Results 131 to 140 of about 472,488 (296)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
The “PRO-N” clitic en / ne and the theory of cliticization
Bucharest Working Papers in Linguistics, 2012 The Romance pro-N clitic (Fr., Cat.) en / (It.) ne is problematic for most theories of cliticization,because some phenomena support a movement analysis, while others seem to speak against movement.Endorsing the view that the pro-N clitic is the result of
Ion Giurgea
doaj
Equivalents of Certain Minimal Element Principles
, 2023 In this article, by applying our 2023 Metatheorem in ordered fixed point theory, we obtain various MinimalElement Principles with their equivalent formulations to existence theorems on minimal elements, commonfixed points, common stationary points, and others. Some known theorems and new ones appear in suchequivalents.
openaire +2 more sources
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Explicit Free Resolutions of Tangent Cones in Affine 4-Space
Cumhuriyet Science JournalThis paper is devoted to the study of minimal free resolutions of tangent cones associated with complete intersection monomial curves in affine 4-space. By applying the gluing technique for numerical semigroups, we characterize specific families of these
Özgür İnce
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Punti distinti in P^2 con funzione di Hilbert generica
Le Matematiche, 1991 Let X be a set of distinct points in “generic position” in P2k , k algebraically closed field of characteristic zero. We describe the base locus for the system of curves of minimal degree passing through X, provided that the homgeneous ideal I(X) has a ...
Lucia Doretti
doaj
On the representation of minimal form factors in integrable quantum field theory
Nuclear Physics BIn this paper, we propose a new representation of the minimal form factors in integrable quantum field theories. These are solutions of the two-particle form factor equations, which have no poles on the physical sheet.
Olalla A. Castro-Alvaredo +2 more
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source