Amoebal pathogens as emerging causal agents of pneumonia [PDF]
, 2017 Despite using modern microbiological diagnostic approaches, the aetiological agents of pneumonia remain unidentified in about 50% of cases. Some bacteria that grow poorly or not at all in axenic media used in routine clinical bacteriology laboratory but ...
Greub, Gilbert, Lamoth, Frédéric
core
Non-destructive imaging of an individual protein [PDF]
, 2012 The mode of action of proteins is to a large extent given by their ability to adopt different conformations. This is why imaging single biomolecules at atomic resolution is one of the ultimate goals of biophysics and structural biology.
C. Escher +4 more
core +1 more source
Viruses, 2019 Viruses are the most prevalent infectious agents, populating almost every ecosystem on earth. Most viruses carry only a handful of genes supporting their replication and the production of capsids.
Nadav Brandes, Michal Linial
doaj +1 more source
Screening Pneumonia Patients for Mimivirus
Emerging Infectious Diseases, 2008 Acanthamoeba polyphaga mimivirus (APM), a virus of free-living amebae, has reportedly caused human respiratory disease. Using 2 newly developed real-time PCR assays, we screened 496 respiratory specimens from 9 pneumonia-patient populations for APM. This
Ryan K. Dare +2 more
doaj +1 more source
Three-dimensional double helical DNA structure directly revealed from its X-ray fiber diffraction pattern by iterative phase retrieval [PDF]
, 2018 Coherent diffraction imaging (CDI) allows the retrieval of the structure of an isolated object, such as a macromolecule, from its diffraction pattern. CDI requires the fulfilment of two conditions: the imaging radiation must be coherent and the object ...
Fink, Hans-Werner +1 more
core +1 more source
Stem-Loop RNA Hairpins in Giant Viruses: Invading rRNA-Like Repeats and a Template Free RNA
Frontiers in Microbiology, 2018 We examine the hypothesis that de novo template-free RNAs still form spontaneously, as they did at the origins of life, invade modern genomes, contribute new genetic material.
Hervé Seligmann, Didier Raoult
doaj +1 more source
Varieties of living things: Life at the intersection of lineage and metabolism [PDF]
, 2013 publication-status: Publishedtypes ...
A Bodył +193 more
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Holography and Coherent Diffraction with Low-Energy Electrons: A Route towards Structural Biology at the Single Molecule Level [PDF]
, 2015 The current state of the art in structural biology is led by NMR, X-ray crystallography and TEM investigations. These powerful tools however all rely on averaging over a large ensemble of molecules.
Escher, Conrad +3 more
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Single-Shot Electron Diffraction using a Cold Atom Electron Source [PDF]
, 2015 Cold atom electron sources are a promising alternative to traditional photocathode sources for use in ultrafast electron diffraction due to greatly reduced electron temperature at creation, and the potential for a corresponding increase in brightness ...
McCulloch, Andrew J. +5 more
core +2 more sources
Quantum Imaging with Incoherently Scattered Light from a Free-Electron Laser [PDF]
, 2017 The advent of accelerator-driven free-electron lasers (FEL) has opened new avenues for high-resolution structure determination via diffraction methods that go far beyond conventional x-ray crystallography methods.
A Aquila +49 more
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