Results 31 to 40 of about 13,734 (157)
Staggered grids discretization in three-dimensional Darcy convection
, 2008 We consider three-dimensional convection of an incompressible fluid saturated in a parallelepiped with a porous medium. A mimetic finite-difference scheme for the Darcy convection problem in the primitive variables is developed.
A.D. Nemtsev +22 more
core +1 more source
Vorinostat Potentiates Chemoimmunotherapy in Immune‐Enriched Pancreatic Cancer
Advanced Science, EarlyView.Immune‐enriched pancreatic cancer does not confer a significant survival advantage. SAHA sensitizes these “hot” tumors to chemoimmunotherapy by disrupting a FASN/PARP9‐driven “metabolic trap” and enhancing CD8+ T cell function. A CD8high/FASNhigh/PARP9high signature identifies patients who are most likely to benefit from the “gemcitabine‐nivolumab‐SAHA”
Chen Chen +13 more
wiley +1 more source
Compatible finite element methods for numerical weather prediction [PDF]
, 2014 This article takes the form of a tutorial on the use of a particular class of mixed finite element methods, which can be thought of as the finite element extension of the C-grid staggered finite difference method.
Cotter, C. J., McRae, A. T. T.
core
Mixed Mimetic Spectral Element method applied to Darcy's problem
, 2013 We present a discretization for Darcy's problem using the recently developed Mimetic Spectral Element Method. The gist lies in the exact discrete representation of integral relations.
Gerritsma, Marc +2 more
core +1 more source
Advanced Science, EarlyView.In this work, a bioinspired all‐in‐one underwater quality evaluation metamaterial, combining sound attenuation, diffuse reflection, and mechanical robustness, is proposed based on jumping spider locomotion and human skeletal biomechanics. Meanwhile, a CNN‑driven quality evaluation framework is established for theoretically dimension‐reduced ...
Hongze Li +8 more
wiley +1 more source
The nonconforming virtual element method for eigenvalue problems
, 2018 We analyse the nonconforming Virtual Element Method (VEM) for the approximation of elliptic eigenvalue problems. The nonconforming VEM allow to treat in the same formulation the two- and three-dimensional case.We present two possible formulations of the ...
Gardini, Francesca +2 more
core +1 more source
Advanced Science, EarlyView.We developed a RhPd‐H nanozyme that integrates enhanced POD‐mimetic catalytic activity with thermally triggered H2 release. H2 shields and reprograms mitochondria to continuously leak endogenous ·O2−. This dual‐path ROS spatially and temporally disrupts redox homeostasis, inducing persistent oxidative stress for tumor suppression and antitumor immunity,
Mingfan Shi +12 more
wiley +1 more source
Mimetic Finite Difference Method for Shape Optimization Problems
, 2014 We test the performance of the Mimetic Finite Difference method applied to a wide class of shape optimization problems. Adaptive strategies based on heuristic error indicators are also considered to validate the effectiveness of the numerical scheme.
ANTONIETTI, PAOLA FRANCESCA +2 more
openaire +2 more sources
A Hybrid High-Order method for Leray-Lions elliptic equations on general meshes
, 2016 In this work, we develop and analyze a Hybrid High-Order (HHO) method for steady non-linear Leray-Lions problems. The proposed method has several assets, including the support for arbitrary approximation orders and general polytopal meshes.
Di Pietro, Daniele A., Droniou, Jérôme
core +4 more sources
Temporal Interference Stimulation Enhances Neural Regeneration
Advanced Science, EarlyView.Temporal interference (TI) stimulation is proposed as a non‐invasive approach to enhance neural regeneration in the deep brain. Theta‐band TI modulation selectively promotes neural progenitor cell differentiation in vitro and augments hippocampal neurogenesis in amouse model of Alzheimer's disease‐like amyloidosis.
Sofia Peressott +15 more
wiley +1 more source