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Journal of Virology, 2022
Virophages are a group of small double-stranded DNA viruses that infect protist hosts and parasitize the viral factory of host giant/large viruses to propagate. Here, we discover a novel cell-virus-virophage (CVv) tripartite interaction system by using unicellular micro-green algae (Chlorella sp.) as eukaryotic hosts for the first time. Viral particles,
Yongjie Wang
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Virophages are a group of small double-stranded DNA viruses that infect protist hosts and parasitize the viral factory of host giant/large viruses to propagate. Here, we discover a novel cell-virus-virophage (CVv) tripartite interaction system by using unicellular micro-green algae (Chlorella sp.) as eukaryotic hosts for the first time. Viral particles,
Yongjie Wang
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Journal of Virology, 2022
Parasitic virophages are small unicellular eukaryotic dsDNA viruses that rely on the viral factories of coinfecting giant/large dsDNA viruses for propagation. Presently, the identified eukaryotic hosts of isolated virophages were restricted to a free-living amoeba, Acanthamoeba polyphaga , and a widespread marine ...
Yijian Sheng +3 more
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Parasitic virophages are small unicellular eukaryotic dsDNA viruses that rely on the viral factories of coinfecting giant/large dsDNA viruses for propagation. Presently, the identified eukaryotic hosts of isolated virophages were restricted to a free-living amoeba, Acanthamoeba polyphaga , and a widespread marine ...
Yijian Sheng +3 more
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Megavirales Composing a Fourth Domain of Life: Mimiviridae and Marseilleviridae
2012The 2003 discovery of Acanthamoeba polyphaga Mimivirus led to several breakthroughs and subsequent discussions related to the evolution, origin and definition of viruses and dramatically boosted scientific interest in giant viruses. Mimivirus was the largest virus with respect to particle size and genome length, and its analysis blurred the paradigms ...
Philippe Colson, Didier Raoult
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Les virophages de Mimiviridae=The Mimiviridae virophages
Les virophages sont des petits virus à ADN possédant une capside icosaédrique de 50-60 nm et un génome de 17 à 26 Kb codant potentiellement pour une vingtaine de gènes. Ils ont été découverts associés à des grands virus à ADN appartenant à l’ordre des Megavirales, pour lesquels leur présence serait délétère.Le premier projet du travail de thèse a été ...openaire +1 more source
Mimivirus est le 1er virus géant découvert. Quelques années plus tard une nouvelle entité́ biologique a été décrite, les virophages. Si leurs principales caractéristiques sont maintenant bien définies et acceptées, leur position dans le monde viral ainsi que les interactions qu’ils pourraient avoir avec leur virus-hôte sont encore discutées. La famille
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Environmental microbiology, 2013
Giant viruses of the Megavirales order have been recently isolated from aquatic environments and have long been neglected because they are removed from samples during viral purification for viral metagenomic studies. Due to bacterial overgrowth and susceptibility to high concentrations of antibiotics, isolation by amoeba co-culture has a low efficiency
Mondher, Boughalmi +6 more
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Giant viruses of the Megavirales order have been recently isolated from aquatic environments and have long been neglected because they are removed from samples during viral purification for viral metagenomic studies. Due to bacterial overgrowth and susceptibility to high concentrations of antibiotics, isolation by amoeba co-culture has a low efficiency
Mondher, Boughalmi +6 more
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The SAMHD1 Virolog in Mimiviridae as a Defense against Virophages
Sterile α motif and HD domain-containing protein (SAMHD1) is the only deoxyribonucleosidetriphosphohydrolase in humans to break down dNTPs into the deoxy-bases and triphosphates toregulate dNTP molecular levels in a nucleotide- and metal-dependent mechanism.openaire +1 more source
A Functional K+ Channel from Tetraselmis Virus 1, a Member of the Mimiviridae
Viruses, 2020Andrea Cosimo Saponaro +2 more
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