Results 31 to 40 of about 768,787 (306)
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Variationally Improved Bézier Surfaces with Shifted Knots
Advances in Mathematical Physics, 2021 The Plateau-Bézier problem with shifted knots is to find the surface of minimal area amongst all the Bézier surfaces with shifted knots spanned by the admitted boundary.
Daud Ahmad +5 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Stability of vertical minimal surfaces in three-dimensional sub-Riemannian manifolds
Pracì Mìžnarodnogo Geometričnogo CentruWe obtain first and second variation formulae for minimal surfaces in three-dimensional sub-Riemannian manifolds which are vertical, i.e., perpendicular to the horizontal distribution of the sub-Riemannian structure.
Eugene Petrov, Ihor Havrylenko
doaj +1 more source
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
Kuwait Journal of Science, 2020 In this study, we define general rectifying ruled surfaces in the Euclidean 3-space E^3. We give some characterizations of rectifying ruled surfaces by considering the curvatures of base curve.
Mehmet Önder, Tanju Kahraman
doaj
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
A Note on Minimal Translation Graphs in Euclidean Space
Mathematics, 2019 In this note, we give a characterization of a class of minimal translation graphs generated by planar curves. Precisely, we prove that a hypersurface that can be written as the sum of n planar curves is either a hyperplane or a cylinder on the ...
Dan Yang, Jingjing Zhang, Yu Fu
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source