Results 61 to 70 of about 450,539 (268)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Design of Explosion-proof and Intrinsic Safety DC Stabilized UPS Used in Coal Mine

Gong-kuang zidonghua, 2012
The paper put forward a design scheme of explosion-proof and intrinsic safety DC stabilized UPS used in coal mine based on the principle and characteristics of intrinsic safety power supply, introduced design of main circuit of the power supply.
ZHAO Si-hai, ZHOU Jie
doaj  

Energy consumption standards and costs in South African gold and platinum mines [PDF]

, 2009
Benchmarking of selected energy use indicators and related best practices definition are helpful tools in establishing an effective energy reduction and energy efficiency strategy.
Tshisekedi, Jean Rene Ngalamulume
core  

Platinum City and the New South African Dream [PDF]

, 2012
Much has been written about the persistence of economic apartheid inscribed on the geography of South Africa’s cities. This has intensified fragmentation, producing spatial configurations that are at once reminiscent of the old order of segregation, and
Barnes, Blim, Bozzoli, Carstens, Cooper, Cruikshank, Dinah Rajak, Dolan, Ferguson, Fumanti, Khumalo, Parnell, Southall, Zwennis   +13 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Novel cable measurement while drilling device used for directional drilling in coal mine

Gong-kuang zidonghua, 2015
In order to solve problems of short usage time, poor signal stability, high fault ratio and high maintenance cost of existing cable measurement while drilling device for coal mine drilling which was powered by battery in hole, a technology scheme was ...
FANG Jun, SHI Zhijun, LI Quanxin, GAO Jun   +3 more
doaj   +1 more source

Financial Risks of Investments in Coal [PDF]

, 2011
Analyzes the regulatory, commodity, and construction risks of investing in coal mining and coal-fired power plants. Examines industry analysts' consensus on viable alternatives to coal, including natural gas, solar, wind, and energy ...
Amy Galland, Leslie Lowe, Tom Sanzillo
core  

Eureka and beyond: mining's impact on African urbanisation [PDF]

, 2012
This collection brings separate literatures on mining and urbanisation together at a time when both artisanal and large-scale mining are expanding in many African economies. While much has been written about contestation over land and mineral rights, the
Anderson D.M., Appiah K.A., Bank L., Barnes T.J., Beall J., Bebbington A., Brands H.W., Bridge G., Bridge G., Bryceson D.F., Bryceson D.F., Bryceson D.F., Bryceson D.F., Bryceson D.F., Bryceson D.F., Buijtenhuis R., Carstens P., Cooper F., Coquery-Vidrovitch C., Danny MacKinnon, De Boeck F., De Boeck F., De Boeck F., Deborah Bryceson, Dore E., Duffy R., Emel J., Ferguson J., Freudenberg W.R., Freudenburg W.R., Freund W., Freund W.M., Gluckman M., Godfrey B.J., Grätz T., Harries P., Hilson G., Hilson G., Hilson G., Holliday J.S., Jeeves A., Johnston R.J., Jønsson J.B., Kirk J.F., Laverty J.R., Lawrie M., Le Billon P., Le Billon P., Luning S.W.J., Mabin A., Mabin A., Mkandawire T., Moodie T.D., Morris R.J., Morris R.J., O'Connor A., Parks R., Peters K., Potts D., Rajak D., Rakodi C., Richards P., Ross M., Saad E.N., Smith M.D., Storey K., Swanson M., Tonts M., Vennetier P., Verhoeve A., Walker R.A., Walsh A., Walsh A., Welsby D.A., Werthman K., Wilks I., Wilson L.J., Wolpe H.   +77 more
core   +5 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source