Results 51 to 60 of about 1,873 (181)
Frontiers in Microbiology, 2015 Rab GTPases are the key regulators of intracellular membrane trafficking in eukaryotes. Many viruses and intracellular bacterial pathogens have evolved to hijack the host Rab GTPase functions, mainly through activators and effector proteins, for their ...
Amrutraj eZade +2 more
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Extension of the viral ecology in humans using viral profile hidden Markov models. [PDF]
PLoS ONE, 2018 When human samples are sequenced, many assembled contigs are "unknown", as conventional alignments find no similarity to known sequences. Hidden Markov models (HMM) exploit the positions of specific nucleotides in protein-encoding codons in various ...
Zurab Bzhalava +2 more
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Oyster RNA-seq data support the development of Malacoherpesviridae genomics [PDF]
, 2017 The family of double-stranded DNA (dsDNA) Malacoherpesviridae includes viruses able to infect marine mollusks and detrimental for worldwide aquaculture production. Due to fast-occurring mortality and a lack of permissive cell lines, the available data on
Rosani, Umberto, Venier, Paola
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A new census of protein tandem repeats and their relationship with intrinsic disorder [PDF]
, 2020 Protein tandem repeats (TRs) are often associated with immunity-related functions and diseases. Since that last census of protein TRs in 1999, the number of curated proteins increased more than seven-fold and new TR prediction methods were published. TRs
Anisimova, Maria +4 more
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eLife, 2022 Mimivirus is the prototype of the Mimiviridae family of giant dsDNA viruses. Little is known about the organization of the 1.2 Mb genome inside the membrane-limited nucleoid filling the ~0.5 µm icosahedral capsids. Cryo-electron microscopy, cryo-electron
Alejandro Villalta +13 more
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Identification of Capsid/Coat Related Protein Folds and Their Utility for Virus Classification [PDF]
, 2017 The viral supergroup includes the entire collection of known and unknown viruses that roam our planet and infect life forms. The supergroup is remarkably diverse both in its genetics and morphology and has historically remained difficult to study and ...
Arshan Nasir, Gustavo Caetano-Anollés
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Mimiviridae: A Rising Family of Highly Diverse Large Aquatic dsDNA Viruses Infecting a Wide Variety of Eukaryotes [PDF]
, 2018 Since 1998, when Jim van Etten’s team initiated its characterization, Paramecium bursaria Chlorella virus 1 (PBCV-1) had been the largest known DNA virus, both in terms particle size and genome complexity. In 2003, The Acanthamoeba-infecting Mimivirus unexpectedly superseded PBCV-1, opening the era of giant viruses, i.e.
Jean-Michel Claverie, Chantal Abergel
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Frontiers in Microbiology, 2018 While viruses with distinct phylogenetic origins and different nucleic acid types can infect and lyse eukaryotic phytoplankton, “giant” dsDNA viruses have been found to be associated with important ecological processes, including the collapse of algal ...
Mohammad Moniruzzaman +3 more
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The analysis of translation-related gene set boosts debates around origin and evolution of mimiviruses. [PDF]
PLoS Genetics, 2017 The giant mimiviruses challenged the well-established concept of viruses, blurring the roots of the tree of life, mainly due to their genetic content.
Jônatas Santos Abrahão +3 more
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Morphological and Genomic Features of the New Klosneuvirinae Isolate Fadolivirus IHUMI-VV54
Frontiers in Microbiology, 2021 Since the discovery of Mimivirus, viruses with large genomes encoding components of the translation machinery and other cellular processes have been described as belonging to the nucleocytoplasmic large DNA viruses. Recently, genome-resolved metagenomics
Julien Andreani +5 more
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