Results 21 to 30 of about 1,877 (147)

Presence of CRISPR CAS-Like Sequences as a Proposed Mechanism for Horizontal Genetic Exchanges between Trichomonas vaginalis and Its Associated Virus: A Comparative Genomic Analysis with the First Report of a Putative CRISPR CAS Structures in Eukaryotic Cells. [PDF]

Biomed Res Int, 2023
Introduction. Trichomonas vaginalis genome is among the largest genome size and coding capacities. Combinations of gene duplications, transposon, repeated sequences, and lateral gene transfers (LGTs) have contributed to the unexpected large genomic size and diversity. This study is aimed at investigating genomic exchange and seeking for presence of the
Kenarkoohi A, Abdoli A, Rostamzad A, Rashnavadi M, Naserifar R, Abdi J, Shams M, Bozorgomid A, Saeb S, Al-Fahad D, Khezri K, Falahi S.   +11 more
europepmc   +2 more sources

Water, Water Everywhere, but Every Drop Unique: Challenges in the Science to Understand the Role of Contaminants of Emerging Concern in the Management of Drinking Water Supplies

GeoHealth, Volume 7, Issue 12, December 2023., 2023
Abstract The protection and management of water resources continues to be challenged by multiple and ongoing factors such as shifts in demographic, social, economic, and public health requirements. Physical limitations placed on access to potable supplies include natural and human‐caused factors such as aquifer depletion, aging infrastructure ...
Susan T. Glassmeyer, Emily E. Burns, Michael J. Focazio, Edward T. Furlong, Matthew O. Gribble, Michael A. Jahne, Scott P. Keely, Alison R. Kennicutt, Dana W. Kolpin, Elizabeth K. Medlock Kakaley, Stacy L. Pfaller   +10 more
wiley   +1 more source

Expanding the Occurrence of Polysaccharides to the Viral World: The Case of Mimivirus

Angewandte Chemie, Volume 133, Issue 36, Page 20050-20057, September 1, 2021., 2021
The giant virus Mimivirus has an icosahedral capsid embedded in a thick layer of fibrils, resembling the glycocalyx of many bacteria. This study revealed that these fibrils are composed by a limited set of carrier proteins which bear two distinct polysaccharides.
Anna Notaro, Yohann Couté, Lucid Belmudes, Maria Elena Laugieri, Annalisa Salis, Gianluca Damonte, Antonio Molinaro, Michela G. Tonetti, Chantal Abergel, Cristina De Castro   +9 more
wiley   +2 more sources

From viral democratic genomes to viral wild bunch of quasispecies

Journal of Medical Virology, Volume 95, Issue 11, November 2023., 2023
Abstract The tremendous majority of RNA genomes from pathogenic viruses analyzed and deposited in databases are consensus or “democratic” genomes. They represent the genomes most frequently found in the clinical samples of patients but do not account for the huge genetic diversity of coexisting genomes, which is better described as quasispecies.
Philippe Colson, Wahiba Bader, Jacques Fantini, Pierre Dudouet, Anthony Levasseur, Pierre Pontarotti, Christian Devaux, Didier Raoult   +7 more
wiley   +1 more source

A rapid genome‐wide analysis of isolated giant viruses using MinION sequencing

Environmental Microbiology, Volume 25, Issue 11, Page 2621-2635, November 2023., 2023
We evaluated performance of MinION sequencing for giant virus genomics. Re‐sequencing of a prototype marseillevirus by MinION alone provided high‐quality genomes. As a proof of concept, we sequenced genomes of newly isolated giant viruses. Collectively, we concluded that MinION sequencing is an effective approach to rapidly perform a genome‐wide ...
Hiroyuki Hikida, Yusuke Okazaki, Ruixuan Zhang, Thi Tuyen Nguyen, Hiroyuki Ogata   +4 more
wiley   +1 more source

The return of the “Mistigri” (virus adaptative gain by gene loss) through the SARS‐CoV‐2 XBB.1.5 chimera that predominated in 2023

Journal of Medical Virology, Volume 95, Issue 10, October 2023., 2023
Abstract Severe acute respiratory syndrome coronavirus 2 XBB.1.5 is the first recombinant lineage to predominate at the country and global scales. Very interestingly, like the Marseille‐4B subvariant (or B.1.160) and the pandemic variant B.1.1.7 (or Alpha) previously, it has its ORF8 gene inactivated by a stop codon.
Philippe Colson, Jérémy Delerce, Jacques Fantini, Pierre Pontarotti, Bernard La Scola, Didier Raoult   +5 more
wiley   +1 more source

Revolving ATPase motors as asymmetrical hexamers in translocating lengthy dsDNA via conformational changes and electrostatic interactions in phi29, T7, herpesvirus, mimivirus, E. coli, and Streptomyces

Exploration, Volume 3, Issue 2, April 2023., 2023
The revolving DNA motors of ATPase have been found in viruses (phi29, T7, herpesvirus, and mimivirus) and bacteria (E. coli and Streptomyces). The motors made of asymmetrical 6 subunits translocate lengthy double‐stranded (ds)DNA. The dsDNA is moved in a circular motion around the inner surface of the motor channel subunits.
Tao Weitao, Giovanna Grandinetti, Peixuan Guo   +2 more
wiley   +1 more source

Pleistocene glacial and interglacial ecosystems inferred from ancient DNA analyses of permafrost sediments from Batagay megaslump, East Siberia

Environmental DNA, Volume 4, Issue 6, Page 1265-1283, November 2022., 2022
As the past is the key to the future, to understand community transformations and ecological interactions, we reconstructed ecosystem‐wide biotic composition (from viruses to megaherbivores) between glacials and interglacials from the Middle and Late Pleistocene at the Batagay megaslump, east Siberia.
Jérémy Courtin, Amedea Perfumo, Andrei A. Andreev, Thomas Opel, Kathleen R. Stoof‐Leichsenring, Mary E. Edwards, Julian B. Murton, Ulrike Herzschuh   +7 more
wiley   +1 more source

Bacteriophages pass through candle‐shaped porous ceramic filters: Application for the collection of viruses in soil water

MicrobiologyOpen, Volume 11, Issue 5, October 2022., 2022
This study proposes to use porous candles as a new tool for collecting soil water viruses. In the first step, the passage of model viruses through the ceramic part of the candles was investigated. Regarding the field application, the experiments carried out showed a successful recovery of viruses, demonstrating the relevance and efficiency of such a ...
Perrine Florent, Henry‐Michel Cauchie, Malte Herold, Leslie Ogorzaly   +3 more
wiley   +1 more source

Megaviruses contain various genes encoding for eukaryotic vesicle trafficking factors

Traffic, Volume 23, Issue 8, Page 414-425, August 2022., 2022
Giant viruses enter their eukaryotic host cells by phagocytosis. For reproduction, they hijack the host cell's membranes by an unknown mechanism. Here, we found that giant viruses express several core factors of the eukaryotic vesicle fusion machinery, including SNARE, Rab, SM proteins, and the disassembly protein NSF.
Dany Khalifeh, Emilie Neveu, Dirk Fasshauer   +2 more
wiley   +1 more source