Results 211 to 220 of about 623,160 (229)
Some of the next articles are maybe not open access.
Minimal Change Disease: A Review
Southern Medical Journal, 2006Minimal change disease (MCD) is a histopathological lesion in the kidney that is most commonly associated with nephrotic syndrome. The majority of the cases are idiopathic. Pathogenesis is not well understood, although T-cell-related mechanisms are implicated.
Tapasi C, Saha, Harmeet, Singh
openaire +2 more sources
Advances in Kidney Disease and Health
Minimal change disease represents a common cause of nephrotic syndrome in both pediatric and adult patients. Although much remains to be discovered, there have been significant recent advancements in our understanding of the pathophysiology of minimal change disease, including the discovery of antinephrin antibodies as a marker for diagnosis of disease.
Alexis C. Gomez +2 more
openaire +3 more sources
Minimal change disease represents a common cause of nephrotic syndrome in both pediatric and adult patients. Although much remains to be discovered, there have been significant recent advancements in our understanding of the pathophysiology of minimal change disease, including the discovery of antinephrin antibodies as a marker for diagnosis of disease.
Alexis C. Gomez +2 more
openaire +3 more sources
Minimal change disease in pregnancy
The Journal of Maternal-Fetal & Neonatal Medicine, 2013New onset minimal change disease (MCD) is rare in pregnancy with the potential for serious complications including acute kidney injury (AKI).A case of MCD was diagnosed at 19 weeks gestation by renal biopsy. Within one month of starting steroids, the patient experienced normalization of renal function and resolution of nephrotic syndrome, although ...
Jamie O, Lo +3 more
openaire +2 more sources
2015
Abstract Minimal change disease is the most common cause of nephrotic syndrome in childhood but is not rare in adults. The factors altering permeability of the glomerular filtration barrier are not known, but podocyte structure is significantly altered in the condition and it seems certain that this cell is the target of whatever factors
Patrick Niaudet, Alain Meyrier
+4 more sources
Abstract Minimal change disease is the most common cause of nephrotic syndrome in childhood but is not rare in adults. The factors altering permeability of the glomerular filtration barrier are not known, but podocyte structure is significantly altered in the condition and it seems certain that this cell is the target of whatever factors
Patrick Niaudet, Alain Meyrier
+4 more sources
Clinical Queries: Nephrology, 2014
Abstract Minimal change disease is the commonest cause of nephrotic syndrome in children and third most common cause in adults. There are new insights in the pathogenesis of disease, and it is now considered a podocyte disorder. New biomarkers have been identified to explain the pathogenesis.
Howard Trachtman +2 more
openaire +2 more sources
Abstract Minimal change disease is the commonest cause of nephrotic syndrome in children and third most common cause in adults. There are new insights in the pathogenesis of disease, and it is now considered a podocyte disorder. New biomarkers have been identified to explain the pathogenesis.
Howard Trachtman +2 more
openaire +2 more sources
American Journal of Kidney Diseases, 1999
y Dis. 1999;33(3):E1 Fig 1. Glomeruli are normal by light microscopy in minimal change disease, as shown in this biopsy. The glomerular basement membrane is thin and delicate, and mesangial cellularity and matrix are within normal limits. There was no interstitial fibrosis and no segmental sclerosis in any of the glomeruli sampled.
openaire +1 more source
y Dis. 1999;33(3):E1 Fig 1. Glomeruli are normal by light microscopy in minimal change disease, as shown in this biopsy. The glomerular basement membrane is thin and delicate, and mesangial cellularity and matrix are within normal limits. There was no interstitial fibrosis and no segmental sclerosis in any of the glomeruli sampled.
openaire +1 more source
De novo minimal change disease
American Journal of Kidney Diseases, 1998Beyond the acute posttransplantation period, glomerular causes of proteinuria in the renal allograft include recurrent glomerulopathy, transplant-associated entities, and de novo disease. We present a case of de novo minimal change disease with reversible acute renal failure occurring 2.5 years posttransplantation in a 56-year-old man. The cause of end-
G S, Markowitz +3 more
openaire +2 more sources
Clinical Nephrology, 2016
To compare the clinicopathological characteristics, treatment response, and prognosis between patients with IgAN nephropathy with minimal change disease (MCD-IgAN) and patients with minimal change disease (MCD).77 patients with biopsy-proven MCD-IgAN from the Jinling Hospital IgAN Registry and 77 patients with MCD followed up for ≥ 3 years were ...
Xiao-Wei, Li +6 more
openaire +2 more sources
To compare the clinicopathological characteristics, treatment response, and prognosis between patients with IgAN nephropathy with minimal change disease (MCD-IgAN) and patients with minimal change disease (MCD).77 patients with biopsy-proven MCD-IgAN from the Jinling Hospital IgAN Registry and 77 patients with MCD followed up for ≥ 3 years were ...
Xiao-Wei, Li +6 more
openaire +2 more sources
Minimal Change Disease in Adults
2013Minimal change disease (MCD) is the etiology of the nephrotic syndrome in the majority of children and up to one-fourth of adults with this condition. The pathophysiology of MCD is poorly understood, but recent studies suggest the roles of regulatory T-cell dysfunction and specific podocyte proteins in its pathogenesis.
Jonathan Hogan, Jai Radhakrishnan
openaire +1 more source