Bioinformatics analysis of the transcriptional expression of minichromosome maintenance proteins as potential indicators of survival in patients with cervical cancer. [PDF]
BMC Cancer, 2021 As major regulators of DNA replication in eukaryotes, minichromosome maintenance (MCM) proteins play an important role in the initiation and extension of DNA replication.
Wu B, Xi S.
europepmc +4 more sources
Immunohistochemical analysis of proliferating cell nuclear antigen and minichromosome maintenance complex component 7 in benign and malignant salivary gland tumors. [PDF]
Dent Res J (Isfahan), 2022 Background: Proliferation markers have been used to determine the behavior and prognosis of benign and malignant tumors; this study was aimed to compare the immunohistochemical (IHC) expression of proliferating cell nuclear antigen (PCNA) and novel ...
Shamloo N +3 more
europepmc +3 more sources
Over-Activation of Minichromosome Maintenance Protein 10 Promotes Genomic Instability in Early Stages of Breast Cancer. [PDF]
Int J Biol Sci, 2022 Genomic instability is considered as one of the key hallmark during cancer development and progression. Cellular mechanisms, such as DNA replication initiation, DNA damage and repair response, apoptosis etc are observed to block progression of genomic ...
Mughal MJ +5 more
europepmc +4 more sources
Destabilization of the MiniChromosome Maintenance (MCM) complex modulates the cellular response to DNA double strand breaks. [PDF]
Cell Cycle, 2018 DNA replication during S phase involves thousands of replication forks that must be coordinated to ensure that every DNA section is replicated only once.
Drissi R +6 more
europepmc +5 more sources
Correction to: Minichromosome maintenance 3 promotes hepatocellular carcinoma radioresistance by activating the NF-κB pathway [PDF]
Journal of Experimental & Clinical Cancer Research, 2019 In the original publication of this article [1], the authors reported the order of the authors was incorrect and needs to be revised. The original article has been updated to rectify this error.
Qing Yang +9 more
doaj +5 more sources
Minichromosome maintenance gene family: potential therapeutic targets and prognostic biomarkers for lung squamous cell carcinoma. [PDF]
Aging (Albany NY), 2022 The minichromosome maintenance (MCM) gene family comprises of ten members with key roles in eukaryotic DNA replication and are associated with the occurrence and progression of many tumors.
Yang X +5 more
europepmc +2 more sources
The High Expression of Minichromosome Maintenance Complex Component 5 Is an Adverse Prognostic Factor in Lung Adenocarcinoma. [PDF]
Biomed Res Int, 2022 Background Minichromosome maintenance (MCM) genes are crucial for genomic DNA replication and are important biomarkers in tumor biology. In this study, we aimed to identify the diagnostic, therapeutic, and prognostic value of the MCM2–10 genes in ...
Sun M +5 more
europepmc +2 more sources
Distinct Diagnostic and Prognostic Values of Minichromosome Maintenance Gene Expression in Patients with Hepatocellular Carcinoma. [PDF]
J Cancer, 2018 Background: The aim of the present study was to identify diagnostic and prognostic values of minichromosome maintenance (MCM) gene expression in patients with hepatocellular carcinoma (HCC).
Liao X +15 more
europepmc +4 more sources
Immunohistochemical expression and evaluation of cyclin D1 and minichromosome maintenance 2 in oral squamous cell carcinoma and verrucous carcinoma. [PDF]
J Oral Maxillofac Pathol, 2022 Background: The study of cell proliferation is important for assessing the tumor behavior, prognosis and patient survival of oral carcinomas. As literature search did not reveal sufficient studies of immunohistochemical expression of cyclin D1 and ...
Menaka TR +5 more
europepmc +2 more sources
Minichromosome maintenance 2 is an independent predictor of survival in patients with lung adenocarcinoma. [PDF]
Mol Clin Oncol, 2022 Minichromosome maintenance (MCM) protein deregulation is associated with tumor formation, progression and malignant transformation. MCM2 is frequently expressed during premalignant lung cell proliferation and is a sensitive marker for the early detection
Sakai H +12 more
europepmc +2 more sources