Results 51 to 60 of about 98,174 (313)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Strength and microstructural properties of silt soil cured by lime-activated fly ash-GGBS under different curing temperatures

Scientific Reports
To reveal the mechanism of the influence of the curing temperature on the strength of lime activated fly ash-GGBS cured silt soil, the curing of dredged silt was carried out by using fly ash and GGBS as the curing agent and lime as the activator ...
Shunmei Gong, Songbao Feng, Shiquan Wang, Lemei Yu, Yuanyuan Chen, Qiang Xu   +5 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Hydrochemical characteristics and controlling factors of deep karst groundwater in Huaibei Plain, Huaihe River Basin, China

Frontiers in Earth Science
IntroductionDeep karst groundwater is an important object for groundwater resources development and utilisation in the context of increasing water scarcity, as well as a potential threat of water hazards to the deep mining of hidden coalfields in Huaihe ...
Wei Gong, Wei Gong, Chunjuan Zang, Chunjuan Zang, Jie Ma, Jie Ma, Yonggang Sun, Yonggang Sun, Haitao Zhang, Haitao Zhang, Pan Xu, Pan Xu, Mingming Jiang, Mingming Jiang   +13 more
doaj   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

The scientific and technical problems and solutions on shallow ground-source heat pump system

矿业科学学报, 2017
This paper discusses the concept and principle of shallow ground-source heat pump system(SGHPS) and studies the purpose and significance of its development.We analyze the key scientific and technical problems on SGHPS, including pump injection problem ...
Xu Shengheng, Zhou Tao, Sun Haizhou, Zeng Yifan, Liu Shouqiang, Wang Xiaolong, Wu Qiang   +6 more
doaj  

Transient Pressure Build-Up in Saturated Column System from Buffering-Induced CO₂ Generation: Implications for Soil Liquefaction in Lignite Overburden Dumps

Geotechnics
Spontaneous liquefaction in the Lusatian lignite dump sites has raised significant geotechnical and environmental concerns. While mechanical influences have been extensively studied, hydrochemical investigations suggest an inner initial that is highly ...
Donata N. W. Wardani, Nils Hoth, Sarah Amos, Kofi Moro, Johanes Maria Vianney, Carsten Drebenstedt   +5 more
doaj   +1 more source

Analysis on the Characteristics of Water Pollution Caused by Underground Mining and Research Progress of Treatment Technology

Advances in Civil Engineering, 2021
Coal is the primary source of energy in China’s energy structure system. With the large-scale mining of mineral resources, a large amount of mine water will be produced in the process of development, construction, and production, which will pollute and ...
Xinfeng Wang, Yuhao Gao, Xiaojun Jiang, Qiao Zhang, Wengang Liu   +4 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source