Results 1 to 10 of about 4,180 (166)

Acanthamoeba polyphaga de novo transcriptome and its dynamics during Mimivirus infection [PDF]

Scientific Reports, 2022
Mimivirus bradfordmassiliense (Mimivirus) is a giant virus that infects Acanthamoeba species – opportunistic human pathogens. Long- and short-read sequencing were used to generate a de novo transcriptome of the host and followed the dynamics of both host
Reut Bickels Nuri, Ester Feldmesser, Yael Fridmann-Sirkis, Hadas Keren-Shaul, Reinat Nevo, Abraham Minsky, Ziv Reich   +6 more
doaj   +3 more sources

Amoebal Tubulin Cleavage Late during Infection Is a Characteristic Feature of Mimivirus but Not of Marseillevirus [PDF]

Microbiology Spectrum, 2022
Mimivirus and Marseillevirus infections of Acanthamoeba castellanii, like most other viral infections, induce cytopathic effects (CPE). The details of how they bring about CPE and to what extent and how they modify the host cytoskeletal network are ...
Nisha Goyal, Amlan Barai, Shamik Sen, Kiran Kondabagil   +3 more
doaj   +3 more sources

Visualization of giant Mimivirus in a movie for biology classrooms [PDF]

Journal of Microbiology & Biology Education
We have developed a new observation chamber for Mimivirus-infected Acanthamoeba to create dynamic visual teaching materials for virus education suitable for high school and university biology courses.
Kanako Morioka, Ayumi Fujieda, Masaharu Takemura   +2 more
doaj   +3 more sources

Mimivirus transcription and translation occur at well-defined locations within amoeba host cells [PDF]

Journal of Virology
Many giant viruses replicate in the cytoplasm in viral factories. How exactly these viral factories are established and where the different steps of the replication cycle occur remain largely obscure.
Lotte Mayer, Georgi Nikolov, Martin Kunert, Matthias Horn, Anouk Willemsen   +4 more
doaj   +3 more sources

Detection of Mimivirus from respiratory samples in tuberculosis-suspected patients

Scientific Reports, 2022
Acanthamoeba polyphaga mimivirus (APMV), a species of amoeba-infecting giant viruses, has recently emerged as human respiratory pathogens. This study aimed to evaluate the presence of Mimivirus in respiratory samples, collected from tuberculosis (TB ...
Fatemeh Sakhaee, Jalal Mosayebi Amroabadi, Sara Razi, Farzam Vaziri, Farid Abdolrahimi, Sina Moghaddam, Fatemeh Rahimi Jamnani, Seyed Davar Siadat, Abolfazl Fateh   +8 more
doaj   +2 more sources

The Discovery of a New Mimivirus Isolate in Association with Virophage-Transpoviron Elements in Brazil Highlights the Main Genomic and Evolutionary Features of This Tripartite System

Viruses, 2022
Mimiviruses are giant viruses of amoeba that can be found in association with virophages. These satellite-like viruses are dependent on the mimivirus viral factory to replicate.
Bruna Luiza de Azevedo, João Pessoa Araújo Júnior, Leila Sabrina Ullmann, Rodrigo Araújo Lima Rodrigues, Jônatas Santos Abrahão   +4 more
doaj   +2 more sources

Mimivirus relatives in the Sargasso sea [PDF]

Virology Journal, 2005
The discovery and genome analysis of Acanthamoeba polyphaga Mimivirus, the largest known DNA virus, challenged much of the accepted dogma regarding viruses. Its particle size (>400 nm), genome length (1.2 million bp) and huge gene repertoire (911 protein
Claverie Jean-Michel, Ghedin Elodie
doaj   +7 more sources

The giant mimivirus 1.2 Mb genome is elegantly organized into a 30-nm diameter helical protein shield

eLife, 2022
Mimivirus is the prototype of the Mimiviridae family of giant dsDNA viruses. Little is known about the organization of the 1.2 Mb genome inside the membrane-limited nucleoid filling the ~0.5 µm icosahedral capsids. Cryo-electron microscopy, cryo-electron
Alejandro Villalta, Alain Schmitt, Leandro F Estrozi, Emmanuelle RJ Quemin, Jean-Marie Alempic, Audrey Lartigue, Vojtěch Pražák, Lucid Belmudes, Daven Vasishtan, Agathe MG Colmant, Flora A Honoré, Yohann Couté, Kay Grünewald, Chantal Abergel   +13 more
doaj   +2 more sources

Diversity of Surface Fibril Patterns in Mimivirus Isolates. [PDF]

J Virol, 2023
Mimivirus fibrils are intriguing structures that have drawn attention since their discovery. Although still under investigation, the function of fibrils may be related to host cell adhesion.
de Aquino ILM, Serafim MSM, Machado TB, Azevedo BL, Cunha DES, Ullmann LS, Araújo JP, Abrahão JS.   +7 more
europepmc   +2 more sources

Functional redundancy revealed by the deletion of the mimivirus GMC-oxidoreductase genes. [PDF]

Microlife
The mimivirus 1.2Mb genome was shown to be organized into a nucleocapsid-like genomic fiber encased in the nucleoid compartment inside the icosahedral capsid (1). The genomic fiber protein shell is composed of a mixture of two GMC-oxidoreductase paralogs,
Alempic JM, Bisio H, Villalta A, Santini S, Lartigue A, Schmitt A, Bugnot C, Notaro A, Belmudes L, Adrait A, Poirot O, Ptchelkine D, De Castro C, Couté Y, Abergel C.   +14 more
europepmc   +2 more sources