Minimal doubly resolving set - Open Access .click

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Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source

Atomic masses of intermediate-mass neutron-deficient nuclei with relative uncertainty down to 35-ppb via multireflection time-of-flight mass spectrograph

, 2018
High-precision mass measurements of $^{63}$Cu, $^{64-66}$Zn, $^{65}$Ga, $^{65-67}$Ge, $^{67}$As, $^{78,81}$Br, $^{80}$Rb, and $^{79}$Sr were performed utilizing a multireflection time-of-flight mass spectrograph combined with the gas-filled recoil ion ...
Haba, H. +20 more
core +3 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source

Edge Version of Metric Dimension and Doubly Resolving Sets of the Necklace Graph

Mathematics, 2018
Consider an undirected and connected graph G = ( V G , E G ) , where V G and E G represent the set of vertices and the set of edges respectively. The concept of edge version of metric dimension and doubly resolving sets is based on the distances of edges
Jia-bao Liu, Zohaib Zahid, R. Nasir, W. Nazeer +3 more
semanticscholar +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source

Metric Dimension of Amalgamation of Graphs [PDF]

, 2013
A set of vertices $S$ resolves a graph $G$ if every vertex is uniquely determined by its vector of distances to the vertices in $S$. The metric dimension of $G$ is the minimum cardinality of a resolving set of $G$.
Saputro, Suhadi Wido +2 more
core

5D UED: Flat and Flavorless

, 2010
5D UED is not automatically minimally flavor violating. This is due to flavor asymmetric counter-terms required on the branes. Additionally, there are likely to be higher dimensional operators which directly contribute to flavor observables.
A Delgado +42 more
core +1 more source

Search for the doubly charmed baryon Ξcc+\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\Xi_{cc}^+$$\end{document}

Science China Physics Mechanics and Astronomy, 2019
A search for the doubly charmed baryon Ξcc+\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt}
R. Aaij +499 more
semanticscholar +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source

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