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PCR Detection of Mimivirus [PDF]

open access: yesEmerging Infectious Diseases, 2017
In an epidemiological study, mimivirus was reported as an unlikely cause of human respiratory infections in China. Our analysis revealed the nonsensitivity of the PCR method, which detected less than 10% of the current known mimivirus.
Didier Raoult   +2 more
doaj   +3 more sources

Exposure to Mimivirus collagen promotes arthritis [PDF]

open access: yesJournal of Virology, 2014
Collagens, the most abundant proteins in animals, also occur in some recently described nucleocytoplasmic large DNA viruses such as Mimiviridae, which replicate in amoebae.
Gay, Steffen   +5 more
core   +4 more sources

Pulmonary Infection Related to Mimivirus in Patient with Primary Ciliary Dyskinesia

open access: yesEmerging Infectious Diseases, 2020
Primary ciliary dyskinesia is a rare autosomal recessive disorder that causes oto-sino-pulmonary disease. We report a case of pulmonary infection related to mimivirus in a 10-year-old boy with primary ciliary dyskinesia that was identified using ...
Fatemeh Sakhaee   +4 more
doaj   +2 more sources

The Mimivirus L375 Nudix enzyme hydrolyzes the 5' mRNA cap.

open access: yesPLoS ONE, 2021
The giant Mimivirus is a member of the nucleocytoplasmic large DNA viruses (NCLDV), a group of diverse viruses that contain double-stranded DNA (dsDNA) genomes that replicate primarily in eukaryotic hosts.
Grace Kago, Susan Parrish
doaj   +2 more sources

A new example of viral intein in Mimivirus [PDF]

open access: yesVirology Journal, 2005
Background Inteins are "protein introns" that remove themselves from their host proteins through an autocatalytic protein-splicing. After their discovery, inteins have been quickly identified in all domains of life, but only once to date in the genome of
Claverie Jean-Michel   +2 more
doaj   +3 more sources

Intracellular iron positively modulates the replicative cycle of mimiviruses, increasing virus production [PDF]

open access: yesJournal of Virology
Mimiviruses, members of the Nucleocytoviricota phylum, produce large, pseudo-icosahedral virions densely coated with fibrils, except at a specialized fivefold vertex known as the stargate.
Juliana dos Santos Oliveira   +9 more
doaj   +2 more sources

Marine mimivirus relatives are probably large algal viruses [PDF]

open access: yesVirology Journal, 2008
Background Acanthamoeba polyphaga mimivirus is the largest known ds-DNA virus and its 1.2 Mb-genome sequence has revealed many unique features. Mimivirus occupies an independent lineage among eukaryotic viruses and its known hosts include only species ...
Claverie Jean-Michel   +5 more
doaj   +5 more sources

Screening Pneumonia Patients for Mimivirus

open access: yesEmerging Infectious Diseases, 2008
Acanthamoeba polyphaga mimivirus (APM), a virus of free-living amebae, has reportedly caused human respiratory disease. Using 2 newly developed real-time PCR assays, we screened 496 respiratory specimens from 9 pneumonia-patient populations for APM. This
Ryan K. Dare   +2 more
doaj   +3 more sources

Structural and functional insights into Mimivirus ORFans [PDF]

open access: yesBMC Genomics, 2007
Background Mimivirus isolated from A. polyphaga is the largest virus discovered so far. It is unique among all the viruses in having genes related to translation, DNA repair and replication which bear close homology to eukaryotic genes.
Fischer Daniel, Saini Harpreet
doaj   +3 more sources

Gene & Genome Duplication in Acanthamoeba Polyphaga Mimivirus

open access: yes, 2005
accepted for publication in "Journal of Virology"Gene duplication is key to molecular evolution in all three domains of life and may be the first step in the emergence of new gene function.
Suhre, Karsten
core   +4 more sources

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