Mimivirus and the emerging concept of “giant” virus [PDF]
Virus Research, 2006 Submitted to Virus ...
Claverie, Jean-Michel +5 more
openaire +3 more sources
Genome Characterization of the First Mimiviruses of Lineage C Isolated in Brazil
Frontiers in Microbiology, 2017 The family Mimiviridae, comprised by giant DNA viruses, has been increasingly studied since the isolation of the Acanthamoeba polyphaga mimivirus (APMV), in 2003.
Felipe L. Assis +9 more
doaj +1 more source
Role of the R349 Gene and Its Repeats in the MIMIVIRE Defense System
Frontiers in Microbiology, 2019 MIMIVIRE is a defense system described in lineage A Mimivirus (Mimiviridae family) that mediates resistance against Zamilon virophage. It is composed of putative helicase and nuclease associated with a gene of unknown function called R349, which contains
Said Mougari +5 more
doaj +1 more source
Broad spectrum of mimiviridae virophage allows its isolation using a mimivirus reporter. [PDF]
PLoS ONE, 2013 The giant virus Mimiviridae family includes 3 groups of viruses: group A (includes Acanthamoeba polyphaga Mimivirus), group B (includes Moumouvirus) and group C (includes Megavirus chilensis).
Morgan Gaia +5 more
doaj +1 more source
Genome signatures, self-organizing maps and higher order phylogenies: a parametric analysis [PDF]
, 2007 Genome signatures are data vectors derived from the compositional statistics of DNA. The self-organizing map (SOM) is a neural network method for the conceptualisation of relationships within complex data, such as genome signatures.
Gatherer, Derek
core +4 more sources
Mimivirus shows dramatic genome reduction after intraamoebal culture [PDF]
Proceedings of the National Academy of Sciences, 2011 Most phagocytic protist viruses have large particles and genomes as well as many laterally acquired genes that may be associated with a sympatric intracellular life (a community-associated lifestyle with viruses, bacteria, and eukaryotes) and the presence of virophages.
Boyer, Mickaël +14 more
openaire +3 more sources
Generation of a recombinant mimivirus by direct transfection of a PCR amplicon
bioRxivGiant viruses are large double-stranded DNA viruses encoding hundreds of genes. These genes are considered to reprogram the host cell machinery, which, in turn, modulates the global nutrient cycles in the environment.
Hiroyuki Hikida, Hiroyuki Ogata
semanticscholar +1 more source
The Mimivirus 1.2 Mb dsDNA genome is elegantly organized into a nuclear-like weapon
, 2021 Mimivirus is the prototype of the Mimiviridae family of giant dsDNA viruses, initially isolated in Acanthamoeba1. Little is known about the organization of the viral genome inside the membrane limited nucleoid2 and whether unpacking or other ...
C. Abergel +12 more
semanticscholar +1 more source
Characterization of mimivirus NAD+-dependent DNA ligase
Virology, 2006 Mimivirus, a parasite of Acanthamoeba polyphaga, is the largest DNA virus known; it encodes a cornucopia of proteins with imputed functions in DNA replication, modification, and repair. Here we produced, purified, and characterized mimivirus DNA ligase (MimiLIG), an NAD+-dependent nick joining enzyme homologous to bacterial LigA and entomopoxvirus DNA ...
Benarroch, Delphine, Shuman, Stewart
openaire +2 more sources
Identification of giant Mimivirus protein functions using RNA interference
Frontiers in Microbiology, 2015 Genomic analysis of giant viruses, such as Mimivirus, has revealed that more than half of the putative genes have no known functions (ORFans). We knocked down Mimivirus genes using short interfering RNA (siRNA) as a proof of concept to determine the ...
Haitham eSobhy +7 more
doaj +1 more source