tumor suppression and antitumor immunity,
Mingfan Shi   +12 more
wiley   +1 more source

Virtual Element Methods for hyperbolic problems on polygonal meshes [PDF]

open access: yes, 2016
In the present paper we develop the Virtual Element Method for hyperbolic problems on polygonal meshes, considering the linear wave equations as our model problem. After presenting the semi-discrete scheme, we derive the convergence estimates in H^1 semi-
Vacca, Giuseppe
core   +1 more source

Temporal Interference Stimulation Enhances Neural Regeneration

open access: yesAdvanced Science, EarlyView.
Temporal interference (TI) stimulation is proposed as a non‐invasive approach to enhance neural regeneration in the deep brain. Theta‐band TI modulation selectively promotes neural progenitor cell differentiation in vitro and augments hippocampal neurogenesis in amouse model of Alzheimer's disease‐like amyloidosis.
Sofia Peressott   +15 more
wiley   +1 more source

Mimetic finite differences for nonlinear and control problems

open access: yesMathematical Models and Methods in Applied Sciences, 2014
In this paper we review some recent applications of the mimetic finite difference method to nonlinear problems (variational inequalities and quasilinear elliptic equations) and optimal control problems governed by linear elliptic partial differential equations. Several numerical examples show the effectiveness of mimetic finite differences in building
ANTONIETTI, PAOLA FRANCESCA   +3 more
openaire   +4 more sources

Parametric Analysis of Spiking Neurons in 16 nm Fin Field‐Effect Transistor Technology

open access: yesAdvanced Intelligent Discovery, EarlyView.
Energy efficient computing has driven a shift toward brain‐inspired neuromorphic hardware. This study explores the design of three distinct silicon neuron topologies implemented in 16 nm fin field‐Effect transistor technology. While the Axon‐Hillock design achieves gigahertz throughput, its functional fragility persists. The Morris–Lecar model captures
Logan Larsh   +3 more
wiley   +1 more source

Mixed Mimetic Spectral Element method applied to Darcy's problem

open access: yes, 2013
We present a discretization for Darcy's problem using the recently developed Mimetic Spectral Element Method. The gist lies in the exact discrete representation of integral relations.
Gerritsma, Marc   +2 more
core   +1 more source

Mimetic Finite Difference Method for Shape Optimization Problems

open access: yes, 2014
We test the performance of the Mimetic Finite Difference method applied to a wide class of shape optimization problems. Adaptive strategies based on heuristic error indicators are also considered to validate the effectiveness of the numerical scheme.
ANTONIETTI, PAOLA FRANCESCA   +2 more
openaire   +2 more sources

Mimetic finite difference approximation of quasilinear elliptic problems

open access: yesCalcolo, 2014
The authors consider the following quasilinear elliptic problem \[ -\mathrm{div} (\kappa (|\nabla u|^2)\nabla u)=f \quad \text{in}\, \Omega, \qquad u=0\quad \text{on}\, \partial \Omega , \tag{1} \] where \(f\) is a given function and \(\Omega\) is an open, bounded set of \(\mathbb{R}^2\) with boundary \(\partial \Omega\).
ANTONIETTI, PAOLA FRANCESCA   +2 more
openaire   +3 more sources

A Stable Mimetic Finite-Difference Method for Convection-Dominated Diffusion Equations

open access: yesSIAM Journal on Scientific Computing, 2023
Convection-diffusion equations arise in a variety of applications such as particle transport, electromagnetics, and magnetohydrodynamics. Simulation of the convection-dominated regime for these problems, even with high-fidelity techniques, is particularly challenging due to the presence of sharp boundary layers and shocks causing jumps and ...
James H. Adler   +4 more
openaire   +2 more sources

Patterns of interspecific variation in labial microarchitecture among anthropoid primates and the evolution of the hominin lips

open access: yesThe Anatomical Record, EarlyView.
Comparative histological and semi‐automated image analysis of primate lips: Masson's trichrome‐stained sagittal sections were segmented to quantify the connective tissue, adipose, and muscular components, enabling interspecific comparisons of labial architecture.
Liat Rotenstreich   +5 more
wiley   +1 more source

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