Results 61 to 70 of about 2,142 (185)

Evolutionary Dynamics of Giant Viruses and their Virophages [PDF]

, 2013
Giant viruses contain large genomes, encode many proteins atypical for viruses, replicate in large viral factories, and tend to infect protists. The giant virus replication factories can in turn be infected by so called virophages, which are smaller ...
Anderson, Beddington, Briggs, Claverie, Claverie, Claverie, Claverie, Colson, Culley, Desnues, Desnues, Desnues, Fischer, Fischer, Forterre, Gillespie, Herrero-Uribe, Hochberg, Holt, Iyer, Koonin, Krupovic, Lawrence, May, McCallum, Nowak, Pearson, Raoult, Raoult, Roy, Ruiz-Saenz, Scola, Scola, Scola, Sun, Suzan-Monti, Wodarz, Yamada, Yau, Zhang   +39 more
core   +2 more sources

A new census of protein tandem repeats and their relationship with intrinsic disorder [PDF]

, 2020
Protein tandem repeats (TRs) are often associated with immunity-related functions and diseases. Since that last census of protein TRs in 1999, the number of curated proteins increased more than seven-fold and new TR prediction methods were published. TRs
Anisimova, Maria, Delucchi, Matteo, Elofsson, Arne, Sachenkova, Oxana, Schaper, Elke   +4 more
core   +1 more source

The giant Cafeteria roenbergensis virus that infects a widespread marine phagocytic protist is a new member of the fourth domain of Life.

PLoS ONE, 2011
BackgroundA recent work has provided strong arguments in favor of a fourth domain of Life composed of nucleo-cytoplasmic large DNA viruses (NCLDVs). This hypothesis was supported by phylogenetic and phyletic analyses based on a common set of proteins ...
Philippe Colson, Gregory Gimenez, Mickaël Boyer, Ghislain Fournous, Didier Raoult   +4 more
doaj   +1 more source

Exploring nucleo-cytoplasmic large DNA viruses in Tara Oceans microbial metagenomes [PDF]

, 2013
Nucleo-cytoplasmic large DNA viruses (NCLDVs) constitute a group of eukaryotic viruses that can have crucial ecological roles in the sea by accelerating the turnover of their unicellular hosts or by causing diseases in animals. To better characterize the
Acinas, Silvia G., Bork, Peer, Claverie, Jean-Michel, Clerissi, Camille, de Vargas, Colomban, Department of Applied Biological Sciences (DBIT), Vrije Universiteit Brussel, Brussels, Belgium, Department of Applied Biological Sciences (DBIT), Vrije Universiteit Brussel, Brussels, Belgium, Department of Applied Biological Sciences (DBIT), Vrije Universiteit Brussel, Brussels, Belgium, Desdevises, Yves, Faust, Karoline, Ferrera, Isabel, Grimsley, Nigel, Hingamp, Pascal, Jaillon, Olivier, Kandels-Lewis, Stefanie, Karsenti, Eric, Lima-Medez, Gipsi, Moreau, Hervé, Not, Fabrice, Ogata, Hiroyuki, Pesant, Stéphane, Poulain, Julie, Raes, Jeroen, Sarmento, Hugo, Subirana, Lucie, Sunagawa, Shinichi, Villar, Emilie, Wincker, Patrick   +27 more
core   +1 more source

Extensive in silico analysis of Mimivirus coded Rab GTPase homolog suggests a possible role in virion membrane biogenesis

Frontiers in Microbiology, 2015
Rab GTPases are the key regulators of intracellular membrane trafficking in eukaryotes. Many viruses and intracellular bacterial pathogens have evolved to hijack the host Rab GTPase functions, mainly through activators and effector proteins, for their ...
Amrutraj eZade, Malavi eSengupta, Kiran eKondabagil   +2 more
doaj   +1 more source

Extension of the viral ecology in humans using viral profile hidden Markov models. [PDF]

PLoS ONE, 2018
When human samples are sequenced, many assembled contigs are "unknown", as conventional alignments find no similarity to known sequences. Hidden Markov models (HMM) exploit the positions of specific nucleotides in protein-encoding codons in various ...
Zurab Bzhalava, Emilie Hultin, Joakim Dillner   +2 more
doaj   +1 more source

Lateral gene exchanges shape the genomes of amoeba-resisting microorganisms. [PDF]

, 2012
Based on Darwin's concept of the tree of life, vertical inheritance was thought to be dominant, and mutations, deletions, and duplication were streaming the genomes of living organisms.
Bertelli, C., Greub, G.
core   +2 more sources

The giant mimivirus 1.2 Mb genome is elegantly organized into a 30-nm diameter helical protein shield

eLife, 2022
Mimivirus is the prototype of the Mimiviridae family of giant dsDNA viruses. Little is known about the organization of the 1.2 Mb genome inside the membrane-limited nucleoid filling the ~0.5 µm icosahedral capsids. Cryo-electron microscopy, cryo-electron
Alejandro Villalta, Alain Schmitt, Leandro F Estrozi, Emmanuelle RJ Quemin, Jean-Marie Alempic, Audrey Lartigue, Vojtěch Pražák, Lucid Belmudes, Daven Vasishtan, Agathe MG Colmant, Flora A Honoré, Yohann Couté, Kay Grünewald, Chantal Abergel   +13 more
doaj   +1 more source

Identification of Capsid/Coat Related Protein Folds and Their Utility for Virus Classification [PDF]

, 2017
The viral supergroup includes the entire collection of known and unknown viruses that roam our planet and infect life forms. The supergroup is remarkably diverse both in its genetics and morphology and has historically remained difficult to study and ...
Arshan Nasir, Gustavo Caetano-Anollés
core   +1 more source

Infection by a Giant Virus (AaV) Induces Widespread Physiological Reprogramming in Aureococcus anophagefferens CCMP1984 – A Harmful Bloom Algae

Frontiers in Microbiology, 2018
While viruses with distinct phylogenetic origins and different nucleic acid types can infect and lyse eukaryotic phytoplankton, “giant” dsDNA viruses have been found to be associated with important ecological processes, including the collapse of algal ...
Mohammad Moniruzzaman, Mohammad Moniruzzaman, Eric R. Gann, Steven W. Wilhelm   +3 more
doaj   +1 more source