Results 51 to 60 of about 1,438,673 (245)
Muscle alterations are associated with minimal and overt hepatic encephalopathy in patients with liver cirrhosis [PDF]
, 2019 Muscle alterations (myosteatosis and sarcopenia) are frequent in cirrhosis and related to some complications included overt hepatic encephalopathy. The aim of our study was to investigate the relationship between muscle alterations and minimal hepatic ...
Ridola, Lorenzo +13 more
core +1 more source
Prevalence of Covert Hepatic Encephalopathy in A Tertiary Care Centre
Journal of Nepal Medical Association, 2020 Introduction: Among patients with Hepatic Encephalopathy, prevalence of Minimal HE varies between 30-50%. Identifying patients with MHE has been shown to improve with medications and delay development of Overt HE, however only limited clinicians screen ...
Rahul Pathak +4 more
doaj +1 more source
P- 91 CHANGES IN EARLY VISUAL PERCEPTION IN PATIENTS WITH MINIMAL HEPATIC ENCEPHALOPATHY
Annals of Hepatology, 2023 Introduction and Objectives: Minimal Hepatic Encephalopathy (MHE) is characterized by very subtle cognitive changes that are diagnosed with the Psychometric hepatic encephalopathy score (PHES) and critical flickering frequency (CFF).
José Luis Pérez Hernández +7 more
doaj +1 more source
Ammonia, infection and inflammation in hepatic encephalopathy. [PDF]
, 2007 For over a century, we have known that ammonia is important in the pathogenesis of hepatic encephalopathy. Studies in patients with acute liver failure have shown rapid progression to severe encephalopathy in those patients with evidence of a systemic ...
Shawcross, D.L. +1 more
core
Minimal hepatic encephalopathy and sleep disorders in patients with cirrhosis. Which comes first? [PDF]
, 2020 In this editorial authors discuss a paper published on Saudi Journal of Gastroenterology that investigate the relationship between minimal hepatic encephalopathy and sleep disorders among patients with ...
Riggio O. +7 more
core +1 more source
Current Management of Hepatic Encephalopathy: A Review Article [PDF]
, 2023 Hepatic encephalopathy, a neuropsychiatric syndrome stemming from liver failure, manifests in acute and chronic cases. The prevailing cause behind its development involves the neurotoxicity resulting from elevated ammonia levels in the brain, which can ...
Ghosh , Jhumur, Ghosh, Jaya
core +1 more source
Advanced Science, EarlyView.Lactate and H4K12la are elevated in Parkinson's disease. Mechanistically, p300‐mediated H4K12la enrichment at the HIF‐1α promoter upregulates HIF‐1α, which represses Ndufs1, impairing mitochondrial respiration and energy homeostasis in DA neurons.
Yingyao Liu +15 more
wiley +1 more source
Advanced Science, EarlyView.This review presents a pathology‐driven framework unifying nanomedicine across TBI, SCI, and PNI. Epidemiological evidence and comparative single‐cell transcriptomic reanalysis define shared pathological modules, injury‐specific effectors, and therapeutic bottlenecks. Six functional paradigms connect nanomaterial structure and biological fate to injury‐
Mouyuan Sun +12 more
wiley +1 more source
The Peripheral Benzodiazepine Receptor and Neurosteroids in Hepatic Encephalopathy
, 1997 Hepatic encephalopathy (HE) represents one of the most common events in terminal liver failure. Acute HE (fulminant hepatic failure, FHF) presents with the abrupt onset of delirium, seizures, and coma, and has a mortality rate of about 90%. The principal
Norenberg, Michael D +5 more
core +2 more sources
CYP3A5 genetic variability influences sildenafil and metabolite in pulmonary hypertension
British Journal of Clinical Pharmacology, EarlyView.Aim Interindividual variability in sildenafil response among pulmonary hypertension patients (PH) may be influenced by CYP3A5 polymorphisms. CYP3A5*3 allele reduces CYP3A5 activity and affects sildenafil metabolism. This study investigated the associations between CYP3A5 genotype and plasma concentrations of sildenafil and N‐desmethyl sildenafil, as ...
Pranisa Wongwien +7 more
wiley +1 more source