Results 251 to 260 of about 125,939 (330)

A Biomimetic Nanoparticle System Intercepts and Degrades Thrombospondin‐1 to Restore Vascular Homeostasis After Ischemic Injury

Advanced Science, EarlyView.
TAX2‐NPs capture extracellular TSP‐1 in the injured liver and promote its macrophage‐mediated autophagic degradation. This process blocks TSP‐1/CD47 signaling, restores VEGFR2‐AKT activity, preserves endothelial function, and mitigates hepatic ischemia‐reperfusion injury.
Haorui Wang, Xiandi Meng, Yanbao Xin, Kuirong Mao, Huizhu Tan, Changkai Ma, Xiuxiu Cong, Mengfei Zhao, Meiling Yu, Si Chen, Yue Hou, Yong‐Guang Yang, Tianmeng Sun   +12 more
wiley   +1 more source

Peptide-Incorporated Biomaterials Promote Regeneration of Peripheral Nerve Injuries. [PDF]

Adv Sci (Weinh)
Zhao Z, Liu J, Li J, Li D, Ding J, Liu B.   +5 more
europepmc   +1 more source

Convergency analysis of the high-order mimetic finite difference method

Konstantin Lipnikov, L Veiga Da Beirao, Gianmarco Manzini   +2 more
openalex   +1 more source

Pharmacokinetic Analysis of Insulin-mimetic Vanadyl Complexes in Rats. Metallokinetic Analysis by BCM-ESR Method and Neutron Activation Analysis.

, 2000
Hiroyuki Yasui, Hiromu Sakurai
openalex   +2 more sources

Self‐Accelerating Bimetallic Peroxide Nanozymes for Cascade‐Amplified Pyroptosis‐Immunotherapy

Advanced Science, EarlyView.
Acidic tumor microenvironment‐responsive CuZnONPs enable triple‐combination therapy via self‐supplying H2O2, cascade nanozyme activities for ROS burst, and Zn2+‐activated pyroptosis, synergizing catalytic therapy with immunotherapy to convert cold tumors into hot ones.
Xuanyi Lu, Liang Li, Siyu Pan, Yuehan Jian, Yuhan Chen, Wenjie Yang, Guang Song, Xueyang Fang, Ping'an Ma, Lijun Jiang   +9 more
wiley   +1 more source

Structure-Based Drug Discovery of Non-SAM-Mimetic Bisubstrate Inhibitors against Nicotinamide <i>N</i>‑Methyltransferase. [PDF]

ACS Med Chem Lett
Yoshida S, Kondo N, Uehara S, Yoshimura N, Sako Y, Yamamoto S, Kitade M, Tachibana Y.   +7 more
europepmc   +1 more source

A Cationic Supramolecule With Potent Antifungal Activity, Single‐Species Selectivity, and Strong Synergy With Echinocandins

Advanced Science, EarlyView.
We introduce a new membrane‐active antifungal design, Gua‐SMACS‐16, that exhibits high potency and single‐species selectivity for C. tropicalis while sparing other close species in the Candida genus. Moreover, when combining with caspofungin, a clinical antifungal drug inhibiting 1,3‐β‐glucan synthase, they exhibit ultra‐strong synergy across a panel ...
Tianjiao Dai, Adrielle Xianwen Chen, Eve Wai Ling Chow, Li Mei Pang, Jianguo Li, Chandra Shekhar Verma, Stefan H. Oehlers, Yue Wang, Ning Li   +8 more
wiley   +1 more source

Very-large-scale mimetic optogenetic synapses for physical reservoir computing. [PDF]

Nat Commun
Han X, Qi Z, Kundrat V, Li H, Li Z, Guo X, Mao P, Zheng W, Hou S, Liu R, Wu H, Wang P, Zak A, Liu W, Tenne R, Guo Y.   +15 more
europepmc   +1 more source

Quantum Dots for Biomedical Biosensing, NIR‐II Bioimaging, and Phototherapy: Materials Design, Signal Transduction, and Translational Barriers

Advanced Science, EarlyView.
This review outlines bottom‐up and biomimetic fabrication strategies of quantum dots, and highlights their emerging applications in biosensing, multimodal bioimaging, and intelligent cancer theranostics. It further discusses key translational barriers and future perspectives for advancing QD‐based nanomedicine toward clinical implementation.
Jie Ju, Zhifang Liu, Xinran Gao, Wen Sun, Wei Fu, Yanfei Wang   +5 more
wiley   +1 more source

Mutualisms within light microhabitats are associated with sensory convergence in a mimetic butterfly community. [PDF]

Proc Natl Acad Sci U S A
Wainwright JB, Loupasaki T, Ramírez F, Penry-Williams IL, England SJ, Barker A, Meier JI, How MJ, Roberts NW, Troscianko J, Montgomery SH.   +10 more
europepmc   +1 more source