Results 71 to 80 of about 1,205,791 (198)
American Journal of Experimental and Clinical Research, 2021 Thyroid nodules are often discovered incidentally in the clinical practice. Even though definite preoperative diagnosis of follicular thyroid lesions prevents unnecessary thyroid surgeries, fine needle aspiration (FNA) cannot definitely differentiate ...
Mahmood Akhavan Tafti +6 more
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Neoplasia: An International Journal for Oncology Research, 2014 Genetic instability has emerged as an important hallmark of human neoplasia. Although most types of cancers exhibit genetic instability to some extent, in colorectal cancers genetic instability is a distinctive characteristic.
Mauricio Quimbaya +8 more
doaj +1 more source
PLoS Pathogens, 2022 Hepatitis B virus (HBV) covalently closed circular DNA (cccDNA), serving as the viral persistence form and transcription template of HBV infection, hijacks host histone and non-histone proteins to form a minichromosome and utilizes posttranslational ...
Elena S Kim +11 more
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Comparative transcriptome analysis between original and evolved recombinant lactose-consuming Saccharomyces cerevisiae strains [PDF]
, 2008 The engineering of Saccharomyces cerevisiae strains for lactose utilization has been attempted with the intent of developing high productivity processes for alcoholic fermentation of cheese whey. A recombinant S.
Adams +16 more
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The Origin Recognition Complex: From Origin Selection to Replication Licensing in Yeast and Humans
Biology, 2023 Understanding human DNA replication through the study of yeast has been an extremely fruitful journey. The minichromosome maintenance (MCM) 2–7 genes that encode the catalytic core of the eukaryotic replisome were initially identified through forward ...
Bik-Kwoon Tye, Yuanliang Zhai
doaj +1 more source
, 2005 Specific HPV DNA sequences are associated with more than 90% of invasive carcinomas of the uterine cervix. Viral E6 and E7 oncogenes are key mediators in cell transformation by disrupting TP53 and RB pathways. To investigate molecular mechanisms involved
Anne de La Rochefordière +15 more
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Low mutation percentage of KRAS and BRAF genes in Brazilian anal tumors [PDF]
, 2016 Anal cancer is a rare type of digestive tract disease, which has had a crescent incidence in a number of regions. Carcinomas are most frequently found, with squamous cell carcinoma (SCC) comprising similar to 95% of all anal tumors. The major risk factor
Bidinotto, Lucas Tadeu +10 more
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De novo formed satellite DNA-based mammalian artificial chromosomes and their possible applications. [PDF]
, 2015 Mammalian artificial chromosomes (MACs) are non-integrating, autonomously replicating natural chromosome-based vectors that may carry a vast amount of genetic material, which in turn enable potentially prolonged, safe, and regulated therapeutic transgene
Katona, Róbert László
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Journal of Cytology, 2017 Aims: We aimed to investigate the immunocytoexpression profiles of a novel assay ProEx C for topoisomerase II alpha (TOP2A) and minichromosome maintenance protein 2 (MCM2) in abnormal interpreted smears.
Zeynep Tosuner +5 more
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KSHV Genome Replication and Maintenance [PDF]
, 2016 Kaposi’s sarcoma associated herpesvirus (KSHV) or human herpesvirus 8 (HHV8) is a major etiological agent for multiple severe malignancies in immunocompromised patients.
Namrata Gupta +4 more
core +3 more sources