Results 41 to 50 of about 6,443,450 (298)
Study region: This study is based in the rapidly developing large-scale coal base located in Northwest China. Study focus: This study focuses on addressing a critical yet overlooked aspect of large-scale coal resource development in arid regions: the ...
Shihao Meng +7 more
doaj +1 more source
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
In this study, an orthogonal array experiment is conducted by using a transparent fracture network replica. Image processing and theoretical analysis are performed to investigate the model sealing efficiency (SE), factors influencing SE, and the effect ...
Guosheng Zheng +4 more
doaj +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
This paper describes the instability of river channel systems in alpine rockslide deposits using the Fernpass Rockslide and the river Loisach in the Tyrolian Außerfern District (Austria) as an example of paleoenvironmental developments. This is the first
Christian Wolkersdorfer
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Study on coal drawing parameters of deeply buried hard coal seams based on PFC
The coal seams in the Zhaogu mining area are characterized by great burial depth, hard coal quality, and difficulty in fracturing the top coal. To address the challenges of top-coal drawing in the working face, this study focuses on the external coal ...
Li Xinlei +3 more
doaj +1 more source
The intricate interplay between rock mechanics and fracture-induced fluid flow during resource extraction exerts profound effects on groundwater systems, posing a pivotal challenge for promoting green and safe development in underground engineering.
Shihao Meng +3 more
doaj +1 more source
The capacity of biochars derived from agricultural wastes to remove Cd(II) and Cu(II) from aqueous solution and contaminated mine water was evaluated using laboratory-based batch sorption experiments.
Tharanga Bandara +5 more
semanticscholar +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source

