Results 61 to 70 of about 1,877 (147)
Amoebae, Giant Viruses, and Virophages Make Up a Complex, Multilayered Threesome
Frontiers in Cellular and Infection Microbiology, 2018 Viral infection had not been observed for amoebae, until the Acanthamoeba polyphaga mimivirus (APMV) was discovered in 2003. APMV belongs to the nucleocytoplasmatic large DNA virus (NCLDV) family and infects not only A.
Jan Diesend +3 more
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Diversity and structural‐functional insights of alpha‐solenoid proteins
Protein Science, Volume 33, Issue 11, November 2024.Abstract Alpha‐solenoids are a significant and diverse subset of structured tandem repeat proteins (STRPs) that are important in various domains of life. This review examines their structural and functional diversity and highlights their role in critical cellular processes such as signaling, apoptosis, and transcriptional regulation.
Paula Nazarena Arrías +5 more
wiley +1 more source
Exploring ORFan domains in giant viruses: structure of mimivirus sulfhydryl oxidase R596.
PLoS ONE, 2012 The mimivirus genome contains many genes that lack homologs in the sequence database and are thus known as ORFans. In addition, mimivirus genes that encode proteins belonging to known fold families are in some cases fused to domain-sized segments that ...
Motti Hakim +4 more
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Acanthamoeba polyphaga mimivirus stability in environmental and clinical substrates: implications for virus detection and isolation. [PDF]
PLoS ONE, 2014 Viruses are extremely diverse and abundant and are present in countless environments. Giant viruses of the Megavirales order have emerged as a fascinating research topic for virologists around the world.
Fábio P Dornas +9 more
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From Mimivirus to Mirusvirus: The Quest for Hidden Giants
Viruses, 2023 Our perception of viruses has been drastically evolving since the inception of the field of virology over a century ago. In particular, the discovery of giant viruses from the Nucleocytoviricota phylum marked a pivotal moment. Their previously concealed diversity and abundance unearthed an unprecedented complexity in the virus world, a complexity that ...
Gaïa, Morgan, Forterre, Patrick
openaire +5 more sources
The Mimivirus L375 Nudix enzyme hydrolyzes the 5' mRNA cap.
PLoS ONE, 2021 The giant Mimivirus is a member of the nucleocytoplasmic large DNA viruses (NCLDV), a group of diverse viruses that contain double-stranded DNA (dsDNA) genomes that replicate primarily in eukaryotic hosts.
Grace Kago, Susan Parrish
doaj +1 more source
A Mimivirus Enzyme that Participates in Viral Entry [PDF]
Structure, 2015 Mimivirus was initially identified as a bacterium because its dense, 125-nm-long fibers stained Gram-positively. These fibers probably play a role during the infection of some host cells. The normal hosts of Mimivirus are unknown, but in the laboratory Mimivirus is usually propagated in amoeba.
Klose, Thomas +5 more
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Ameba-associated Microorganisms and Diagnosis of Nosocomial Pneumonia
Emerging Infectious Diseases, 2006 To elucidate the role of ameba-associated microorganisms (AAMs) as etiologic agents of pneumonia, we screened for Legionella spp., Parachlamydia acanthamoeba, Afipia sp., Bosea spp., Bradyrhizobium spp., Mesorhizobium amorphae, Rasbo bacterium ...
Pierre Berger +5 more
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Diversity of Amoeba-Associated Giant Viruses Isolated in Algeria
Diversity, 2020 The discovery of several giant amoeba viruses has opened up a novel area in the field of virology. Despite this, knowledge about ecology of these viruses remains patchy. In this study, we aimed to characterize the diversity of giant viruses in Algeria by
Hadjer Boudjemaa +3 more
doaj +1 more source
Crystal structure of mimivirus uracil-DNA glycosylase
PLOS ONE, 2017 Cytosine deamination induced by stresses or enzymatic catalysis converts deoxycytidine into deoxyuridine, thereby introducing a G to A mutation after DNA replication. Base-excision repair to correct uracil to cytosine is initiated by uracil-DNA glycosylase (UDG), which recognizes and eliminates uracil from DNA.
Eunju Kwon +3 more
openaire +4 more sources