Results 91 to 100 of about 1,205,791 (198)
Point Mutations in Centromeric Histone Induce Post-zygotic Incompatibility and Uniparental Inheritance. [PDF]
The centromeric histone 3 variant (CENH3, aka CENP-A) is essential for the segregation of sister chromatids during mitosis and meiosis. To better define CENH3 functional constraints, we complemented a null allele in Arabidopsis with a variety of mutant ...
Britt, Anne B +6 more
core +3 more sources
Summary Algal blooms and their demise by viruses drive global‐scale ecological processes in the ocean. These blooms form the foundation of marine food webs, regulate microbial communities, and shape biogeochemical cycles. Although algal populations are constantly infected by viruses, resistant subpopulations frequently emerge after the infection.
Talia S. Shaler +5 more
wiley +1 more source
Meiotic behavior of small chromosomes in maize [PDF]
The typical behavior of chromosomes in meiosis is that homologous pairs synapse, recombine, and then separate at anaphase I. At anaphase II, sister chromatids separate.
Fangpu Han, James A. Birchler
core +2 more sources
Targeting Kupffer cells (KC) with a single intravenous infusion of the oncolytic virus VSV‐M51R rather than VSV‐WT induces effective tumor regression in various types of liver metastatic cancers in mice. VSV‐M51R promotes KC proliferation and enhances their antigen cross‐presentation capacity without compromising viability, leading to the induction of ...
Chen Chen +8 more
wiley +1 more source
ABSTRACT Maternally inherited transcripts are crucial for the developmental competence of salmon embryos. Due to the wide variety of broodstock conditioning approaches used in commercial aquaculture, there is a need to understand how dynamic commercial environments impact the egg transcriptome and subsequent quality.
Xin Zhan +4 more
wiley +1 more source
Ru Chen,1,2,* Bing Hu,1,* Ming Jiang,1,* Wen Deng,1 Ping Zheng,3 Bin Fu1,4 1Department of Urology, the First Affiliated Hospital of Nanchang University, Nanchang City, Jiangxi Province, People’s Republic of China; 2Department of Urology, The ...
Chen R +5 more
doaj
Taxonomic revision of the genus Lactarius (Russulales, Basidiomycota) in Korea [PDF]
The genus Lactarius Pers. (Russulales) is a cosmopolitan group of Basidiomycota that forms ectomycorrhizal relationships primarily with both deciduous and coniferous trees.
Eimes, John +5 more
core +1 more source
1. Ras inhibition (Salirasib) combined with c‐Myc targeting blocks MCM2‐driven DNA replication, inducing cell‐cycle arrest and apoptosis. 2. Dual inhibition remodels the immunosuppressive TME, polarising macrophages to M1 and enhancing PD‐L1 blockade efficacy. 3.
Xiaojie Liang +7 more
wiley +1 more source
Epigenetic Regulation of Hepatitis B Virus Covalently Closed Circular DNA: Implications for Epigenetic Therapy against Chronic Hepatitis B [PDF]
Hepatitis B virus (HBV) infection represents a significant public health burden worldwide. Although current therapeutics manage to control the disease progression, lifelong treatment and surveillance are required because drug resistance develops during ...
Guo, Haitao, Hong, Xupeng, Kim, Elena S.
core +1 more source
Heart Regeneration and Repair: Molecular Mechanism and Therapeutic Targets
Regarding the general picture of heart regeneration therapy, it encompasses exogenous cell therapy, endogenous medications, metabolism, interventions in gene pathways, as well as the therapeutic strategies in the burgeoning interdisciplinary field of medicine and engineering in recent years.
Mingchuan Liu +9 more
wiley +1 more source

