Results 21 to 30 of about 1,437 (168)

The giant Cafeteria roenbergensis virus that infects a widespread marine phagocytic protist is a new member of the fourth domain of Life.

PLoS ONE, 2011
BackgroundA recent work has provided strong arguments in favor of a fourth domain of Life composed of nucleo-cytoplasmic large DNA viruses (NCLDVs). This hypothesis was supported by phylogenetic and phyletic analyses based on a common set of proteins ...
Philippe Colson, Gregory Gimenez, Mickaël Boyer, Ghislain Fournous, Didier Raoult   +4 more
doaj   +2 more sources

Extensive in silico analysis of Mimivirus coded Rab GTPase homolog suggests a possible role in virion membrane biogenesis

Frontiers in Microbiology, 2015
Rab GTPases are the key regulators of intracellular membrane trafficking in eukaryotes. Many viruses and intracellular bacterial pathogens have evolved to hijack the host Rab GTPase functions, mainly through activators and effector proteins, for their ...
Amrutraj eZade, Malavi eSengupta, Kiran eKondabagil   +2 more
doaj   +2 more sources

Infection by a Giant Virus (AaV) Induces Widespread Physiological Reprogramming in Aureococcus anophagefferens CCMP1984 – A Harmful Bloom Algae

Frontiers in Microbiology, 2018
While viruses with distinct phylogenetic origins and different nucleic acid types can infect and lyse eukaryotic phytoplankton, “giant” dsDNA viruses have been found to be associated with important ecological processes, including the collapse of algal ...
Mohammad Moniruzzaman, Mohammad Moniruzzaman, Eric R. Gann, Steven W. Wilhelm   +3 more
doaj   +2 more sources

Taxonomic update for giant viruses in the order Imitervirales (phylum Nucleocytoviricota). [PDF]

Arch Virol, 2023
Large DNA viruses in the phylum Nucleocytoviricota, sometimes referred to as “giant viruses” owing to their large genomes and virions, have been the subject of burgeoning interest over the last decade. Here, we describe recently adopted taxonomic updates
Aylward FO, Abrahão JS, Brussaard CPD, Fischer MG, Moniruzzaman M, Ogata H, Suttle CA.   +6 more
europepmc   +3 more sources

Presence of CRISPR CAS-Like Sequences as a Proposed Mechanism for Horizontal Genetic Exchanges between Trichomonas vaginalis and Its Associated Virus: A Comparative Genomic Analysis with the First Report of a Putative CRISPR CAS Structures in Eukaryotic Cells. [PDF]

Biomed Res Int, 2023
Introduction. Trichomonas vaginalis genome is among the largest genome size and coding capacities. Combinations of gene duplications, transposon, repeated sequences, and lateral gene transfers (LGTs) have contributed to the unexpected large genomic size and diversity. This study is aimed at investigating genomic exchange and seeking for presence of the
Kenarkoohi A, Abdoli A, Rostamzad A, Rashnavadi M, Naserifar R, Abdi J, Shams M, Bozorgomid A, Saeb S, Al-Fahad D, Khezri K, Falahi S.   +11 more
europepmc   +2 more sources

An efficient numerical representation of genome sequence: natural vector with covariance component [PDF]

PeerJ, 2022
Background The characterization and comparison of microbial sequences, including archaea, bacteria, viruses and fungi, are very important to understand their evolutionary origin and the population relationship.
Nan Sun, Xin Zhao, Stephen S.-T. Yau
doaj   +2 more sources

Comparative glycomic analysis of Mimiviridae and Marseilleviridae uncovers host-related and lineage-specific glycosylation. [PDF]

J Biochem
Abstract Giant viruses encode unusual glycosylation machinery distinct from their amoebal hosts, raising fundamental questions about how their glycans are synthesized and diversified. Here, we present a comparative glycomic analysis of mimivirus, tokyovirus and hokutovirus, together with their common host Acanthamoeba castellanii. The
Shim J, Hozumi C, Kurogochi M, Yagi-Utsumi M, Furukawa JI, Takemura M, Yagi H, Kato K.   +7 more
europepmc   +3 more sources

Gut Virome: What's the Role in Irritable Bowel Syndrome? [PDF]

Rev Med Virol
ABSTRACT The gut virome, an integral but still poorly understood component of the gut microbiota, is emerging as an important player in the pathophysiology of irritable bowel syndrome (IBS). Recent evidence suggests that alterations in virome diversity and phage–bacteria interactions contribute to gut dysbiosis, immune modulation and gut barrier ...
Rettura F, Lambiase C, Bottari A, Filippini F, Giacomelli L, Pistello M, Bellini M.   +6 more
europepmc   +2 more sources

Giant Viruses as a Source of Novel Enzymes for Biotechnological Application

Pathogens, 2022
The global demand for industrial enzymes has been increasing in recent years, and the search for new sources of these biological products is intense, especially in microorganisms.
Ellen Gonçalves de Oliveira, João Victor Rodrigues Pessoa Carvalho, Bruna Barbosa Botelho, Clécio Alonso da Costa Filho, Lethícia Ribeiro Henriques, Bruna Luiza de Azevedo, Rodrigo Araújo Lima Rodrigues   +6 more
doaj   +1 more source

Multiple infections of zoonotic pathogens in wild Brandt's voles (Lasiopodomys brandtii)

Veterinary Medicine and Science, Volume 9, Issue 5, Page 2201-2211, September 2023., 2023
Our research revealed the viral and bacterial diversity in wild Brandt's voles. The characterization and distinctive lineage of some rodent‐specific viruses (Cytomegalovirus, PestVs and Lentiviruses) and rodent‐borne bacteria (Leptospira interrogans and Vibrio cholerae) indicates that wild Brandt's voles may harbor a diversity of viruses and bacteria ...
Yongman Guo, Zhengrun Li, Shike Dong, Xiaoyan Si, Na Ta, Hanwei Liang, Lei Xu   +6 more
wiley   +1 more source