Results 81 to 90 of about 669,953 (290)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
All-Arthroscopic Intratendinous Dermal Patch Integration for Large-Sized Rotator Cuff Tear
Arthroscopy TechniquesPatch augmentation of rotator cuff repair can create a healed tendon-bone interface, rather than the formation of a fibrovascular scar tissue, seen even after maximizing biomechanical strength of repair with a double-row construct.
Sreejith Thampy J., M.S. Ortho +2 more
doaj +1 more source
Biocellulose for Incisional Hernia Repair—An Experimental Pilot Study
Nanomaterials, 2019 Ventral or incisional hernia are a common disease pattern in general surgery. Most commonly, a mesh repair is used for reconstruction, whereby the mesh itself might cause complications, like infections or adhesions.
Falk Rauchfuß +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Lifesaving increases life expectancy [PDF]
The notion of repeated minimal repair is analyzed and applied to modeling the lifesaving procedure of organisms. Under certain assumptions the equivalence between demographic lifesaving model and reliability shock model is proved.
Maxim S. Finkelstein
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Arthroscopic Repair of Extensor Carpi Radialis Brevis in Patients With Tennis Elbow
Arthroscopy TechniquesLateral epicondylitis, or tennis elbow, has been attributed to the degeneration of the extensor carpi radialis brevis tendon, with surgery reserved for recalcitrant cases.
Zhang Hailong, M.D., Ph.D. +1 more
doaj +1 more source
Endovascular management of a late saccular aortic aneurysm after end-to-end repair of coarctation
Monaldi Archives for Chest Disease, 2015 Post-coarctation surgical repair aneurysm formation is observed rarely with end-to-end anastomosis technique. The redo surgery is associated with high mortality and morbidity rate.
Christophoros Kotoulas +3 more
doaj +1 more source
Improved objective Bayesian estimator for a PLP model hierarchically represented subject to competing risks under minimal repair regime. [PDF]
PLoS One, 2021 Louzada F +18 more
europepmc +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source