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Mimivirus in Pneumonia Patients
Mimivirus, the largest virus known to date, is an amebal pathogen like Legionella spp. When mimivirus was used as an antigen in a migration inhibition factor assay, seroconversion was found in patients with both community- and hospital-acquired pneumonia.
Bernard La Scola +3 more
doaj +3 more sources
Structural studies of the giant mimivirus.
Mimivirus is the largest known virus whose genome and physical size are comparable to some small bacteria, blurring the boundary between a virus and a cell.
Chuan Xiao +9 more
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Mimivirus relatives in the Sargasso sea [PDF]
The discovery and genome analysis of Acanthamoeba polyphaga Mimivirus, the largest known DNA virus, challenged much of the accepted dogma regarding viruses. Its particle size (>400 nm), genome length (1.2 million bp) and huge gene repertoire (911 protein
Claverie Jean-Michel, Ghedin Elodie
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PCR Detection of Mimivirus [PDF]
In an epidemiological study, mimivirus was reported as an unlikely cause of human respiratory infections in China. Our analysis revealed the nonsensitivity of the PCR method, which detected less than 10% of the current known mimivirus.
Didier Raoult +2 more
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A new example of viral intein in Mimivirus [PDF]
Background Inteins are "protein introns" that remove themselves from their host proteins through an autocatalytic protein-splicing. After their discovery, inteins have been quickly identified in all domains of life, but only once to date in the genome of
Claverie Jean-Michel +2 more
doaj +3 more sources
Marine mimivirus relatives are probably large algal viruses [PDF]
Background Acanthamoeba polyphaga mimivirus is the largest known ds-DNA virus and its 1.2 Mb-genome sequence has revealed many unique features. Mimivirus occupies an independent lineage among eukaryotic viruses and its known hosts include only species ...
Claverie Jean-Michel +5 more
doaj +5 more sources
Structural and functional insights into Mimivirus ORFans [PDF]
Background Mimivirus isolated from A. polyphaga is the largest virus discovered so far. It is unique among all the viruses in having genes related to translation, DNA repair and replication which bear close homology to eukaryotic genes.
Fischer Daniel, Saini Harpreet
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Screening Pneumonia Patients for Mimivirus
Acanthamoeba polyphaga mimivirus (APM), a virus of free-living amebae, has reportedly caused human respiratory disease. Using 2 newly developed real-time PCR assays, we screened 496 respiratory specimens from 9 pneumonia-patient populations for APM. This
Ryan K. Dare +2 more
doaj +3 more sources
Membrane assembly during the infection cycle of the giant Mimivirus. [PDF]
Although extensively studied, the structure, cellular origin and assembly mechanism of internal membranes during viral infection remain unclear. By combining diverse imaging techniques, including the novel Scanning-Transmission Electron Microscopy ...
Yael Mutsafi +3 more
doaj +4 more sources

