Results 141 to 150 of about 7,040 (301)
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Mine Rescue Station Group Practicing
A man with bandages on his head and arm is tied to a stretcher. His head rests on folded blankets.
Martin's Photo Shop
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Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Mine rescue class. University of Idaho.
Postcard of students training for mine rescue operations in 1922 on the University of Idaho campus in Moscow, Idaho. | University of Idaho students have always been prepared.
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Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Innovative hydraulic support for mine rescue actions
W artykule omówiono rodzaje obudowy stosowanej w ratownictwie górniczym. Przedstawiono innowacyjne rozwiązania nowej obudowy dla ratownictwa górniczego, jak również możliwości zastosowania jej elementów w ratownictwie technicznym.Types of roof supports ...
Szyguła, M. +2 more
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ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
Kelowna Exploration Mine rescue team members wearing rescue gear. L to R: Ray Richards, Bill Richkum, Tony Triggs, Colin Brown, Ted Peck. Three men kneeling, L to R: Dibs Williams, Len James, George Mills. Note: same as photo #067 (notes say ca. 1953)
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